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- [Minireview]Biodegradation of plastics: mining of plastic-degrading microorganisms and enzymes using metagenomics approaches
- Dae-Wi Kim , Jae-Hyung Ahn , Chang-Jun Cha
- J. Microbiol. 2022;60(10):969-976. Published online September 27, 2022
- DOI: https://doi.org/10.1007/s12275-022-2313-7
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- 28 Web of Science
- 28 Crossref
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Abstract
- Plastic pollution exacerbated by the excessive use of synthetic plastics and its recalcitrance has been recognized among the most pressing global threats. Microbial degradation of plastics has gained attention as a possible eco-friendly countermeasure, as several studies have shown microbial metabolic capabilities as potential degraders of various synthetic plastics. However, still defined biochemical mechanisms of biodegradation for the most plastics remain elusive, because the widely used culture-dependent approach can access only a very limited amount of the metabolic potential in each microbiome. A culture-independent approach, including metagenomics, is becoming increasingly important in the mining of novel plastic-degrading enzymes, considering its more expanded coverage on the microbial metabolism in microbiomes. Here, we described the advantages and drawbacks associated with four different metagenomics approaches (microbial community analysis, functional metagenomics, targeted gene sequencing, and whole metagenome sequencing) for the mining of plastic-degrading microorganisms and enzymes from the plastisphere. Among these approaches, whole metagenome sequencing has been recognized among the most powerful tools that allow researchers access to the entire metabolic potential of a microbiome. Accordingly, we suggest strategies that will help to identify plastisphere-enriched sequences as de novo plastic-degrading enzymes using the whole metagenome sequencing approach. We anticipate that new strategies for metagenomics approaches will continue to be developed and facilitate to identify novel plastic-degrading microorganisms and enzymes from microbiomes.
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Citations
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- Advanced biotechnological tools towards achieving United Nations Sustainable Development Goals (UNSDGs) for mitigation of microplastics from environments: a review
Mukesh Kumar, Veena Chaudhary, Ravi Kumar, Manoj Kumar Yadav, Chetan Chauhan, Satya Prakash, Devanshu Shukla, Rishubh Motla, Krishna Kaushik, Virendra Pal, Mahesh Kumar, Rajat Singh, Arul Lal Srivastav
Discover Sustainability.2025;[Epub] CrossRef - Vaal’s Microplastic Burden: Uncovering the Fate of Microplastics in Emfuleni Municipality’s Wastewater Treatment Systems, Gauteng, South Africa
Tebogo Maleka, Richard Greenfield, Sudhakar Muniyasamy, Lee-Ann Modley
Sustainability.2025; 17(5): 2211. CrossRef - Unlocking the potential of Shewanella in metabolic engineering: Current status, challenges, and opportunities
Yi-Nan Liu, Zhourui Liu, Jian Liu, Yidan Hu, Bin Cao
Metabolic Engineering.2025; 89: 1. CrossRef - Exploring the Role of Plant Growth-Promoting Bacteria in Biodegradation of Plastic: A Review
Haris Maqbool, Fazal Ur Rehman, Izhar Khan, Nadeem Ullah, Muhammad Anwar Sajad, Nazir Mohammad, Maria Kalsoom, Shafiq Ur Rehman, Muhammad Farooq Hussain Munis, Malka Saba, Hassan Javed Chaudhary
Water, Air, & Soil Pollution.2025;[Epub] CrossRef - XenoBug: machine learning-based tool to predict pollutant-degrading enzymes from environmental metagenomes
Aditya S Malwe, Usha Longwani, Vineet K Sharma
NAR Genomics and Bioinformatics.2025;[Epub] CrossRef - Microbial diversity analysis of municipal solid waste landfills soils of Delhi (NCR) and plastic dump sites of Uttar Pradesh region of India and their function prediction for plastic degrading enzymes
Viral Kumar Tiwari, Akanksha Vishwakarma, Digvijay Verma, Monica Sharma
World Journal of Microbiology and Biotechnology.2025;[Epub] CrossRef - The Individual and Combined Effects of Microplastics and Antibiotics on Soil Microbial Metabolic Limitation and Carbon Use Efficiency
Qiuyue Zhang, Yi Tang, Yanjiao Wang, Pengfei Cheng, Lianghui Li, Babar Iqbal, Tingting Zhao, Ruoyu Guo, Xiaojun Zheng, Guanlin Li, Daolin Du
Land Degradation & Development.2025; 36(9): 2955. CrossRef - From biofilms to biocatalysts: Innovations in plastic biodegradation for environmental sustainability
Slavica Porobic Katnic, Ram K. Gupta
Journal of Environmental Management.2025; 374: 124192. CrossRef - Molecular docking and metagenomics assisted mitigation of microplastic pollution
Dinesh Parida, Konica Katare, Atmaadeep Ganguly, Disha Chakraborty, Oisi Konar, Regina Nogueira, Kiran Bala
Chemosphere.2024; 351: 141271. CrossRef - Recent advances in screening and identification of PET-degrading enzymes
Shengwei Sun
Environmental Reviews.2024; 32(3): 294. CrossRef - Metagenomic analysis of soil from landfill site reveals a diverse microbial community involved in plastic degradation
Akhilesh Kumar, Sudarshan Singh Lakhawat, Kashmir Singh, Vikram Kumar, Kumar Sambhav Verma, Umesh Kumar Dwivedi, S.L. Kothari, Naveen Malik, Pushpender Kumar Sharma
Journal of Hazardous Materials.2024; 480: 135804. CrossRef - PEZy-miner: An artificial intelligence driven approach for the discovery of plastic-degrading enzyme candidates
Renjing Jiang, Zhenrui Yue, Lanyu Shang, Dong Wang, Na Wei
Metabolic Engineering Communications.2024; 19: e00248. CrossRef - Mining strategies for isolating plastic-degrading microorganisms
Ziyao Zhang, Qi Zhang, Huihui Yang, Li Cui, Haifeng Qian
Environmental Pollution.2024; 346: 123572. CrossRef - Microenvironment of Landfill-Mined Soil-Like Fractions (LMSF): Evaluating the Polymer Composting Potential Using Metagenomics and Geoenvironmental Characterization
Arnab Banerjee, Charakho N. Chah, Manoj Kumar Dhal, Kshitij Madhu, Kiran Vilas Dhobale, Bharat Rattan, Vimal Katiyar, Sreedeep Sekharan
International Journal of Environmental Research.2024;[Epub] CrossRef - Progress in polystyrene biodegradation by insect gut microbiota
Luhui Xu, Zelin Li, Liuwei Wang, Zihang Xu, Shulin Zhang, Qinghua Zhang
World Journal of Microbiology and Biotechnology.2024;[Epub] CrossRef - Recent trends in microbial and enzymatic plastic degradation: a solution for plastic pollution predicaments
Swagata Lakshmi Dhali, Dinesh Parida, Bikash Kumar, Kiran Bala
Biotechnology for Sustainable Materials.2024;[Epub] CrossRef - Deconstructing PET: Advances in enzyme engineering for sustainable plastic degradation
Jiaxin Yao, Yao Liu, Zhenghua Gu, Liang Zhang, Zhongpeng Guo
Chemical Engineering Journal.2024; 497: 154183. CrossRef - Mechanistic Insights into Cellular and Molecular Basis of Protein‐Nanoplastic Interactions
Goutami Naidu, Nupur Nagar, Krishna Mohan Poluri
Small.2024;[Epub] CrossRef - Searching for new plastic-degrading enzymes from the plastisphere of alpine soils using a metagenomic mining approach
Beat Frey, Margherita Aiesi, Basil M. Rast, Joel Rüthi, Jérôme Julmi, Beat Stierli, Weihong Qi, Ivano Brunner, Sinosh Skarlyachan
PLOS ONE.2024; 19(4): e0300503. CrossRef - Discovery and characterization of two novel polyethylene terephthalate hydrolases: One from a bacterium identified in human feces and one from the Streptomyces genus
Zhengyang Han, Mario Roque Huanca Nina, Xiaoyan Zhang, Hanyao Huang, Daidi Fan, Yunpeng Bai
Journal of Hazardous Materials.2024; 472: 134532. CrossRef - Synthesis of Renewable and Cost-Effective Bioplastic from Apple Waste: Physicochemical and Biodegradability Studies
Nicholas Yung Li Loh, Hui Ying Pang, Wan Ting Tee, Billie Yan Zhang Hiew, Svenja Hanson, Siewhui Chong, Suchithra Thangalazhy-Gopakumar, Suyin Gan, Lai Yee Lee
Waste and Biomass Valorization.2023; 14(10): 3235. CrossRef - Validated High-Throughput Screening System for Directed Evolution of Nylon-Depolymerizing Enzymes
Hendrik Puetz, Christoph Janknecht, Francisca Contreras, Mariia Vorobii, Tetiana Kurkina, Ulrich Schwaneberg
ACS Sustainable Chemistry & Engineering.2023; 11(43): 15513. CrossRef - Perspectives on biorefineries in microbial production of fuels and chemicals
Stephen R. Decker, Roman Brunecky, John M. Yarbrough, Venkataramanan Subramanian
Frontiers in Industrial Microbiology.2023;[Epub] CrossRef - Microbial Enzyme Biotechnology to Reach Plastic Waste Circularity: Current Status, Problems and Perspectives
Marco Orlando, Gianluca Molla, Pietro Castellani, Valentina Pirillo, Vincenzo Torretta, Navarro Ferronato
International Journal of Molecular Sciences.2023; 24(4): 3877. CrossRef - Trends in in-silico guided engineering of efficient polyethylene terephthalate (PET) hydrolyzing enzymes to enable bio-recycling and upcycling of PET
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Computational and Structural Biotechnology Journal.2023; 21: 3513. CrossRef - From waste to resource: Metagenomics uncovers the molecular ecological resources for plastic degradation in estuaries of South China
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Water Research.2023; 242: 120270. CrossRef - Biodegradation of Different Types of Bioplastics through Composting—A Recent Trend in Green Recycling
Wazir Aitizaz Ahsan, Adnan Hussain, Chitsan Lin, Minh Ky Nguyen
Catalysts.2023; 13(2): 294. CrossRef - Biodegradation of Poly(ethylene terephthalate) by Bacillus safensis YX8
Caiting Zeng, Fanghui Ding, Jie Zhou, Weiliang Dong, Zhongli Cui, Xin Yan
International Journal of Molecular Sciences.2023; 24(22): 16434. CrossRef
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