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Hoon Park 1 Article
Genome-Wide Transcriptional Responses to Sulfite in Saccharomyces cerevisiae
Hoon Park , Yoon-Sun Hwan
J. Microbiol. 2008;46(5):542-548.   Published online October 31, 2008
DOI: https://doi.org/10.1007/s12275-008-0053-y
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AbstractAbstract PDF
Sulfite is a commonly used preservative in foods, beverages, and pharmaceuticals because it is toxic to many microorganisms. In order to understand the global response of Saccharomyces cerevisiae to sulfite, genome-wide transcript profiling following sulfite exposure was obtained. The transcription levels of 21 genes were increased more than 2-fold, while those of 37 genes decreased to a similar extent. Genes involved in carbohydrate metabolism represented the highest proportion of induced genes, which may account for the easily acquired resistance to sulfite. Most of down-regulated genes are involved in transcription, protein biosynthesis, and cell growth. The down-regulation of these genes is thought to reflect growth arrest which occurs during sulfite treatment, allowing cells to save energy. Cells treated with sulfite generated more than 70% of acetaldehyde than untreated cells, suggesting that the increased acetaldehyde production is correlated with the induction of PDC1 gene encoding pyruvate decarboxylase.

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    Frontiers in Microbiology.2020;[Epub]     CrossRef
  • Response to Sulfur Dioxide Addition by Two Commercial Saccharomyces cerevisiae Strains
    Sydney C. Morgan, Jade J. Haggerty, Britney Johnston, Vladimir Jiranek, Daniel M. Durall
    Fermentation.2019; 5(3): 69.     CrossRef
  • Brettanomyces bruxellensis SSU1Haplotypes Confer Different Levels of Sulfite Tolerance When Expressed in aSaccharomyces cerevisiae SSU1Null Mutant
    C. Varela, C. Bartel, M. Roach, A. Borneman, C. Curtin, M. Julia Pettinari
    Applied and Environmental Microbiology.2019;[Epub]     CrossRef
  • Adaptation of Candida albicans to Reactive Sulfur Species
    Yasmin Chebaro, Michael Lorenz, Alice Fa, Rui Zheng, Michael Gustin
    Genetics.2017; 206(1): 151.     CrossRef
  • Different mechanisms of resistance modulate sulfite tolerance in wine yeasts
    Chiara Nadai, Laura Treu, Stefano Campanaro, Alessio Giacomini, Viviana Corich
    Applied Microbiology and Biotechnology.2016; 100(2): 797.     CrossRef
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    D.B.R.K. Gupta Udatha, Evangelos Topakas, Margarita Salazar, Lisbeth Olsson, Mikael R. Andersen, Gianni Panagiotou
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    PLoS ONE.2014; 9(1): e86298.     CrossRef
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  • Functional annotations for the Saccharomyces cerevisiae genome: the knowns and the known unknowns
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