- Denitrifying Woodchip Bioreactors: A Microbial Solution for Nitrate in Agricultural Wastewater—A Review
-
Sua Lee , Min Cho , Michael J. Sadowsky , Jeonghwan Jang
-
J. Microbiol. 2023;61(9):791-805. Published online August 18, 2023
-
DOI: https://doi.org/10.1007/s12275-023-00067-z
-
-
82
View
-
0
Download
-
3
Web of Science
-
3
Crossref
-
 Abstract
-
Nitrate (
NO3
−) is highly water-soluble and considered to be the main nitrogen pollutants leached from agricultural soils. Its
presence in aquatic ecosystems is reported to cause various environmental and public health problems. Bioreactors containing
microbes capable of transforming NO3
− have been proposed as a means to remediate contaminated waters. Woodchip bioreactors
(WBRs) are continuous flow, reactor systems located below or above ground. Below ground systems are comprised
of a trench filled with woodchips, or other support matrices. The nitrate present in agricultural drainage wastewater passing
through the bioreactor is converted to harmless dinitrogen gas (
N2) via the action of several bacteria species. The WBR has
been suggested as one of the most cost-effective NO3
−-removing strategy among several edge-of-field practices, and has been
shown to successfully remove NO3
− in several field studies. NO3
− removal in the WBR primarily occurs via the activity of
denitrifying microorganisms via enzymatic reactions sequentially reducing NO3
− to N2.
While previous woodchip bioreactor
studies have focused extensively on its engineering and hydrological aspects, relatively fewer studies have dealt with the
microorganisms playing key roles in the technology. This review discusses NO3
− pollution cases originating from intensive
farming practices and N-cycling microbial metabolisms which is one biological solution to remove NO3
− from agricultural
wastewater. Moreover, here we review the current knowledge on the physicochemical and operational factors affecting
microbial metabolisms resulting in removal of NO3
− in WBR, and perspectives to enhance WBR performance in the future.
-
Citations
Citations to this article as recorded by  -
Complete genome sequence of
Neobacillus
sp. strain OS1-2, a denitrifying bacterium isolated from apple orchard soil
Jinwoo Ahn, Jeonghwan Jang, Elinne Becket
Microbiology Resource Announcements.2025;[Epub] CrossRef - Dissimilatory nitrate reductions in soil Neobacillus and Bacillus strains under aerobic condition
Seohyun Ahn, Min Cho, Michael J. Sadowsky, Jeonghwan Jang
Journal of Microbiology.2025; 63(2): e2411019. CrossRef - Mn-oxidizing microalgae and woodchip-denitrifying bioreactor system for recovering manganese and removing nitrogen from electrolytic manganese metal industrial tailwater
Xinyue Gong, Qin Peng, Ruixin Jiang, Na Yang, Cijun Xing, Rui Wang
Journal of Hazardous Materials.2025; 488: 137383. CrossRef
- Microbial source tracking using metagenomics and other new technologies
-
Shahbaz Raza , Jungman Kim , Michael J. Sadowsky , Tatsuya Unno
-
J. Microbiol. 2021;59(3):259-269. Published online February 10, 2021
-
DOI: https://doi.org/10.1007/s12275-021-0668-9
-
-
73
View
-
0
Download
-
14
Web of Science
-
14
Crossref
-
Abstract
-
The environment is under siege from a variety of pollution
sources. Fecal pollution is especially harmful as it disperses
pathogenic bacteria into waterways. Unraveling origins of
mixed sources of fecal bacteria is difficult and microbial
source tracking (MST) in complex environments is still a
daunting task. Despite the challenges, the need for answers
far outweighs the difficulties experienced. Advancements in
qPCR and next generation sequencing (NGS) technologies
have shifted the traditional culture-based MST approaches
towards culture independent technologies, where communitybased
MST is becoming a method of choice. Metagenomic
tools may be useful to overcome some of the limitations of
community-based MST methods as they can give deep insight
into identifying host specific fecal markers and their association
with different environments. Adoption of machine
learning (ML) algorithms, along with the metagenomic based
MST approaches, will also provide a statistically robust and
automated platform. To compliment that, ML-based approaches
provide accurate optimization of resources. With the
successful application of ML based models in disease prediction,
outbreak investigation and medicine prescription,
it would be possible that these methods would serve as a
better surrogate of traditional MST approaches in future.
-
Citations
Citations to this article as recorded by - Universal microbial indicators provide surveillance of sewage contamination in harbours worldwide
Sandra L. McLellan, Anthony Chariton, Annachiara Codello, Jill S. McClary-Gutierrez, Melissa K. Schussman, Ezequiel M. Marzinelli, Judith M. O’Neil, Eric J. Schott, Jennifer L. Bowen, Joe H. Vineis, Lois Maignien, Clarisse Lemonnier, Morgan Perennou, Kare
Nature Water.2024; 2(11): 1061. CrossRef - Integrating molecular microbial methods to improve faecal pollution management in rivers with designated bathing waters
Esther Karunakaran, Rick Battarbee, Simon Tait, Bruno Melo Brentan, Cathal Berney, James Grinham, Maria Angeles Herrero, Ronex Omolo, Isabel Douterelo
Science of The Total Environment.2024; 912: 168565. CrossRef - Application of Pan-Omics Technologies in Research on Important Economic Traits for Ruminants
Zhendong Gao, Ying Lu, Mengfei Li, Yuqing Chong, Jieyun Hong, Jiao Wu, Dongwang Wu, Dongmei Xi, Weidong Deng
International Journal of Molecular Sciences.2024; 25(17): 9271. CrossRef - decOM: similarity-based microbial source tracking of ancient oral samples using k-mer-based methods
Camila Duitama González, Riccardo Vicedomini, Téo Lemane, Nicolas Rascovan, Hugues Richard, Rayan Chikhi
Microbiome.2023;[Epub] CrossRef - Unraveling the influence of human fecal pollution on antibiotic resistance gene levels in different receiving water bodies using crAssphage indicator gene
Zeyou Chen, Yujing Duan, Lichun Yin, Ying Chen, Yingang Xue, Xiaolong Wang, Daqing Mao, Yi Luo
Journal of Hazardous Materials.2023; 442: 130005. CrossRef - Have genetic targets for faecal pollution diagnostics and source tracking revolutionized water quality analysis yet?
Katalin Demeter, Rita Linke, Elisenda Ballesté, Georg Reischer, René E Mayer, Julia Vierheilig, Claudia Kolm, Margaret E Stevenson, Julia Derx, Alexander K T Kirschner, Regina Sommer, Orin C Shanks, Anicet R Blanch, Joan B Rose, Warish Ahmed, Andreas H Fa
FEMS Microbiology Reviews.2023;[Epub] CrossRef - Comparative Microbial Community Analysis of Fur Seals and Aquaculture Salmon Gut Microbiomes in Tasmania
Erin D’Agnese, Ryan J. McLaughlin, Mary-Anne Lea, Esteban Soto, Woutrina A. Smith, John P. Bowman
Oceans.2023; 4(2): 200. CrossRef - Strategies for Monitoring Microbial Life in Beach Sand for Protection of Public Health
João Brandão, Elisabete Valério, Chelsea Weiskerger, Cristina Veríssimo, Konstantina Sarioglou, Monika Novak Babič, Helena M. Solo-Gabriele, Raquel Sabino, Maria Teresa Rebelo
International Journal of Environmental Research and Public Health.2023; 20(9): 5710. CrossRef - Microbial Source Tracking: An Emerging Technology for Microbial Water Quality Assessment: A Review
Job, O.S., Bala, J.D., Abdulraham, A.A., Friday, N.N., Ibekie, S.A., Tsebam, C.J, Abudullahi, D.
UMYU Journal of Microbiology Research (UJMR).2023; 8(1): 109. CrossRef - Local and Environmental Reservoirs ofSalmonella entericaAfter Hurricane Florence Flooding
Yuqing Mao, Mohamed Zeineldin, Moiz Usmani, Antarpreet Jutla, Joanna L. Shisler, Rachel J. Whitaker, Thanh H. Nguyen
GeoHealth.2023;[Epub] CrossRef - Humans and Hoofed Livestock Are the Main Sources of Fecal Contamination of Rivers Used for Crop Irrigation: A Microbial Source Tracking Approach
Constanza Díaz-Gavidia, Carla Barría, Daniel L. Weller, Marilia Salgado-Caxito, Erika M. Estrada, Aníbal Araya, Leonardo Vera, Woutrina Smith, Minji Kim, Andrea I. Moreno-Switt, Jorge Olivares-Pacheco, Aiko D. Adell
Frontiers in Microbiology.2022;[Epub] CrossRef - Interfacing Machine Learning and Microbial Omics: A Promising Means to Address Environmental Challenges
James M. W. R. McElhinney, Mary Krystelle Catacutan, Aurelie Mawart, Ayesha Hasan, Jorge Dias
Frontiers in Microbiology.2022;[Epub] CrossRef - Role of gene sequencing for the diagnosis, tracking and prevention of bacterial infections
Renu Kumari, Benu Dhawan
Journal of The Academy of Clinical Microbiologists.2022; 24(S1): 8. CrossRef - Omics-based microbiome analysis in microbial ecology: from sequences to information
Jang-Cheon Cho
Journal of Microbiology.2021; 59(3): 229. CrossRef
- REVIEW] Current understanding of microbiota- and dietary-therapies for treating inflammatory bowel disease
-
Taekil Eom , Yong Sung Kim , Chang Hwan Choi , Michael J. Sadowsky , Tatsuya Unno
-
J. Microbiol. 2018;56(3):189-198. Published online February 28, 2018
-
DOI: https://doi.org/10.1007/s12275-018-8049-8
-
-
81
View
-
0
Download
-
89
Crossref
-
Abstract
-
Inflammatory bowel disease (IBD) is a result of chronic inflammation
caused, in some part, by dysbiosis of intestinal
microbiota, mainly commensal bacteria. Gut dysbiosis can
be caused by multiple factors, including abnormal immune
responses which might be related to genetic susceptibility,
infection, western dietary habits, and administration of antibiotics.
Consequently, the disease itself is characterized as
having multiple causes, etiologies, and severities. Recent studies
have identified > 200 IBD risk loci in the host. It has been
postulated that gut microbiota interact with these risk loci
result
ing in dysbiosis, and this subsequently leads to the development
of IBD. Typical gut microbiota in IBD patients
are characterized with decrease in species richness and many
of the commensal, and beneficial, fecal bacteria such as Firmicutes
and Bacteroidetes and an increase or bloom of Proteobacteria.
However, at this time, cause and effect relationships
have not been rigorously established. While treatments
of IBD usually includes medications such as corticosteroids,
5-aminosalicylates, antibiotics, immunomodulators, and anti-
TNF agents, restoration of gut dysbiosis seems to be a safer
and more sustainable approach. Bacteriotherapies (now called
microbiota therapies) and dietary interventions are effective
way to modulate gut microbiota. In this review, we summarize
factors involved in IBD and studies attempted to treat IBD
with probiotics. We also discuss the potential use of microbiota
therapies as one promising approach in treating IBD.
As therapies based on the modulation of gut microbiota becomes
more common, future studies should include individual
gut microbiota differences to develop personalized therapy
for IBD.
-
Citations
Citations to this article as recorded by - Benzo[a]Pyrene Induces Pyroptotic Colon Damage and Gut Dysbacteriosis by Activating Aryl Hydrocarbon Receptor
Yingyu Jia, Yao Meng, Zhulin Wang, Hao Li, Jianke Li, Li Yuan
Food Biophysics.2025;[Epub] CrossRef - Patient–donor similarity and donor-derived species contribute to the outcome of fecal microbiota transplantation for ulcerative colitis
Dai Ishikawa, Hikaru Watanabe, Kei Nomura, Xiaochen Zhang, Takafumi Maruyama, Rina Odakura, Masao Koma, Tomoyoshi Shibuya, Taro Osada, Shinji Fukuda, Taku Nakahara, Jun Terauchi, Akihito Nagahara, Takuji Yamada
Journal of Crohn's and Colitis.2025;[Epub] CrossRef - Sturgeon cartilage-derived chondroitin sulfate exhibited anti-inflammatory activity against dextran sulfate sodium-induced colitis
via modification of gut microbiota
Ruiyun Wu, Zixin Han, Zhenyu Wang, Pinglan Li, Nan Shang
Food Science and Human Wellness.2025; 14(4): 9250227. CrossRef - Intestinal microecology in pediatric surgery-related gastrointestinal diseases: Current insights and future perspectives
Yuqing Wu, Suolin Li, Lin Liu, Xiaoyi Zhang, Jiaxun Lv, Qinqin Li, Yingchao Li
Journal of Pediatric Surgery Open.2024; 6: 100134. CrossRef - Gut Microbiome as a Target of Intervention in Inflammatory Bowel Disease Pathogenesis and Therapy
Helal F. Hetta, Yasmin N. Ramadan, Ahmad A. Alharbi, Shomokh Alsharef, Tala T. Alkindy, Alanoud Alkhamali, Abdullah S. Albalawi, Hussein El Amin
Immuno.2024; 4(4): 400. CrossRef - Intestinal and hepatic benefits of BBR-EVO on DSS-induced experimental colitis in mice
Wenjia Wang, Yiheng Han, Wen Yin, Qiaozhi Wang, Yi Wu, Maobo Du
Frontiers in Microbiology.2024;[Epub] CrossRef - Exploring the Connections: Autophagy, Gut Microbiota, and Inflammatory Bowel Disease Pathogenesis
Arunkumar Subramanian, Afrarahamed J, Tamilanban T, Vinoth Kumarasamy, M Yasmin Begum, Mahendran Sekar, Vetriselvan Subramaniyan, Ling Shing Wong, Adel Al Fatease
Journal of Inflammation Research.2024; Volume 17: 10453. CrossRef - Network Analysis of Gut Microbial Communities Reveals Key Reason for Quercetin Protects against Colitis
Yanan Lv, Jing Peng, Xiaoyu Ma, Zeyi Liang, Ghasem Hosseini Salekdeh, Qunhua Ke, Wenxiang Shen, Zuoting Yan, Hongsheng Li, Shengyi Wang, Xuezhi Ding
Microorganisms.2024; 12(10): 1973. CrossRef - Analysis of the Preventive Effect of Lonicera caerulea Pomace and Its Isolated Components on Colitis in Mice Based on Gut Microbiota and Serum Metabolomics
Zinuo Zhou, Xinwen Huang, Baixi Zhang
Antioxidants.2024; 13(12): 1478. CrossRef - Stachyose Exerts Anticolitis Efficacy by Re-balancing Treg/Th17 and Activating the Butyrate-Derived PPARγ Signaling Pathway
Ningning He, Kaiwei Chen, Shengnan Yu, Luwen Cui, Son Hai Vu, Samil Jung, Myeong-sok Lee, Shangyong Li
Journal of Agricultural and Food Chemistry.2024; 72(21): 12171. CrossRef - Probiotic Microorganisms in Inflammatory Bowel Diseases: Live Biotherapeutics as Food
Emanuelle Natalee Santos, Karina Teixeira Magalhães-Guedes, Fernando Elias de Melo Borges, Danton Diego Ferreira, Daniele Ferreira da Silva, Pietro Carlos Gonçalves Conceição, Ana Katerine de Carvalho Lima, Lucas Guimarães Cardoso, Marcelo Andrés Umsza-Gu
Foods.2024; 13(24): 4097. CrossRef - Raffinose Ameliorates DSS-Induced Colitis in Mice by Modulating Gut Microbiota and Targeting the Inflammatory TLR4–MyD88–NF-κB Signaling Pathway
Peng Zhang, Yuyang Xue, Zhengyu Cao, Yaya Guo, Xiaotong Pang, Cheng Chen, Wenju Zhang
Foods.2024; 13(12): 1849. CrossRef - Fecal Microbiota Transplantation: Indications, Methods, and Challenges
Jee Young Lee, Yehwon Kim, Jiyoun Kim, Jiyeun Kate Kim
Journal of Microbiology.2024; 62(12): 1057. CrossRef - Ethyl acetate extract of Terminalia chebula alleviates DSS-induced ulcerative colitis in C57BL/6 mice
Wan-Rong Dong, Yao-Yao Li, Tian-Tian Liu, Gao Zhou, Yu-Xin Chen
Frontiers in Pharmacology.2023;[Epub] CrossRef - A Novel Polysaccharide Separated from Panax Notoginseng Residue Ameliorates Restraint Stress‐ and Lipopolysaccharide‐induced Enteritis in Mice
Bi Luo, Fan Yang, Peng Chen, Hao‐Yu Zuo, Yun‐Fei Liang, Ming‐Hua Xian, Nan Tang, Guo‐En Wang
Chemistry & Biodiversity.2023;[Epub] CrossRef - Gut microbiome, metabolome, host immunity associated with inflammatory bowel disease and intervention of fecal microbiota transplantation
Rongrong Wu, Rui Xiong, Yan Li, Junru Chen, Ru Yan
Journal of Autoimmunity.2023; 141: 103062. CrossRef - Current advances in the anti-inflammatory effects and mechanisms of natural polysaccharides
Dan Yuan, Chao Li, Qiang Huang, Xiong Fu, Hao Dong
Critical Reviews in Food Science and Nutrition.2023; 63(22): 5890. CrossRef -
Poria cocos oligosaccharides ameliorate dextran sodium sulfate-induced colitis mice by regulating gut microbiota dysbiosis
Ke Lan, Huabing Yang, Junping Zheng, Haiming Hu, Tianxiang Zhu, Xiaojuan Zou, Baifei Hu, Hongtao Liu
Food & Function.2023; 14(2): 857. CrossRef - Chiral coating-mediated interactions of bacteria with diverse biointerfaces
Hejin Jiang, Rui Liu, Ying Liu, Huilong Luo, Zhenping Cao, Jinyao Liu
Science China Chemistry.2023; 66(12): 3594. CrossRef - Recent Advances in the Nanoshells Approach for Encapsulation of Single Probiotics
Cheng Chen, Ziyu Zhu
Drug Design, Development and Therapy.2023; Volume 17: 2763. CrossRef - Interplay of broccoli/broccoli sprout bioactives with gut microbiota in reducing inflammation in inflammatory bowel diseases
Johanna Holman, Molly Hurd, Peter L. Moses, Gary M. Mawe, Tao Zhang, Suzanne L. Ishaq, Yanyan Li
The Journal of Nutritional Biochemistry.2023; 113: 109238. CrossRef - Lonicera caerulea Pomace Alleviates DSS-Induced Colitis via Intestinal Barrier Improvement and Gut Microbiota Modulation
Baixi Zhang, Xinwen Huang, Lijuan Niu, Xuemei Chen, Bo Hu, Xiaoshu Tang
Foods.2023; 12(18): 3329. CrossRef - The Combined Use of SCD Probiotics and Tauroursodeoksikolik Asit (TUDCA) is More Effective in Controlling Anxiety-Like Behavior in Aged Rats
Taha CEYLANİ, Hikmet Taner TEKER
Bitlis Eren Üniversitesi Fen Bilimleri Dergisi.2023; 12(1): 242. CrossRef - The Possible Role of Probiotic Supplementation in Inflammation: A Narrative Review
Alessandro Colletti, Marzia Pellizzato, Arrigo Francesco Cicero
Microorganisms.2023; 11(9): 2160. CrossRef - A polysaccharide from Allium tenuissimum L. flowers relieves ulcerative colitis by regulating the inflammatory signaling pathway and gut microbiota
Yan Zhang, Siyu Yu, Jia Liu, Ying Liu, Jie Luo, Yong Liu
Food & Function.2023; 14(14): 6582. CrossRef - Molecular mechanisms of Huanglian jiedu decoction on ulcerative colitis based on network pharmacology and molecular docking
Jing Yang, Chaotao Tang, Ruiri Jin, Bixia Liu, Peng Wang, Youxiang Chen, Chunyan Zeng
Scientific Reports.2022;[Epub] CrossRef - Effects of β-glucan, probiotics, and synbiotics on obesity-associated colitis and hepatic manifestations in C57BL/6J mice
Vuong Vu, Karthika Muthuramalingam, Vineet Singh, Changlim Hyun, Young Mee Kim, Tatsuya Unno, Moonjae Cho
European Journal of Nutrition.2022; 61(2): 793. CrossRef - Human umbilical cord-derived mesenchymal stem cells ameliorate experimental colitis by normalizing the gut microbiota
Fan Yang, Beibei Ni, Qiuli Liu, Fangping He, Li Li, Xuemei Zhong, Xiaofan Zheng, Jianxi Lu, Xiaoyan Chen, Huizhu Lin, Ruixuan Xu, Yizhan He, Qi Zhang, Xiaoguang Zou, Wenjie Chen
Stem Cell Research & Therapy.2022;[Epub] CrossRef - The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism
Canxia He, Mingfei Gao, Xiaohong Zhang, Peng Lei, Haitao Yang, Yanping Qing, Lina Zhang
Frontiers in Nutrition.2022;[Epub] CrossRef - The Attenuation of Chronic Ulcerative Colitis by (R)‐salbutamol in Repeated DSS‐Induced Mice
Liangjun Deng, Haihua Guo, Shanping Wang, Xiaoming Liu, Yue Lin, Rui Zhang, Wen Tan, Ivan Srejovic
Oxidative Medicine and Cellular Longevity.2022;[Epub] CrossRef - CROHN’S DISEASE: A REVIEW ON EPIDEMIOLOGY, DIAGNOSIS AND THERAPEUTIC MANAGEMENT
Mohammad Mukim, Mohit Chaturvedi, Rakesh Patel, Supriya Roy, Pratishtha Sharma, Varunesh Chaturvedi, Saloni Goyal, Mohsina F. Patewkar
Indian Drugs.2022; 59(09): 16. CrossRef - Poly‐γ‐Glutamic Acid Microgel‐Encapsulated Probiotics with Gastric Acid Resistance and Smart Inflammatory Factor Targeted Delivery Performance to Ameliorate Colitis
Rui Wang, Kun Guo, Weijie zhang, Yineng He, Kai Yang, Qian Chen, Liang Yang, Zhengao Di, Jiangkai Qiu, Peng Lei, Yian Gu, Zhengshan Luo, Xiaoqi Xu, Zongqi Xu, Xiaohai Feng, Sha Li, Ziyi Yu, Hong Xu
Advanced Functional Materials.2022;[Epub] CrossRef - Probiotic human alcohol dehydrogenase-4 expressing bacteria protects from diet-induced obesity and metabolic impairment: a new concept of disease prevention
Rajnish Prakash Singh, Max Kolton, Mayan Boker, Noy Bar David, Stefan Green, Aharon Helman, Oren Tirosh, Zvi Hayouka
Exploration of Digestive Diseases.2022; : 118. CrossRef - (RS)-bambuterol and its enantiomers: Potential improvement of (R)-bambuterol in mice with colitis
Liangjun Deng, Shanping Wang, Haihua Guo, Xiaoming Liu, Xinfeng Zou, Rui Zhang, Yue Lin, Wen Tan
International Immunopharmacology.2022; 103: 108501. CrossRef - Chitosan Oligosaccharides Alleviate Colitis by Regulating Intestinal Microbiota and PPARγ/SIRT1-Mediated NF-κB Pathway
Congcong Guo, Yue Zhang, Tao Ling, Chongjie Zhao, Yanru Li, Meng Geng, Sailun Gai, Wei Qi, Xuegang Luo, Liehuan Chen, Tongcun Zhang, Nan Wang
Marine Drugs.2022; 20(2): 96. CrossRef - Environmentality in biomedicine: microbiome research and the perspectival body
Joana Formosinho, Adam Bencard, Louise Whiteley
Studies in History and Philosophy of Science.2022; 91: 148. CrossRef - Glucocorticosteroids and the Risk of NAFLD in Inflammatory Bowel Disease
Sara Jarmakiewicz-Czaja, Aneta Sokal, Piotr Pardak, Rafał Filip, Alessandro Granito
Canadian Journal of Gastroenterology and Hepatology.2022; 2022: 1. CrossRef - Major yolk protein from sea cucumber (Stichopus japonicus) attenuates acute colitis via regulation of microbial dysbiosis and inflammatory responses
Jianhui Feng, Lina Zhang, Xue Tang, Wei Hu, Peng Zhou
Food Research International.2022; 151: 110841. CrossRef - Anemoside B4 protects against chronic relapsing colitis in mice by modulating inflammatory response, colonic transcriptome and the gut microbiota
Qian Han, Li-rong Deng, Min Zou, Hua-zheng Tang, Chang-yin Huang, Fang-jun Chen, Brian Tomlinson, Yan-hong Li
Phytomedicine.2022; 106: 154416. CrossRef - Alginate Oligosaccharides Ameliorate DSS-Induced Colitis through Modulation of AMPK/NF-κB Pathway and Intestinal Microbiota
Yue Zhang, Congcong Guo, Yanru Li, Xianlei Han, Xuegang Luo, Liehuan Chen, Tongcun Zhang, Nan Wang, Weiming Wang
Nutrients.2022; 14(14): 2864. CrossRef - Gut microbiota in antiviral strategy from bats to humans: a missing link in COVID-19
Jia Luo, Shan Liang, Feng Jin
Science China Life Sciences.2021; 64(6): 942. CrossRef - Curcumin modulates gut microbiota and improves renal function in rats with uric acid nephropathy
Xueling Xu, Huifang Wang, Dandan Guo, Xiaofei Man, Jun Liu, Junying Li, Congjuan Luo, Ming Zhang, Li Zhen, Xuemei Liu
Renal Failure.2021; 43(1): 1063. CrossRef - Prebiotics, Probiotics, Synbiotics, Paraprobiotics and Postbiotic Compounds in IBD
Adrian Martyniak, Aleksandra Medyńska-Przęczek, Andrzej Wędrychowicz, Szymon Skoczeń, Przemysław J. Tomasik
Biomolecules.2021; 11(12): 1903. CrossRef - Mitochondrial Metabolism in the Intestinal Stem Cell Niche—Sensing and Signaling in Health and Disease
Elisabeth Urbauer, Eva Rath, Dirk Haller
Frontiers in Cell and Developmental Biology.2021;[Epub] CrossRef - GB1a Ameliorates Ulcerative Colitis via Regulation of the NF-κB and Nrf2 Signaling Pathways in an Experimental Model
Yuanyuan Yu, Congmin Zheng, Xu Lu, Changsheng Deng, Qin Xu, Wenfeng Guo, Qingye Wu, Qi Wang, Changhui Liu, Xinan Huang, Jianping Song
Frontiers in Medicine.2021;[Epub] CrossRef - Dietary patterns, food groups and nutrients in Crohn’s disease: associations with gut and systemic inflammation
S. Ali Naqvi, Lorian M. Taylor, Remo Panaccione, Subrata Ghosh, Herman W. Barkema, Naomi Hotte, Nusrat Shommu, Sandeep Kaur, Raylene A. Reimer, Karen L. Madsen, Maitreyi Raman
Scientific Reports.2021;[Epub] CrossRef - Ginger Alleviates DSS-Induced Ulcerative Colitis Severity by Improving the Diversity and Function of Gut Microbiota
Shanshan Guo, Wenye Geng, Shan Chen, Li Wang, Xuli Rong, Shuocun Wang, Tingfang Wang, Liyan Xiong, Jinghua Huang, Xiaobin Pang, Yiming Lu
Frontiers in Pharmacology.2021;[Epub] CrossRef - Long-term and continuous administration of Bacillus subtilis during remission effectively maintains the remission of inflammatory bowel disease by protecting intestinal integrity, regulating epithelial proliferation, and reshaping microbial structure and
Yongqiang Liu, Fang Yin, Linsheng Huang, Hongfei Teng, Tongyi Shen, Huanlong Qin
Food & Function.2021; 12(5): 2201. CrossRef - Cereal Vinegar Sediment Alleviates Spontaneous Ulcerative Colitis in Il‐10 Deficient Mice
Yan Geng, Yuanjia Yue, Qijie Guan, Yilin Ren, Lin Guo, Yifei Fan, Zhen‐Ming Lu, Jin‐Song Shi, Zheng‐Hong Xu
Molecular Nutrition & Food Research.2021;[Epub] CrossRef - Impact of 2′-Fucosyllactose on Gut Microbiota Composition in Adults with Chronic Gastrointestinal Conditions: Batch Culture Fermentation Model and Pilot Clinical Trial Findings
Jennifer Joan Ryan, Andrea Monteagudo-Mera, Nikhat Contractor, Glenn R. Gibson
Nutrients.2021; 13(3): 938. CrossRef - Effects of Anti-Inflammatory Treatment and Surgical Intervention on Endothelial Glycocalyx, Peripheral and Coronary Microcirculatory Function and Myocardial Deformation in Inflammatory Bowel Disease Patients: A Two-Arms Two-Stage Clinical Trial
Charilaos Triantafyllou, Maria Nikolaou, Ignatios Ikonomidis, Giorgos Bamias, Dimitrios Kouretas, Ioanna Andreadou, Maria Tsoumani, John Thymis, Ioannis Papaconstantinou
Diagnostics.2021; 11(6): 993. CrossRef - Bacteria-Based Microdevices for the Oral Delivery of Macromolecules
Zhenping Cao, Sisi Lin, Jinyao Liu
Pharmaceutics.2021; 13(10): 1610. CrossRef - EEG Changes Related to Gut Dysbiosis in Diabetes—Review
Roxana Toderean, Mihai Dimian, Claudiu Cobuz
Applied Sciences.2021; 11(24): 11871. CrossRef - The Combined Beneficial Effects of Postbiotic Butyrate on Active Vitamin D3-Orchestrated Innate Immunity to Salmonella Colitis
Fu-Chen Huang, Shun-Chen Huang
Biomedicines.2021; 9(10): 1296. CrossRef - Protective Effects of Shrimp Peptide on Dextran Sulfate Sodium-Induced Colitis in Mice
Xingwei Xiang, Qihong Jiang, Wan Shao, Jinhong Li, Yufang Zhou, Lin Chen, Shanggui Deng, Bin Zheng, Yufeng Chen
Frontiers in Nutrition.2021;[Epub] CrossRef - Polymerization‐Mediated Multifunctionalization of Living Cells for Enhanced Cell‐Based Therapy
Chao Pan, Juanjuan Li, Weiliang Hou, Sisi Lin, Lu Wang, Yan Pang, Yufeng Wang, Jinyao Liu
Advanced Materials.2021;[Epub] CrossRef - High Red Meat Intake Exacerbates Dextran Sulfate-Induced Colitis by Altering Gut Microbiota in Mice
Dan-ping Li, Min Cui, Fang Tan, Xiao-yan Liu, Ping Yao
Frontiers in Nutrition.2021;[Epub] CrossRef - Dihydroartemisinin ameliorates dextran sulfate sodium induced inflammatory bowel diseases in mice
Zili Lei, Yanhong Yang, Shaomin Liu, Yuting Lei, Lanxiang Yang, Xueying Zhang, Wanwan Liu, Huijuan Wu, Changyuan Yang, Jiao Guo
Bioorganic Chemistry.2020; 100: 103915. CrossRef - Manipulating resident microbiota to enhance regulatory immune function to treat inflammatory bowel diseases
Yoshiyuki Mishima, Ryan Balfour Sartor
Journal of Gastroenterology.2020; 55(1): 4. CrossRef - Saikosaponin-d ameliorates dextran sulfate sodium-induced colitis by suppressing NF-κB activation and modulating the gut microbiota in mice
Puze Li, Minna Wu, Wancheng Xiong, Jinsong Li, Yunying An, Jie Ren, Yingguang Xie, Hongfei Xue, Dong Yan, Min Li, Genshen Zhong
International Immunopharmacology.2020; 81: 106288. CrossRef - Exosomes in Inflammatory Bowel Disease: What Have We Learned So Far?
Haichao Wang, Chen Ye, Yaling Wu, Pengyu Yang, Chunqiu Chen, Zhanju Liu, Xiaolei Wang
Current Drug Targets.2020; 21(14): 1448. CrossRef - Aqueous extract of Bruguiera gymnorrhiza leaves protects against dextran sulfate sodium induced ulcerative colitis in mice via suppressing NF-κB activation and modulating intestinal microbiota
Jin-Fen Chen, Dan-Dan Luo, Yin-Si Lin, Yu-Hong Liu, Jia-Zhen Wu, Xiao-Qing Yi, Yan Wu, Qian Zhang, Chang-Jun Gao, Jian Cai, Zi-Ren Su
Journal of Ethnopharmacology.2020; 251: 112554. CrossRef - The Link between Oral and Gut Microbiota in Inflammatory Bowel Disease and a Synopsis of Potential Salivary Biomarkers
Allison Bartlett, Robert G. Gullickson, Rajan Singh, Seungil Ro, Stanley T. Omaye
Applied Sciences.2020; 10(18): 6421. CrossRef - Yogurt enriched to correct intestinal microflora in dysbiosis
V Yu Kontareva, S N Belik, E V Morgul, I F Gorlov, M I Slozhenkina
IOP Conference Series: Earth and Environmental Science.2020; 548(8): 082051. CrossRef - Predicting Microbe-Disease Association by Learning Graph Representations and Rule-Based Inference on the Heterogeneous Network
Xiujuan Lei, Yueyue Wang
Frontiers in Microbiology.2020;[Epub] CrossRef - Consumption of a baked corn and bean snack reduced chronic colitis inflammation in CD-1 mice via downregulation of IL-1 receptor, TLR, and TNF-α associated pathways
Ivan Luzardo-Ocampo, Rocio Campos-Vega, Elvira Gonzalez de Mejia, Guadalupe Loarca-Piña
Food Research International.2020; 132: 109097. CrossRef - The role of a plant-based diet in the pathogenesis, etiology and management of the inflammatory bowel diseases
Charlene S. J. Grosse, Claus T. Christophersen, Amanda Devine, Ian C. Lawrance
Expert Review of Gastroenterology & Hepatology.2020; 14(3): 137. CrossRef - Therapeutic effect of n-butanol fraction of Huang-lian-Jie-du Decoction on ulcerative colitis and its regulation on intestinal flora in colitis mice
Ziwen Yuan, Lihong Yang, Xiaosong Zhang, Peng Ji, Yanming Wei
Biomedicine & Pharmacotherapy.2020; 121: 109638. CrossRef - Anti-inflammatory activity of grapefruit juice in an in vivo model of ulcerative colitis: Comparability studies of unprocessed and bioprocessed juices
Carla Mendes, João Rocha, Rosa Direito, Adelaide Fernandes, Bruno Sepodes, Maria-Eduardo Figueira, Maria H. Ribeiro
Journal of Functional Foods.2019; 63: 103564. CrossRef - Huang-Lian-Jie-Du Decoction Ameliorates Acute Ulcerative Colitis in Mice via Regulating NF-κB and Nrf2 Signaling Pathways and Enhancing Intestinal Barrier Function
Ziwen Yuan, Lihong Yang, Xiaosong Zhang, Peng Ji, Yongli Hua, Yanming Wei
Frontiers in Pharmacology.2019;[Epub] CrossRef - The role of the gut microbiota in the treatment of inflammatory bowel diseases
Ioanna Aggeletopoulou, Christos Konstantakis, Stelios F. Assimakopoulos, Christos Triantos
Microbial Pathogenesis.2019; 137: 103774. CrossRef - Parenteral Nutrition in Patients with Inflammatory Bowel Disease Systematic Review, Meta-Analysis and Meta-Regression
Jose M. Comeche, Iris Comino, Cesare Altavilla, Jose Tuells, Ana Gutierrez-Hervas, Pablo Caballero
Nutrients.2019; 11(12): 2865. CrossRef - Neue medikamentöse Ansätze bei chronisch-entzündlichen Darmerkrankungen
S. Pröbsting, B. Terjung
coloproctology.2019; 41(1): 5. CrossRef - Crohn’s Disease Remission with a Plant-Based Diet: A Case Report
Kelsea Sandefur, Hana Kahleova, Alan N. Desmond, Eden Elfrink, Neal D. Barnard
Nutrients.2019; 11(6): 1385. CrossRef - Intestinal Sensing by Gut Microbiota: Targeting Gut Peptides
Mihai Covasa, Richard W. Stephens, Roxana Toderean, Claudiu Cobuz
Frontiers in Endocrinology.2019;[Epub] CrossRef - Enteral Nutrition in Patients with Inflammatory Bowel Disease. Systematic Review, Meta-Analysis, and Meta-Regression
Jose M. Comeche, Pablo Caballero, Ana Gutierrez-Hervas, Sofia García-Sanjuan, Iris Comino, Cesare Altavilla, Jose Tuells
Nutrients.2019; 11(11): 2657. CrossRef - Endothelial and Cardiac Dysfunction in Inflammatory Bowel Diseases: Does Treatment Modify the Inflammatory Load on Arterial and Cardiac Structure and Function?
Charilaos Triantafyllou, Maria Nikolaou, Ignatios Ikonomidis, Giorgos Bamias, Ioannis Papaconstantinou
Current Vascular Pharmacology.2019; 18(1): 27. CrossRef - Exosome-Induced Regulation in Inflammatory Bowel Disease
Huiting Zhang, Liang Wang, Changyi Li, Yue Yu, Yanlin Yi, Jingyu Wang, Dapeng Chen
Frontiers in Immunology.2019;[Epub] CrossRef - Biointerfacial self-assembly generates lipid membrane coated bacteria for enhanced oral delivery and treatment
Zhenping Cao, Xinyue Wang, Yan Pang, Shanshan Cheng, Jinyao Liu
Nature Communications.2019;[Epub] CrossRef - Phloretin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by regulating the gut microbiota
Minna Wu, Puze Li, Yunying An, Jie Ren, Dong Yan, Jiazeng Cui, Duan Li, Min Li, Mingyong Wang, Genshen Zhong
Pharmacological Research.2019; 150: 104489. CrossRef - Commensal and Pathogenic Bacteria Indirectly Induce IL-22 but Not IFNγ Production From Human Colonic ILC3s via Multiple Mechanisms
Moriah J. Castleman, Stephanie M. Dillon, Christine M. Purba, Andrew C. Cogswell, Jon J. Kibbie, Martin D. McCarter, Mario L. Santiago, Edward Barker, Cara C. Wilson
Frontiers in Immunology.2019;[Epub] CrossRef - Ursodeoxycholic acid: a promising therapeutic target for inflammatory bowel diseases?
Stephen J. Keely, Clifford J. Steer, Natalia K. Lajczak-McGinley
American Journal of Physiology-Gastrointestinal and Liver Physiology.2019; 317(6): G872. CrossRef - Probiotics: If It Does Not Help It Does Not Do Any Harm. Really?
Aaron Lerner, Yehuda Shoenfeld, Torsten Matthias
Microorganisms.2019; 7(4): 104. CrossRef - Linking the gut and liver: crosstalk between regulatory T cells and mucosa-associated invariant T cells
Muhammad Atif, Suz Warner, Ye H. Oo
Hepatology International.2018; 12(4): 305. CrossRef - Gut microbiomes and their metabolites shape human and animal health
Woojun Park
Journal of Microbiology.2018; 56(3): 151. CrossRef - Multispecies Probiotic Supplementation Favorably Affects Vascular Function and Reduces Arterial Stiffness in Obese Postmenopausal Women—A 12-Week Placebo-Controlled and Randomized Clinical Study
Monika Szulińska, Igor Łoniewski, Katarzyna Skrypnik, Magdalena Sobieska, Katarzyna Korybalska, Joanna Suliburska, Paweł Bogdański
Nutrients.2018; 10(11): 1672. CrossRef - Update on the Gastrointestinal Microbiome in Systemic Sclerosis
Chiara Bellocchi, Elizabeth R. Volkmann
Current Rheumatology Reports.2018;[Epub] CrossRef - Impact of Retinoic Acid on Immune Cells and Inflammatory Diseases
Luana de Mendonça Oliveira, Franciane Mouradian Emidio Teixeira, Maria Notomi Sato
Mediators of Inflammation.2018; 2018: 1. CrossRef - Micronized Cells of the Probiotic Strain Bifidobacterium lactis BS01 Activate Monocyte Polarization
Luca Mogna, Angela Amoruso, Marco Pane, Stefania Nicola, Serena Allesina, Francesca Deidda
Journal of Clinical Gastroenterology.2018; 52(Supplement): S57. CrossRef
|
MSK
PDF
Supplementary Material
