Journal of Microbiology

Journal Articles

Characterization of a novel dsRNA mycovirus of Trichoderma atroviride NFCF377 reveals a member of “Fusagraviridae” with changes in antifungal activity of the host fungus: Jeesun Chun , Byeonghak Na , Dae-Hyuk Kim; J. Microbiol. 2020;58(12):1046-1053. Published online October 23, 2020; DOI: https://doi.org/10.1007/s12275-020-0380-1

55 View
0 Download
9 Web of Science
8 Crossref

Trichoderma atroviride is a common fungus found in various ecosystems that shows mycoparasitic ability on other fungi. A novel dsRNA virus was isolated from T. atroviride NFCF377 strain and its molecular features were analyzed. The viral genome consists of a single segmented double-stranded RNA and is 9,584 bp in length, with two discontinuous open reading frames (ORF1 and ORF2). A mycoviral structural protein and an RNA-dependent RNA polymerase (RdRp) are encoded by ORF1 and ORF2, respectively, between which is found a canonical shifty heptameric signal motif (AAAAAAC) followed by an RNA pseudoknot. Analysis of sequence similarity and phylogeny showed that it is closely related to members of the proposed family “Fusagraviridae”, with a highest similarity to the Trichoderma atroviride mycovirus 1 (TaMV1). Although the sequence similarity of deduced amino acid to TaMV1 was evident, sequence deviations were distinctive at untranslated regions (UTRs) due to the extended size. Thus, we inferred this dsRNA to be a different strain of Trichoderma atroviride mycovirus 1 (TaMV1-NFCF377). Electron microscopy image exhibited an icosahedral viral particle of 40 nm diameter. Virus-cured isogenic isolates were generated and no differences in growth rate, colony morphology, or conidia production were observed between virus-infected and virus-cured strains. However, culture filtrates of TaMV1- NFCF377-infected strain showed enhanced antifungal activity against the plant pathogen Rhizoctonia solani but not to edible mushroom Pleurotus ostreatus. These results suggested that TaMV1-NFCF377 affected the metabolism of the fungal host to potentiate antifungal compounds against a plant pathogen, but this enhanced antifungal activity appeared to be species-specific.

Citations

Citations to this article as recorded by

Co-infection with two novel mycoviruses affects the biocontrol activity of Trichoderma polysporum
Jeesun Chun, Hae-Ryeong Yoon, Sei-Jin Lee, Dae-Hyuk Kim
Biological Control.2024; 188: 105440. CrossRef
An Outstandingly Rare Occurrence of Mycoviruses in Soil Strains of the Plant-Beneficial Fungi from the Genus Trichoderma and a Novel Polymycoviridae Isolate
Chenchen Liu, Xiliang Jiang, Zhaoyan Tan, Rongqun Wang, Qiaoxia Shang, Hongrui Li, Shujin Xu, Miguel A. Aranda, Beilei Wu, Lea Atanasova
Microbiology Spectrum.2023;[Epub] CrossRef
Sixteen Novel Mycoviruses Containing Positive Single-Stranded RNA, Double-Stranded RNA, and Negative Single-Stranded RNA Genomes Co-Infect a Single Strain of Rhizoctonia zeae
Siwei Li, Zhihao Ma, Xinyi Zhang, Yibo Cai, Chenggui Han, Xuehong Wu
Journal of Fungi.2023; 10(1): 30. CrossRef
Trichoderma – genomes and genomics as treasure troves for research towards biology, biotechnology and agriculture
Miriam Schalamun, Monika Schmoll
Frontiers in Fungal Biology.2022;[Epub] CrossRef
A Transfectable Fusagravirus from a Japanese Strain of Cryphonectria carpinicola with Spherical Particles
Subha Das, Sakae Hisano, Ana Eusebio-Cope, Hideki Kondo, Nobuhiro Suzuki
Viruses.2022; 14(8): 1722. CrossRef
Molecular characteristics of a novel hypovirus from Trichoderma harzianum
Jeesun Chun, Kum-Kang So, Yo-Han Ko, Dae-Hyuk Kim
Archives of Virology.2022; 167(1): 233. CrossRef
Sustainable Management of Medicago sativa for Future Climates: Insect Pests, Endophytes and Multitrophic Interactions in a Complex Environment
Mark R. McNeill, Xiongbing Tu, Eric Altermann, Wu Beilei, Shengjing Shi
Frontiers in Agronomy.2022;[Epub] CrossRef
A New Double-Stranded RNA Mycovirus in Cryphonectria naterciae Is Able to Cross the Species Barrier and Is Deleterious to a New Host
Carolina Cornejo, Sakae Hisano, Helena Bragança, Nobuhiro Suzuki, Daniel Rigling
Journal of Fungi.2021; 7(10): 861. CrossRef

The antimicrobial potential of a new derivative of cathelicidin from Bungarus fasciatus against methicillin-resistant Staphylococcus aureus: Mercedeh Tajbakhsh , Abdollah Karimi , Abolghasem Tohidpour , Naser Abbasi , Fatemeh Fallah , Maziar Mohammad Akhavan; J. Microbiol. 2018;56(2):128-137. Published online February 2, 2018; DOI: https://doi.org/10.1007/s12275-018-7444-5

57 View
0 Download
19 Crossref

Abstract

Cathelicidins are a family of antimicrobial peptides which exhibit broad antimicrobial activities against antibiotic-resistant bacteria. Considering the progressive antibiotic resistance, cathelicidin is a candidate for use as an alternative approach to treat and overcome the challenge of antimicrobial resistance. Cathelicidin-BF (Cath-BF) is a short antimicrobial peptide, which was originally extracted from the venom of Bungarus fasciatus. Recent studies have reported that Cath-BF and some related derivatives exert strong antimicrobial and weak hemolytic properties. This study investigates the bactericidal and cytotoxic effects of Cath-BF and its analogs (Cath-A and Cath-B). Cath-A and Cath-B were designed to increase their net positive charge, to have more activity against methicillin resistant S. aureus (MRSA). The results of this study show that Cath-A, with a +17-net charge, has the most noteworthy antimicrobial activity against MRSA strains, with minimum inhibitory concentration (MIC) ranging between 32–128 μg/ml. The bacterial kinetic analysis by 1 × MIC concentration of each peptide shows that Cath-A neutralizes the clinical MRSA isolate for 60 min. The present data support the notion that increasing the positive net charge of antimicrobial peptides can increase their potential antimicrobial activity. Cath-A also displayed the weakest cytotoxicity effect against human umbilical vein endothelial and H9c2 rat cardiomyoblast cell lines. Analysis of the hemolytic activity reveals that all three peptides exhibit minor hemolytic activity against human erythrocytes at concentrations up to 250 μg/ml. Altogether, these results suggest that Cath-A and Cath-B are competent candidates as novel antimicrobial compounds against MRSA and possibly other multidrug resistant bacteria.

Citations

Citations to this article as recorded by

Synthetic peptide (DP1) functionalized graphene oxide: A biocompatible nanoformulation with broad-spectrum antibacterial and antibiofilm activity
Shubhi Joshi, Jatin Chadha, Kusum Harjai, Gaurav Verma, Avneet Saini
FlatChem.2024; 44: 100626. CrossRef
Cathelicidin-BF regulates the AMPK/SIRT1/NF-κB pathway to ameliorate murine osteoarthritis: In vitro and in vivo studie
Hao Zhou, Linfang Zou, Hui Ren, Zhenyu Shen, Yuanqu Lin, Haikang Cai, Jingdong Zhang
International Immunopharmacology.2024; 134: 112201. CrossRef
Flow-Based Fmoc-SPPS Preparation and SAR Study of Cathelicidin-PY Reveals Selective Antimicrobial Activity
Shama Dissanayake, Junming He, Sung H. Yang, Margaret A. Brimble, Paul W. R. Harris, Alan J. Cameron
Molecules.2023; 28(4): 1993. CrossRef
Rational Design of RN15m4 Cathelin Domain-Based Peptides from Siamese Crocodile Cathelicidin Improves Antimicrobial Activity
Nisachon Jangpromma, Monruedee Konkchaiyaphum, Arpaporn Punpad, Sirinthip Sosiangdi, Sakda Daduang, Sompong Klaynongsruang, Anupong Tankrathok
Applied Biochemistry and Biotechnology.2023; 195(2): 1096. CrossRef
Past, Present, and Future of Naturally Occurring Antimicrobials Related to Snake Venoms
Nancy Oguiura, Leonardo Sanches, Priscila V. Duarte, Marcos A. Sulca-López, Maria Terêsa Machini
Animals.2023; 13(4): 744. CrossRef
Bibliometric Analysis of Literature in Snake Venom-Related Research Worldwide (1933–2022)
Fajar Sofyantoro, Donan Satria Yudha, Kenny Lischer, Tri Rini Nuringtyas, Wahyu Aristyaning Putri, Wisnu Ananta Kusuma, Yekti Asih Purwestri, Respati Tri Swasono
Animals.2022; 12(16): 2058. CrossRef
Antimicrobial peptide GL13K immobilized onto SLA-treated titanium by silanization: antibacterial effect against methicillin-resistant Staphylococcus aureus (MRSA)
Yusang Li, Ruiying Chen, Fushi Wang, Xinjie Cai, Yining Wang
RSC Advances.2022; 12(11): 6918. CrossRef
Ab initio Designed Antimicrobial Peptides Against Gram-Negative Bacteria
Shravani S. Bobde, Fahad M. Alsaab, Guangshuan Wang, Monique L. Van Hoek
Frontiers in Microbiology.2021;[Epub] CrossRef
Porcine Myeloid Antimicrobial Peptides: A Review of the Activity and Latest Advances
Shuaibing Shi, Tengfei Shen, Yongqing Liu, Liangliang Chen, Chen Wang, Chengshui Liao
Frontiers in Veterinary Science.2021;[Epub] CrossRef
Hitchhiking with Nature: Snake Venom Peptides to Fight Cancer and Superbugs
Clara Pérez-Peinado, Sira Defaus, David Andreu
Toxins.2020; 12(4): 255. CrossRef
Identification of the first Crocodylus siamensis cathelicidin gene and RN15 peptide derived from cathelin domain exhibiting antibacterial activity
Anupong Tankrathok, Arpaporn Punpad, Monrudee Kongchaiyapoom, Sirinthip Sosiangdi, Nisachon Jangpromma, Sakda Daduang, Sompong Klaynongsruang
Biotechnology and Applied Biochemistry.2019; 66(2): 142. CrossRef
Characterization of the Bioactivity and Mechanism of Bactenecin Derivatives Against Food-Pathogens
Changbao Sun, Liya Gu, Muhammad Altaf Hussain, Lijun Chen, Li Lin, Haimei Wang, Shiyue Pang, Chenggang Jiang, Zhanmei Jiang, Juncai Hou
Frontiers in Microbiology.2019;[Epub] CrossRef
Natural Occurrence in Venomous Arthropods of Antimicrobial Peptides Active against Protozoan Parasites
Elias Ferreira Sabiá Júnior, Luis Felipe Santos Menezes, Israel Flor Silva de Araújo, Elisabeth Ferroni Schwartz
Toxins.2019; 11(10): 563. CrossRef
The Most Important Herbs Used in the Treatment of Sexually Transmitted Infections in Traditional Medicine
Mohammadreza Nazer, Saber Abbaszadeh, Mohammd Darvishi, Abdolreza Kheirollahi, Somayeh Shahsavari, Mona Moghadasi
Sudan Journal of Medical Sciences.2019;[Epub] CrossRef
Simplified Head-to-Tail Cyclic Polypeptides as Biomaterial-Associated Antimicrobials with Endotoxin Neutralizing and Anti-Inflammatory Capabilities
Na Dong, Chensi Wang, Xinran Li, Yuming Guo, Xiaoli Li
International Journal of Molecular Sciences.2019; 20(23): 5904. CrossRef
Sedation with medicinal plants: A review of medicinal plants with sedative properties in Iranian ethnoblotanical documents
Fariba Bahmani, Hamidreza Kazemeini, Fatemeh Hoseinzadeh-Chahkandak, Tahereh Farkhondeh, mahshid sedaghat
Plant Biotechnology Persa.2019; 1(1): 13. CrossRef
A review of the most important medicinal herbs affecting giardiasis
Mohamad Reza Nazer, Saber Abbaszadeh, Khatereh Anbari, Morteza Shams
Journal of Herbmed Pharmacology.2019; 8(2): 78. CrossRef
Antimicrobial peptide similarity and classification through rough set theory using physicochemical boundaries
Kyle Boone, Kyle Camarda, Paulette Spencer, Candan Tamerler
BMC Bioinformatics.2018;[Epub] CrossRef
A Recombinant Snake Cathelicidin Derivative Peptide: Antibiofilm Properties and Expression in Escherichia coli
Mercedeh Tajbakhsh, Maziar Mohammad Akhavan, Fatemeh Fallah, Abdollah Karimi
Biomolecules.2018; 8(4): 118. CrossRef

First
Prev
Page of 1
Next
Last

Search