Journal of Microbiology

Jae-Gu Han

3 Articles

Species identity of Phellinus linteus (sanghuang) extensively used as a medicinal mushroom in Korea: Jae-Gu Han , Min-Woo Hyun , Chang Sun Kim , Jong Won Jo , Jae-Han Cho , Kang-Hyo Lee , Won-Sik Kong , Sang-Kuk Han , Junsang Oh , Gi-Ho Sung; J. Microbiol. 2016;54(4):290-295. Published online April 1, 2016; DOI: https://doi.org/10.1007/s12275-016-5520-2

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Sanghuang is a medicinal mushroom that has gained particular attention in Korea. It has been extensively studied for the past few decades as a natural immune booster and cancer suppressor. Although the scientific name, Phellinus linteus, has been commonly used to refer to the sanghuang mushroom, the species identity of sanghuang has been called into question due to the ambiguity of its circumscription and the inadequacy of morphological distinctions within allied species. Because the species concept of sanghuang has been elucidated by recent molecular phylogenetic studies, it has become necessary to clarify the taxonomic positions of sanghuang strains extensively utilized in Korea. We conducted a phylogenetic analysis of 74 strains belonging to the P. linteus-baumii complex based on ITS nrDNA sequences. Parental stains of sanghuang varieties formally registered in the Korea Seed & Variety Service, including ASI 26046 (Corea sanghuang), 26114 (Boolro), and 26115 (HK 1-ho) were grouped with Sanghuangporus sanghuang instead of P. linteus in the inferred phylogeny.

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A conserved terpene cyclase gene in Sanghuangporus for abscisic acid-related sesquiterpenoid biosynthesis
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BMC Genomics.2025;[Epub] CrossRef
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The first complete mitochondrial genome of Phellinus pomaceus var. prunastri (Pers.) Pat. 1926 (Hymenochaetales: Hymenochaetaceae) and phylogenetic analysis
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Preparation, characterization and cytotoxic activity of selenium nanoparticles stabilized with a heteropolysaccharide isolated from Sanghuangporus vaninii residue
Wenqi Chu, Peng Liu, Zhong Zhang, Di Wu, Wen Li, Wanchao Chen, Zhengpeng Li, Weike Wang, Yan Yang
Carbohydrate Polymers.2024; 343: 122468. CrossRef
Comparative genomic analysis of Sanghuangporus sanghuang with other Hymenochaetaceae species
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Frontiers in Pharmacology.2023;[Epub] CrossRef
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Pilot Study: Nutritional and Preclinical Safety Investigation of Fermented Hispidin-Enriched Sanghuangporus sanghuang Mycelia: A Promising Functional Food Material to Improve Sleep
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A rapid analysis of antioxidants in Sanghuangporus baumii by online extraction-HPLC-ABTS
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IMA Fungus.2021;[Epub] CrossRef
Anti-inflammatory effect of hispidin on LPS induced macrophage inflammation through MAPK and JAK1/STAT3 signaling pathways
Ying-Hao Han, Dong-Qin Chen, Mei-Hua Jin, Ying-Hua Jin, Jing Li, Gui-Nan Shen, Wei-Long Li, Yi-Xi Gong, Ying-Ying Mao, Dan-Ping Xie, Dong-Seok Lee, Li-Yun Yu, Sun-Uk Kim, Ji-Su Kim, Taeho Kwon, Yu-Dong Cui, Hu-Nan Sun
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Phellinus baumii enhances the immune response in cyclophosphamide-induced immunosuppressed mice
Jeong-Hyun Yoo, You-Suk Lee, SaeKwang Ku, Hae-Jeung Lee
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Optimized production and safety evaluation of hispidin‐enriched Sanghuangporus sanghuang mycelia
I‐Chen Li, Chang Cheng Chen, Sen‐Je Sheu, I‐Hsuan Huang, Chin‐Chu Chen
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Cyclofarnesane sesquiterpenoids from the fungus Sanghuangporus sp.
Oue-artorn Rajachan, Aphidech Sangdee, Kwanjai Kanokmedhakul, Sarawut Tontapha, Vittaya Amornkitbamrung, Somdej Kanokmedhakul
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Species Diversity, Phylogeny, Divergence Time, and Biogeography of the Genus Sanghuangporus (Basidiomycota)
Lin Zhu, Jie Song, Jun-Liang Zhou, Jing Si, Bao-Kai Cui
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Protective effect of a polyphenols-rich extract from Inonotus Sanghuang on bleomycin-induced acute lung injury in mice
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Evaluation of antioxidant, anti-inflammatory and anti-proliferative activities of ethanol extracts from different varieties of Sanghuang species
Wang-Ching Lin, Jeng-Shyan Deng, Shyh-Shyun Huang, Sheng-Hua Wu, Hui-Yi Lin, Guan-Jhong Huang
RSC Advances.2017; 7(13): 7780. CrossRef

Studies on seasonal dynamics of soil-higher fungal communities in Mongolian oak-dominant Gwangneung forest in Korea: Chang Sun Kim , Jong Woo Nam , Jong Won Jo , Sang-Yong Kim , Jae-Gu Han , Min Woo Hyun , Gi-Ho Sung , Sang-Kuk Han; J. Microbiol. 2016;54(1):14-22. Published online January 5, 2016; DOI: https://doi.org/10.1007/s12275-016-5521-1

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Abstract PDF

We surveyed macrofungi biweekly at defined plots from April to December in 2014, in the Mongolian oak-dominant forest, Gwangneung Forest, Pochen-si, Korea, and analyzed a soilhigher fungal diversity during four seasons (represented by April, August, October, and December). Based on morphological observation of collected specimens, the collected macrofungi were classified into 2 phyla 3 classes 7 orders, 14 families, 21 genera, and 33 species (36 specimens). DNA-based community analyses indicated that soil-higher fungi were classified into 2 phyla, 18 classes, 49 orders, 101 families, and 155 genera (83,360 sequence reads), defined herein as 155 genus-level operational taxonomic units (GOTUs). In the present study, we evaluated and discussed the fungal diversity in seasonal dynamics and soil layers based on collected macrofungi and pyrosequencing data while considering environmental parameters (pH, exchangeable K, T-P, NH4+, NO3-, OM, WR, TOC, and T-N). Moreover, principal components analysis (PCA) showed distinct clusters of the GOTU assemblage associated with the seasons.

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Fire-Induced Changes in Soil Properties and Bacterial Communities in Rotational Shifting Cultivation Fields in Northern Thailand
Noppol Arunrat, Chakriya Sansupa, Sukanya Sereenonchai, Ryusuke Hatano, Rattan Lal
Biology.2024; 13(6): 383. CrossRef
Diversity and species distribution of lichens in Gwangneung Forest
Jung Shin Park, En-Mi Sun, Jung-Jae Woo, Sang-Kuk Han, Soon-Ok Oh
Journal of Asia-Pacific Biodiversity.2022; 15(4): 613. CrossRef
Statistical Evidence for Managing Forest Density in Consideration of Natural Volatile Organic Compounds
Yeji Choi, Geonwoo Kim, Sujin Park, Sangtae Lee, Soojin Kim, Eunsoo Kim
Atmosphere.2021; 12(9): 1113. CrossRef
Immediate and legacy effects of snow exclusion on soil fungal diversity and community composition
Li Zhang, Yuzhi Ren, Kaijun Yang, Zhijie Li, Bo Tan, Yang Liu, Han Li, Chengming You, Sining Liu, Lixia Wang, Rui Yin, Jian Zhang, Zhenfeng Xu
Forest Ecosystems.2021;[Epub] CrossRef
Comparison of Soil Higher Fungal Communities between Dead and Living Abies koreana in Mt. Halla, the Republic of Korea
Chang Sun Kim, Jong Won Jo, Hyen Lee, Young-Nam Kwag, Sung Eun Cho, Seung Hwan Oh
Mycobiology.2020; 48(5): 364. CrossRef
Macrofungal diversity of urbanized areas in southern part of Korea
Sung Eun Cho, Young-Nam Kwag, Jong Won Jo, Sang-Kuk Han, Seung Hwan Oh, Chang Sun Kim
Journal of Asia-Pacific Biodiversity.2020; 13(2): 189. CrossRef
Seasonal Change in Microbial Diversity and Its Relationship with Soil Chemical Properties in an Orchard
Xuhui Luo, Ming Kuang Wang, Guiping Hu, Boqi Weng, Varenyam Achal
PLOS ONE.2019; 14(12): e0215556. CrossRef
One-time nitrogen fertilization shifts switchgrass soil microbiomes within a context of larger spatial and temporal variation
Huaihai Chen, Zamin K. Yang, Dan Yip, Reese H. Morris, Steven J. Lebreux, Melissa A. Cregger, Dawn M. Klingeman, Dafeng Hui, Robert L. Hettich, Steven W. Wilhelm, Gangsheng Wang, Frank E. Löffler, Christopher W. Schadt, Gabriel Moreno-Hagelsieb
PLOS ONE.2019; 14(6): e0211310. CrossRef
Guild Patterns of Basidiomycetes Community Associated With Quercus mongolica in Mt. Jeombong, Republic of Korea
Seung-Yoon Oh, Hae Jin Cho, John A. Eimes, Sang-Kuk Han, Chang Sun Kim, Young Woon Lim
Mycobiology.2018; 46(1): 13. CrossRef
Fungal communities in a Korean red pine stand, Gwangneung Forest, Korea
Chang Sun Kim, Sang-Kuk Han, Jong Woo Nam, Jong Won Jo, Young-Nam Kwag, Jae-Gu Han, Gi-Ho Sung, Young Woon Lim, Seunghwan Oh
Journal of Asia-Pacific Biodiversity.2017; 10(4): 559. CrossRef

Mitochondrial Phylogeny Reveals Intraspecific Variation in Peronospora effusa, the Spinach Downy Mildew Pathogen: Young-Joon Choi , Marco Thines , Jae-Gu Han , Hyeon-Dong Shin; J. Microbiol. 2011;49(6):1039-1043. Published online December 28, 2011; DOI: https://doi.org/10.1007/s12275-011-1069-2

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Since about two hundred years, downy mildew caused by Peronospora effusa is probably the most economically important disease of spinach (Spinacia oleracea). However, there is no information on the global phylogeographic structure of the pathogen and thus it is unclear whether a single genotype occurs worldwide
or whether some local genetic variation exists. To investigate the genetic variability of this pathogen, a sequence analysis of two partial mitochondrial DNA genes, cox2 and nad1, was carried out. Thirty-three specimens of Peronospora effusa from four continents were analyzed, including samples from Australia, China, Japan, Korea, Mexico, Russia, Sweden, and the USA. Despite the potential anthropogenic admixture of genotypes, a phylogeographic pattern was observed, which corresponds to two major groups, an Asian/Oceanian clade and another group, which includes American/European specimens. Notably, two of six Japanese specimens investigated did not belong to the Asian/Oceanian clade, but were identical to three of the specimens from the USA, suggestive of a recent introduction from the USA to Japan. As similar introduction events may be occurring as a result of the globalised trade with plant and seed material, a better knowledge of the phylogeographic distribution of pathogens is highly warranted for food security purposes.

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