REVIEW] Antibiotic-resistant clones in Gram-negative pathogens: presence of global clones in Korea

Kwan Soo Ko

doi:10.1007/s12275-019-8491-2

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REVIEW] Antibiotic-resistant clones in Gram-negative pathogens: presence of global clones in Korea: Kwan Soo Ko; Journal of Microbiology 2019;57(3):195-202.
DOI: https://doi.org/10.1007/s12275-019-8491-2
Published online: October 2, 2018

Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon 16419, Republic of KoreaDepartment of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon 16419, Republic of Korea

Received: 7 September 2018 • Revised: 1 October 2018 • Accepted: 2 October 2018

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Abstract

Antibiotic resistance is a global concern in public health. Antibiotic-resistant clones can spread nationally, internationally, and globally. This review considers representative antibiotic-resistant Gram-negative bacterial clones–CTX-M- 15-producing ST131 in Escherichia coli, extended-spectrum β-lactamase-producing ST11 and KPC-producing ST258 in Klebsiella pneumoniae, IMP-6-producing, carbapenem-resistant ST235 in Pseudomonas aeruginosa, and OXA-23- producing global clone 2 in Acinetobacter baumannii–that have disseminated worldwide, including in Korea. The findings highlight the urgency for systematic monitoring and international cooperation to suppress the emergence and propagation of antibiotic resistance.

Keywords: Escherichia coli;Klebsiella pneumoniae;Pseudomonas aeruginosa;Acinetobacter baumannii

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REVIEW] Antibiotic-resistant clones in Gram-negative pathogens: presence of global clones in Korea

J. Microbiol. 2019;57(3):195-202. Published online October 2, 2018

DOI: https://doi.org/10.1007/s12275-019-8491-2

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