- Differences in seroprevalence between epicenter and non-epicenter areas of the COVID-19 outbreak in South Korea
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Hye Won Jeong , Hyun-Ha Chang , Eun Ji Kim , Yu Kyung Kim , Se-Mi Kim , Eun-Ha Kim , Young-Il Kim , Mark Anthony B. Casel , Seong-Gyu Kim , Rare Rollon , Seung-Gyu Jang , Kwang-Min Yu , Hee-Sung Kim , Hee Sue Park , Su-Jin Park , Yong-Dae Kim , Eung-Gook Kim , Young Ki Choi
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J. Microbiol. 2021;59(5):530-533. Published online April 28, 2021
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DOI: https://doi.org/10.1007/s12275-021-1095-7
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 Abstract
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To compare the standardized severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) seroprevalence of high
epicenter region with non-epicenter region, serological studies
were performed with a total of 3,268 sera from Daegu City
and 3,981 sera from Chungbuk Province. Indirect immunofluorescence
assay (IFA) for SARS-CoV-2 IgG results showed
a high seroprevalence rate in the Daegu City (epicenter) compared
with a non-epicenter area (Chungbuk Province) (1.27%
vs. 0.91%, P = 0.0358). It is noteworthy that the highest seroprevalence
in Daegu City was found in elderly patients (70’s)
whereas young adult patients (20’s) in Chungbuk Province
showed the highest seroprevalence. Neutralizing antibody
(NAb) titers were found in three samples from Daegu City
(3/3, 268, 0.09%) while none of the samples from Chungbuk
Province were NAb positive. These results demonstrated that
even following the large outbreak, the seropositive rate of
SARS-CoV-2 in the general population remained low in
South Korea.
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Citations
Citations to this article as recorded by  - Integrated Clinical and Social Impacts of the COVID-19 Pandemic in Korea: A Combined Systematic and Narrative Review
Yumi Jang, Jaehun Jung, Kyong Ran Peck
Journal of Korean Medical Science.2026;[Epub] CrossRef - Distinctive Combinations of RBD Mutations Contribute to Antibody Evasion in the Case of the SARS-CoV-2 Beta Variant
Tae-Hun Kim, Sojung Bae, Sunggeun Goo, Jinjong Myoung
Journal of Microbiology and Biotechnology.2023; 33(12): 1587. CrossRef - The Seroprevalence of SARS-CoV-2 in Children During Early COVID-19 Pandemic in Korea: A Nationwide, Population-Based Study
Jin Lee, Young June Choe, Dohsik Minn, Jong-Hyun Kim
Journal of Korean Medical Science.2022;[Epub] CrossRef
- Differentiation of Acremonium chrysogenum M35 in Submerged Culture with Glass Beads or Silicone Rubbers
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Hwan Hyo Lee , Hyun Yong Shin , Eun Ji Kim , Seung Wook Kim
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J. Microbiol. 2010;48(6):734-738. Published online January 9, 2011
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DOI: https://doi.org/10.1007/s12275-010-0108-8
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766
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4
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Abstract
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In this study, we investigated the effects of glass beads and silicone rubbers on the differentiation and morphological changes of A. chrysogenum M35 in submerged culture. Differentiation in the center of the cell pellets was improved by the addition of glass beads or silicone rubbers to the primary medium. The fragmentation rate constant (kfrag), which is used to estimate the tensile strength of fungal hyphae, was increased by more than 40% in baffled flasks containing glass beads. The maximum fragmentation rate was also increased by 48% when silicone rubbers were added to a 5 L bioreactor containing the culture. During the cultivation in the main medium with 6 glass beads, the value of the fractal dimension increased by about
8% when it was compared with baffled flasks without glass beads. Additionally, the number of arthrospores and the dry cell weight were increased by more than 10% in baffled flasks containing beads. The degree of roundness, which is the ratio of the object area to the longest Feret diameter, was decreased from 0.85 at day 1 to 0.77 at day 5. The differentiation of A. chrysogenum M35 was also supposedly closely related with the enlargement of the cell surfaces. Taken together, these results indicate that complex changes in morphology resulted in increased cell growth and differentiation in the culture broth containing glass beads and silicone rubbers.
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Citations
Citations to this article as recorded by - Valorization of corncobs into cephalosporin C through predictive modeling of the dilute acid hydrolysis and detoxification process
Seunghee Kim, Jeongho Lee, Hyerim Son, Yunseok Song, Soeun Shin, Minji Kim, Kang Hyun Lee, Chulhwan Park, Hah Young Yoo
Environmental Technology & Innovation.2026; 43: 105161. CrossRef - Concept for sustainable biorefinery process utilizing corn cobs as feedstock: Conversion to cephalosporin C via dilute acid hydrolysis and detoxification
Chan Kyum Kim, Seunghee Kim, Jeongho Lee, Kang Hyun Lee, Hah Young Yoo, Chun-Woong Park
Journal of Industrial and Engineering Chemistry.2025; 150: 449. CrossRef - FRACTAL ANALYSIS OF LIPASE–CATALYSED SYNTHESIS OF BUTYL BUTYRATE IN A MICROBIOREACTOR UNDER THE INFLUENCE OF NOISE
PRATAP R. PATNAIK
Fractals.2013; 21(01): 1350007. CrossRef - Production of cephalosporin C using crude glycerol in fed-batch culture of Acremonium chrysogenum M35
Hyun Yong Shin, Jin Young Lee, Han Suk Choi, Ja Hyun Lee, Seung Wook Kim
The Journal of Microbiology.2011; 49(5): 753. CrossRef
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