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Review
Trans-acting regulators of ribonuclease activity
Jaejin Lee , Minho Lee , Kangseok Lee
J. Microbiol. 2021;59(4):341-359.   Published online March 29, 2021
DOI: https://doi.org/10.1007/s12275-021-0650-6
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AbstractAbstract
RNA metabolism needs to be tightly regulated in response to changes in cellular physiology. Ribonucleases (RNases) play an essential role in almost all aspects of RNA metabolism, including processing, degradation, and recycling of RNA molecules. Thus, living systems have evolved to regulate RNase activity at multiple levels, including transcription, post-transcription, post-translation, and cellular localization. In addition, various trans-acting regulators of RNase activity have been discovered in recent years. This review focuses on the physiological roles and underlying mechanisms of trans-acting regulators of RNase activity.

Citations

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  • Comparative Transcriptomic Analysis of Flagellar-Associated Genes in Salmonella Typhimurium and Its rnc Mutant
    Seungmok Han, Ji-Won Byun, Minho Lee
    Journal of Microbiology.2024; 62(1): 33.     CrossRef
  • Insights into the metabolism, signaling, and physiological effects of 2’,3’-cyclic nucleotide monophosphates in bacteria
    Nick J. Marotta, Emily E. Weinert
    Critical Reviews in Biochemistry and Molecular Biology.2023; 58(2-6): 118.     CrossRef
  • Relaxed Cleavage Specificity of Hyperactive Variants of Escherichia coli RNase E on RNA I
    Dayeong Bae, Hana Hyeon, Eunkyoung Shin, Ji-Hyun Yeom, Kangseok Lee
    Journal of Microbiology.2023; 61(2): 211.     CrossRef
  • Regulator of RNase E activity modulates the pathogenicity of Salmonella Typhimurium
    Jaejin Lee, Eunkyoung Shin, Ji-Hyun Yeom, Jaeyoung Park, Sunwoo Kim, Minho Lee, Kangseok Lee
    Microbial Pathogenesis.2022; 165: 105460.     CrossRef

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