- Involvement of Curli Fimbriae in the Biofilm Formation of Enterobacter cloacae
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Sung-Min Kim , Hee-Woo Lee , Yeh-Wan Choi , Shuk-Ho Kim , Je-Chul Lee , Yoo-Chul Lee , Sung-Yong Seol , Dong-Taek Cho , Jungmin Kim
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J. Microbiol. 2012;50(1):175-178. Published online February 27, 2012
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DOI: https://doi.org/10.1007/s12275-012-2044-2
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Abstract
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In this study, we examined the biofilm forming ability, the
mRNA expression of curli genes and the morphologies of
curli fimbriae and biofilms in clinical isolates of Enterobacter
cloacae. The csgBA operon was found in 11 (78.6%) of the
14 isolates. The ability of E. cloacae isolates to form biofilms
was significantly correlated with the mRNA expression level
of the csgA and csgD genes. The curli protein fimbriae appeared
as tangled fibers and the curli-proficient strain formed
mature biofilms. Our data suggest that the expression of the
curli fimbriae play an important role in biofilm formation
in E. cloacae.
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