Host–microbial interactions in metabolic diseases: from diet to immunity

Ju-Hyung Lee; Joo-Hong Park

doi:10.1007/s12275-022-2087-y

Articles

Page Path: HOME > J. Microbiol > Volume 60(6); 2022 > Article

Review
Host–microbial interactions in metabolic diseases: from diet to immunity: Ju-Hyung Lee , Joo-Hong Park; Journal of Microbiology 2022;60(6):561-575.
DOI: https://doi.org/10.1007/s12275-022-2087-y
Published online: May 5, 2022

School of Biological Sciences and Institute of Microbiology, Seoul National University, Seoul 08826, Republic of KoreaSchool of Biological Sciences and Institute of Microbiology, Seoul National University, Seoul 08826, Republic of Korea

Corresponding author: Joo-Hong Park , Tel: +82-2-880-2138,

Received: 24 February 2022 • Revised: 23 March 2022 • Accepted: 1 April 2022

60 Views
0 Download
5 Web of Science
4 Crossref
3 Scopus

Full Article

Abstract

Growing evidence suggests that the gut microbiome is an important contributor to metabolic diseases. Alterations in microbial communities are associated with changes in lipid metabolism, glucose homeostasis, intestinal barrier functions, and chronic inflammation, all of which can lead to metabolic disorders. Therefore, the gut microbiome may represent a novel therapeutic target for obesity, type 2 diabetes, and nonalcoholic fatty liver disease. This review discusses how gut microbes and their products affect metabolic diseases and outlines potential treatment approaches via manipulation of the gut microbiome. Increasing our understanding of the interactions between the gut microbiome and host metabolism may help restore the healthy symbiotic relationship between them.

Keywords: VosA-VelB-activated developmental gene;development;sensor histidine kinase;sterigmatocystin;velvet regulators

Figure & Data

References

Citations

Citations to this article as recorded by

Fecal Microbiota Transplantation: Indications, Methods, and Challenges
Jee Young Lee, Yehwon Kim, Jiyoun Kim, Jiyeun Kate Kim
Journal of Microbiology.2024; 62(12): 1057. CrossRef
Galectin-4 increases the ability of M2 macrophages to enhance antiviral CD4+ T-cell responses
In-Gu Lee, Yong-Hyun Joo, Hoyeon Jeon, Raehyuk Jeong, Eui Ho Kim, Hyunwoo Chung, Seong-il Eyun, Jeongkyu Kim, Young-Jin Seo, So-Hee Hong
Journal of Leukocyte Biology.2023; 113(1): 71. CrossRef
Microencapsulation of Bacteriophages for the Delivery to and Modulation of the Human Gut Microbiota through Milk and Cereal Products
Christina Schubert, Sabina Fischer, Kathrin Dorsch, Lutz Teßmer, Jörg Hinrichs, Zeynep Atamer
Applied Sciences.2022; 12(13): 6299. CrossRef
Beta-Glucan Alters Gut Microbiota and Plasma Metabolites in Pre-Weaning Dairy Calves
Zhengzhong Luo, Li Ma, Tao Zhou, Yixin Huang, Liben Zhang, Zhenlong Du, Kang Yong, Xueping Yao, Liuhong Shen, Shumin Yu, Xiaodong Shi, Suizhong Cao
Metabolites.2022; 12(8): 687. CrossRef

Cite this Article

Cite this Article: export Copy Download Format; Close

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

RIS — For EndNote, ProCite, RefWorks, and most other reference management software
BibTeX — For JabRef, BibDesk, and other BibTeX-specific software

Include:

Citation for the content below
Citation and abstract for the content below

Host–microbial interactions in metabolic diseases: from diet to immunity

J. Microbiol. 2022;60(6):561-575. Published online May 5, 2022

DOI: https://doi.org/10.1007/s12275-022-2087-y

Related articles