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HOME > J. Microbiol > Volume 50(1); 2012 > Article
Research Support, Non-U.S. Gov't
NOTE] Involvement of Curli Fimbriae in the Biofilm Formation of Enterobacter cloacae
Sung-Min Kim 1,2, Hee-Woo Lee 1,3, Yeh-Wan Choi 1, Shuk-Ho Kim 1, Je-Chul Lee 1, Yoo-Chul Lee 1, Sung-Yong Seol 1, Dong-Taek Cho 1, Jungmin Kim 1
Journal of Microbiology 2012;50(1):175-178.
DOI: https://doi.org/10.1007/s12275-012-2044-2
Published online: February 27, 2012
1Department of Microbiology, School of Medicine, Kyungpook National University, Daegu 700-422, Republic of Korea, 2Present address: †Division of Magnetic Resonance Research, Korea Basic Science Institute, Chungbook 363-883, Republic of Korea, 3Present address: ‡Department of Veterinary Internal Medicine, College of Veterinary
Corresponding author:  Jungmin Kim , Tel: +82-53-420-4845, 
Received: 27 January 2012   • Accepted: 9 February 2012
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Abstract

In this study, we examined the biofilm forming ability, the mRNA expression of curli genes and the morphologies of curli fimbriae and biofilms in clinical isolates of Enterobacter cloacae. The csgBA operon was found in 11 (78.6%) of the 14 isolates. The ability of E. cloacae isolates to form biofilms was significantly correlated with the mRNA expression level of the csgA and csgD genes. The curli protein fimbriae appeared as tangled fibers and the curli-proficient strain formed mature biofilms. Our data suggest that the expression of the curli fimbriae play an important role in biofilm formation in E. cloacae.

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    NOTE] Involvement of Curli Fimbriae in the Biofilm Formation of Enterobacter cloacae
    J. Microbiol. 2012;50(1):175-178.   Published online February 27, 2012
    DOI: https://doi.org/10.1007/s12275-012-2044-2
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