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- Host–microbial interactions in metabolic diseases: from diet to immunity
- Ju-Hyung Lee , Joo-Hong Park
- J. Microbiol. 2022;60(6):561-575. Published online May 5, 2022
- DOI: https://doi.org/10.1007/s12275-022-2087-y
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- 5 Web of Science
- 4 Crossref
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Abstract
- Growing evidence suggests that the gut microbiome is an important contributor to metabolic diseases. Alterations in microbial communities are associated with changes in lipid metabolism, glucose homeostasis, intestinal barrier functions, and chronic inflammation, all of which can lead to metabolic disorders. Therefore, the gut microbiome may represent a novel therapeutic target for obesity, type 2 diabetes, and nonalcoholic fatty liver disease. This review discusses how gut microbes and their products affect metabolic diseases and outlines potential treatment approaches via manipulation of the gut microbiome. Increasing our understanding of the interactions between the gut microbiome and host metabolism may help restore the healthy symbiotic relationship between them.
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Citations
Citations to this article as recorded by
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