- Effects of Mutations in the WD40 Domain of α-COP on Its Interaction with the COPI Coatomer in Saccharomyces cerevisiae
-
Ki-Hyun Kim , Eun Kyung Kim , Ki Young Jeong , Yun-Hee Park , Hee-Moon Park
-
J. Microbiol. 2012;50(2):256-262. Published online April 27, 2012
-
DOI: https://doi.org/10.1007/s12275-012-1326-z
-
-
793
View
-
0
Download
-
5
Crossref
-
 Abstract
 PDF
-
Replacement of glycine 227 in the fifth WD40 motif of
α-COP/Ret1p/Soo1p by charged or aromatic amino acids is
responsible for the temperature-dependent osmo-sensitivity
of Saccharomyces cerevisiae, while truncations of WD40
motifs exerted a reduction in cell growth rate and impairment
in assembly of cell-wall associated proteins such as
enolase and Gas1p. Yeast two-hybrid analysis revealed that
the ret1-1/soo1-1 mutation of α-COP abolished the interaction
with β- and ε-COP, respectively, and that the interaction
between α-COP and β-COP relied on the WD40 domain
of α-COP. Furthermore, although the WD40 domain
is dispensable for interaction of α-COP with ε-COP, structural
alterations in the WD40 domain could impair the
interaction.
-
Citations
Citations to this article as recorded by  - Dissecting the essential role of N-glycosylation in catalytic performance of xanthan lyase
Jingjing Zhao, Qian Wang, Xin Ni, Shaonian Shen, Chenchen Nan, Xianzhen Li, Xiaoyi Chen, Fan Yang
Bioresources and Bioprocessing.2022;[Epub] CrossRef - Transcriptional Regulation of Anthocyanin Synthesis by MYB-bHLH-WDR Complexes in Kiwifruit (Actinidia chinensis)
Yanfei Liu, Kangxun Ma, Yingwei Qi, Guowen Lv, Xiaolin Ren, Zhande Liu, Fengwang Ma
Journal of Agricultural and Food Chemistry.2021; 69(12): 3677. CrossRef - Identification and expression profile of an alpha-COPI homologous gene (COPA1) involved in high irradiance and salinity stress in Haematococcus pluvialis
Qiulan Luo, Jingjing Ning, Zhangli Hu, Chaogang Wang
Algal Research.2017; 28: 220. CrossRef - Depletion of ε-COP in the COPI Vesicular Coat Reduces Cleistothecium Production inAspergillus nidulans
Eun-Hye Kang, Eun-Jung Song, Jun Ho Kook, Hwan-Hee Lee, Bo-Ri Jeong, Hee-Moon Park
Mycobiology.2015; 43(1): 31. CrossRef - Analysis of Protein Domain for Interaction between α-COP and ε-COP in Aspergillus nidulans
Eun-Jung Song, Ki-Hyun Kim, Hwan-Hee Lee, Jeong-Seok Park, Eun-Hye Kang, Hee-Moon Park
The Korean Journal of Mycology.2012; 40(4): 224. CrossRef
|
MSK
