- Erratum: Secretions from Serratia marcescens Inhibit the Growth and Biofilm Formation of Candida spp. and Cryptococcus neoformans
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Caiyan Xin , Fen Wang , Jinping Zhang , Quan Zhou , Fangyan Liu , Chunling Zhao , Zhangyong Song
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J. Microbiol. 2023;61(4):479-479.
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DOI: https://doi.org/10.1007/s12275-023-00037-5
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Erratum: Journal of Microbiology (2023) 61:221–232
https://doi.org/10.1007/s12275-022-00007-3
In this article the acknowledgment has been given erroneously.
It should be read as follows:
This research was supported financially by the Sichuan
Science and Technology Program (2023NSFSC1698,
2023NSFSC0529, 2022NSFSC1539, and 2022YFS0629)
and Luzhou (2021-JYJ-73 and 2022-JYJ-159), the Technology
Strategic Cooperation Project of Luzhou Municipal
People’s Government Southwest Medical University
(2020LZXNYDJ38 and 2020LZXNYDJ23), and the Foundation
of Southwest Medical University (2021ZKMS008,
2022QN042, 2022QN085, 2022QN102, and 2022QN118).
The original article has been corrected.
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Citations
Citations to this article as recorded by 
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Sensitive bioluminescence imaging of cryptococcosis in
Galleria mellonella
improves antifungal screening under
in vivo
conditions
Eliane Vanhoffelen, Lori Vermoesen, Lauren Michiels, Katrien Lagrou, Agustin Reséndiz-Sharpe, Greetje Vande Velde Virulence.2024;[Epub] CrossRef
- Secretions from Serratia marcescens Inhibit the Growth and Biofilm Formation of Candida spp. and Cryptococcus neoformans
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Caiyan Xin , Fen Wang , Jinping Zhang , Quan Zhou , Fangyan Liu , Chunling Zhao , Zhangyong Song
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J. Microbiol. 2023;61(2):221-232. Published online February 21, 2023
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DOI: https://doi.org/10.1007/s12275-022-00007-3
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1,035
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Abstract
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Candida spp. and Cryptococcus are conditional pathogenic fungi that commonly infect immunocompromised patients.
Over the past few decades, the increase in antifungal resistance has prompted the development of new antifungal agents. In
this study, we explored the potential antifungal effects of secretions from Serratia marcescens on Candida spp. and Cryptococcus
neoformans. We confirmed that the supernatant of S. marcescens inhibited fungal growth, suppressed hyphal and
biofilm formation, and downregulated the expression of hyphae-specific genes and virulence-related genes in Candida spp.
and C. neoformans. Furthermore, the S. marcescens supernatant retained biological stability after heat, pH, and protease
K treatment. The chemical profile of the S. marcescens supernatant was characterized by ultra-high-performance liquid
chromatography–linear ion trap/orbitrap high resolution mass spectrometry analysis and a total of 61 compounds with an
mzCloud best match of greater than 70 were identified. In vivo, treatment with the S. marcescens supernatant reduced the
mortality of fungi-infected Galleria mellonella. Taken together, our results revealed that the stable antifungal substances in
the supernatant of S. marcescens have promising potential applications in the development of new antifungal agents.
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Citations
Citations to this article as recorded by 
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