Journal of Microbiology

Jin Yeul Ma

6 Articles

Interferon-mediated antiviral activities of Angelica tenuissima Nakai and its active components: Prasanna Weeratunga , Md Bashir Uddin , Myun Soo Kim , Byeong-Hoon Lee , Tae-Hwan Kim , Ji-Eun Yoon , Jin Yeul Ma , Hongik Kim , Jong-Soo Lee; J. Microbiol. 2018;56(9):690-690.; DOI: https://doi.org/10.1007/s12275-018-0579-6

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Abstract PDF: The above article by Weeratunga et al. has been retracted from Journal of Microbiology at the request of the corresponding author. The authors found that they were unable to reproduce Figure 1, Figure 3(A), Figure 4(A) and Figure 7(D) presented in this paper. All of the authors agreed to this retraction. The authors regret any inconvenience that this may cause and apologize sincerely to the readers, reviewers, and editors of Journal of Microbiology.

Dense Granule Protein-7 (GRA-7) of Toxoplasma gondii inhibits viral replication in vitro and in vivo: Prasanna Weeratunga , Thilina U. B. Herath , Tae-Hwan Kim , Hyun-Cheol Lee , Jae-Hoon Kim , Byeong-Hoon Lee , Eun-Seo Lee , Kiramage Chathuranga , W. A. Gayan Chathuranga , Chul-Su Yang , Jin Yeul Ma , Jong-Soo Lee; J. Microbiol. 2017;55(11):909-917. Published online October 27, 2017; DOI: https://doi.org/10.1007/s12275-017-7392-5

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Dense granule protein-7 (GRA-7) is an excretory protein of Toxoplasma gondii. It is a potential serodiagnostic marker and vaccine candidate for toxoplasmosis. Previous reports demonstrated that GRA-7 induces innate immune responses in macrophages by interacting with TRAF6 via the MyD88- dependent pathway. In the present study, we evaluated the antiviral activity and induction of an antiviral state by GRA-7 both in vitro and in vivo. It was observed that GRA-7 markedly reduced the replication of vesicular stomatitis virus (VSVGFP), influenza A virus (PR8-GFP), coxsackievirus (H3- GFP), herpes simplex virus (HSV-GFP), and adenovirus-GFP in epithelial (HEK293T/HeLa) and immune (RAW264.7) cells. These antiviral activities of GRA-7 were attributed to the induction of type I interferon (IFN) signaling, resulting in the secretion of IFNs and pro-inflammatory cytokines. Additionally, in BALB/c mice, intranasal administration of GRA-7 prevented lethal infection by influenza A virus (H1N1) and exhibited prophylactic effects against respiratory syncytial virus (RSV-GFP). Collectively, these results suggested that GRA-7 exhibits immunostimulatory and broad spectrum antiviral activities via type I IFN signaling. Thus, GRA-7 can be potentially used as a vaccine adjuvant or as a candidate drug with prophylactic potential against viruses.

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Kevin Roe
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Yuanxi Shen, Zhaozhe Wang, Jiajing Li, Rui Xu, Rongyi Ji, Jiaojiao Lin, Chuangang Zhu
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Coptidis Rhizoma extract inhibits replication of respiratory syncytial virus in vitro and in vivo by inducing antiviral state: Byeong-Hoon Lee , Kiramage Chathuranga , Md Bashir Uddin , Prasanna Weeratunga , Myun Soo Kim , Won-Kyung Cho , Hong Ik Kim , Jin Yeul Ma , Jong-Soo Lee; J. Microbiol. 2017;55(6):488-498. Published online May 28, 2017; DOI: https://doi.org/10.1007/s12275-017-7088-x

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Abstract PDF

Coptidis Rhizoma is derived from the dried rhizome of Ranun-culaceous plants and is a commonly used traditional Chinese medicine. Although Coptidis Rhizoma is commonly used for its many therapeutic effects, antiviral activity against respi-ratory syncytial virus (RSV) has not been reported in detail. In this study, we evaluated the antiviral activities of Coptidis Rhizoma extract (CRE) against RSV in human respiratory tract cell line (HEp2) and BALB/c mice. An effective dose of CRE significantly reduces the replication of RSV in HEp2 cells and reduces the RSV-induced cell death. This antiviral activity against RSV was through the induction of type I inter-feron-related signaling and the antiviral state in HEp2 cells. More importantly, oral administration of CRE exhibited prophylactic effects in BALB/c mice against RSV. In HPLC analysis, we found the presence of several compounds in the aqueous fraction and among them; we confirmed that pal-matine was related to the antiviral properties and immune- modulation effect. Taken together, an extract of Coptidis Rhi-zoma and its components play roles as immunomodulators and could be a potential source as promising natural antivirals that can confer protection to RSV. These outcomes should encourage further allied studies in other natural products.

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Molecules.2023; 28(14): 5398. CrossRef
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Anna A. Shtro, Elizaveta D. Gladkova, Anastasia V. Galochkina, Yulia V. Nikolaeva, Angelika V. Garshinina, Darya N. Razgulyaeva, Evgeniy V. Sorokin, Tatyana R. Tsareva, Olga A. Luzina, Nariman F. Salakhutdinov
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Qingshan Zhang, Gaowa Wang, Xi Chen, Zhiqiang Han, Xiangmei Chen, Risu Na, Haburi Jin, Ping Li, Renbatu Bu
European Journal of Drug Metabolism and Pharmacokinetics.2018; 43(4): 441. CrossRef

Interferon-mediated antiviral activities of Angelica tenuissima Nakai and its active components: Prasanna Weeratunga , Md Bashir Uddin , Myun Soo Kim , Byeong-Hoon Lee , Tae-Hwan Kim , Ji-Eun Yoon , Jin Yeul Ma , Hongik Kim , Jong-Soo Lee; J. Microbiol. 2016;54(1):57-70. Published online January 5, 2016; DOI: https://doi.org/10.1007/s12275-016-5555-4

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Abstract PDF

Angelica tenuissima Nakai is a widely used commodity in traditional medicine. Nevertheless, no study has been conducted on the antiviral and immune-modulatory properties of an aqueous extract of Angelica tenuissima Nakai. In the present study, we evaluated the antiviral activities and the mechanism of action of an aqueous extract of Angelica tenuissima Nakai both in vitro and in vivo. In vitro, an effective dose of Angelica tenuissima Nakai markedly inhibited the replication of Influenza A virus (PR8), Vesicular stomatitis virus (VSV), Herpes simplex virus (HSV), Coxsackie virus, and Enterovirus (EV-71) on epithelial (HEK293T/HeLa) and immune (RAW264.7) cells. Such inhibition can be described by the induction of the antiviral state in cells by antiviral, IFNrelated gene induction and secretion of IFNs and pro-inflammatory cytokines. In vivo, Angelica tenuissima Nakai treated BALB/c mice displayed higher survivability and lower lung viral titers when challenged with lethal doses of highly pathogenic influenza A subtypes (H1N1, H5N2, H7N3, and H9N2). We also found that Angelica tenuissima Nakai can induce the secretion of IL-6, IFN-λ, and local IgA in bronchoalveolar lavage fluid (BALF) of Angelica tenuissima Nakai treated mice, which correlating with the observed prophylactic effects. In HPLC analysis, we found the presence of several compounds in the aqueous fraction and among them; we evaluated antiviral properties of ferulic acid. Therefore, an extract of Angelica tenuissima Nakai and its components, including ferulic acid, play roles as immunomodulators and may be potential candidates for novel anti-viral/anti-influenza agents.

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Korean Journal of Dental Materials.2022; 49(4): 187. CrossRef
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Chang-Woo Ha, Eun-Hwa Sohn, Sung-Hyeok Kim, Sohee Jang, Myung-Rye Park, Youn-Kyu Kim, In-Young Bae
International Journal of Molecular Sciences.2022; 23(20): 12072. CrossRef
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Huan Li, Joonki Kim, Huynh Nguyen Khanh Tran, Chang Hwan Lee, Jonghyun Hur, Min Cheol Kim, Hyun Ok Yang
NeuroMolecular Medicine.2021; 23(3): 428. CrossRef
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Hyun Gyu Choi, In-Gyu Je, Geum Jin Kim, Joo-Won Nam, Sang Hee Shim, Sang-Hyun Kim, Hyukjae Choi
Natural Product Communications.2017;[Epub] CrossRef
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Journal of Microbiology.2016; 54(12): 853. CrossRef

Bacillus manliponensis sp. nov., a New Member of the Bacillus cereus Group Isolated from Foreshore Tidal Flat Sediment: Min Young Jung , Joong-Su Kim , Woon Kee Paek , Jeongheui Lim , Hansoo Lee , Pyoung Il Kim , Jin Yeul Ma , Wonyong Kim , Young-Hyo Chang; J. Microbiol. 2011;49(6):1027-1032. Published online December 28, 2011; DOI: https://doi.org/10.1007/s12275-011-1049-6

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Abstract PDF

A Gram-positive, endospore-forming, new Bacillus species, strain BL4-6T, was isolated from tidal flat sediment of the Yellow Sea. Strain BL4-6T is a straight rod, with motility by peritrichate flagella. The cell wall contains meso-diaminopimelic acid, and the major respiratory quinone is menaquinone-7. The major fatty acids are iso-C15:0 and summed feature 3 (containing C16:1 ω7c/ iso-C15:0 2OH, and/or iso-C15:0 2OH/C16:1 ω7c). Cells are catalase-positive and oxidase-negative. The G+C content of the genomic DNA is 38.0 mol%. Based on a comparative 16S rRNA gene sequence analysis, the isolate belongs to the genus Bacillus, forms a clade with the Bacillus cereus group, and is closely related to Bacillus mycoides (98.5%), Bacillus cereus (98.5%), Bacillus anthracis (98.4%), Bacillus thuringiensis (98.4%), Bacillus weihenstephanensis (98.1%), and Bacillus pseudomycoides (97.5%). The isolate showed less than 85% similarity of the gyrA gene sequence and below 95% similarity of the rpoB gene sequence to the members of this group. DNA-DNA relatedness between strain BL4-6T and B. cereus group was found to be in a range of 22.8-42.3%, and thus BL4-6T represents a unique species. On the basis of these studies, strain BL4-6T (=KCTC 13319T =JCM 15802T) is proposed to represent the type strain of a novel species, Bacillus manliponensis sp. nov.

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Genome Sequence Analysis of H5N1 Influenza A Virus Isolated from a Vietnamese in 2007: Dieu Linh Tran , Kangmo Kim , Jae Yoo Choi , Hyun Dong Paik , Si-Woo Choi , Jin Yeul Ma , Sung-Soon Kim , Sung Joon Ahn , Young Bong Kim; J. Microbiol. 2011;49(2):274-279. Published online May 3, 2011; DOI: https://doi.org/10.1007/s12275-011-0311-2

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Abstract PDF

Highly pathogenic H5N1 avian influenza A virus (AIV) crossed the species barrier and caused a number of deaths in humans in Vietnam and 14 other countries. Since the last report of human H5N1 infection in November 2005, the first documented H5N1 human infection was reported in June 2007 in Vietnam and was followed by 7 more cases, including 5 fatalities. In this study, we isolated and analyzed the full length of the H5N1 genome from a sample from the first patient in 2007. Phylogenetic analysis of eight genomic segments of the H5N1 virus strain (A/Vietnam/HN/2007, VNH07) revealed that this strain appears to be of genotype V and contains the HA gene, which is classified into clade 2.3.4. The deduced amino acid sequence of the HA protein has a typical affinity sequence for α2,3 linkage (SAα2,3-Gal) receptors and typical multibasic cleavage sequences. Compared with other H5N1 isolates, VNH07 showed that the possible reassortments for the NA and NP segments occurred between A/goose/Guangxi/3017/2005-like isolates (2.3.2) and A/human/Zhejiang/16/2006-like isolates (2.3.4).

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Rethinking Approaches to Improve the Utilization of Nucleic Acid Amplification Tests for Detection and Characterization of Influenza A in Diagnostic and Reference Laboratories
Kanti Pabbaraju, Sallene Wong, Steven J Drews
Future Microbiology.2011; 6(12): 1443. CrossRef

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