REVIEW] Antibiotic-resistant clones in Gram-negative pathogens: presence of global clones in Korea

Kwan Soo Ko

doi:10.1007/s12275-019-8491-2

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REVIEW] Antibiotic-resistant clones in Gram-negative pathogens: presence of global clones in Korea: Kwan Soo Ko; Journal of Microbiology 2019;57(3):195-202.
DOI: https://doi.org/10.1007/s12275-019-8491-2
Published online: October 2, 2018

Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon 16419, Republic of Korea

Received: 7 September 2018 • Revised: 1 October 2018 • Accepted: 2 October 2018

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Abstract

Antibiotic resistance is a global concern in public health. Antibiotic-resistant clones can spread nationally, internationally, and globally. This review considers representative antibiotic-resistant Gram-negative bacterial clones–CTX-M- 15-producing ST131 in Escherichia coli, extended-spectrum β-lactamase-producing ST11 and KPC-producing ST258 in Klebsiella pneumoniae, IMP-6-producing, carbapenem-resistant ST235 in Pseudomonas aeruginosa, and OXA-23- producing global clone 2 in Acinetobacter baumannii–that have disseminated worldwide, including in Korea. The findings highlight the urgency for systematic monitoring and international cooperation to suppress the emergence and propagation of antibiotic resistance.

Keywords: Escherichia coli;Klebsiella pneumoniae;Pseudomonas aeruginosa;Acinetobacter baumannii

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REVIEW] Antibiotic-resistant clones in Gram-negative pathogens: presence of global clones in Korea

J. Microbiol. 2019;57(3):195-202. Published online October 2, 2018

DOI: https://doi.org/10.1007/s12275-019-8491-2

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