- Dimethyl sulfoxide reduction by a hyperhermophilic archaeon Thermococcus onnurineus NA1 via a cysteine-cystine redox shuttle
-
Ae Ran Choi , Min-Sik Kim , Sung Gyun Kang , Hyun Sook Lee
-
J. Microbiol. 2016;54(1):31-38. Published online January 5, 2016
-
DOI: https://doi.org/10.1007/s12275-016-5574-1
-
-
918
View
-
0
Download
-
9
Crossref
-
 Abstract
 PDF
-
A variety of microbes grow by respiration with dimethyl sulfoxide
(DMSO) as an electron acceptor, and several distinct
DMSO respiratory systems, consisting of electron carriers
and a terminal DMSO reductase, have been characterized.
The heterotrophic growth of a hyperthermophilic archaeon
Thermococcus onnurineus NA1 was enhanced by the addition
of DMSO, but the archaeon was not capable of reducing
DMSO to DMS directly using a DMSO reductase. Instead, the
archaeon reduced DMSO via a cysteine-cystine redox shuttle
through a mechanism whereby cystine is microbially reduced
to cysteine, which is then reoxidized by DMSO reduction.
A thioredoxin reductase-protein disulfide oxidoreductase
redox couple was identified to have intracellular cystine-reducing
activity, permitting recycle of cysteine. This study presents
the first example of DMSO reduction via an electron
shuttle. Several Thermococcales species also exhibited enhanced
growth coupled with DMSO reduction, probably by
disposing of excess reducing power rather than conserving
energy.
-
Citations
Citations to this article as recorded by  - H2-dependent reduction of rubredoxin by FrhAGB hydrogenase in Thermococcus onnurineus NA1
Ji-in Yang, Hye-Jin Park, Young Jun An, Bo Gyoung Choi, Myeong-Eun Jegal, Hyun-Myung Oh, Sung Gyun Kang, Hyun Sook Lee
Applied Microbiology and Biotechnology.2026;[Epub] CrossRef - Outstanding lithium storage performance of a copper coordination complex [Cu(DMSO)2]Cl2 as anode material for lithium-ion batteries
Youkui Wang, Ruili Zhao, Jiamiao Ma, Jiamin Zhao, Yanmeng Cai, Qing Yuan, Jinsheng Zhao
Journal of Energy Storage.2025; 116: 116045. CrossRef - Heavy Metal-Resistant Biohybrid System Boosts Dissimilatory Nitrate Reduction to Ammonium for Agronomic Sustainability
Jialin Chi, Shiyin Wu, Liping Fang, Kai Liu, Shaochen Huang, Wenjun Zhang, Fangbai Li
ACS Sustainable Chemistry & Engineering.2024; 12(44): 16444. CrossRef - Phenotypic and genomic characterization of Bathyarchaeum tardum gen. nov., sp. nov., a cultivated representative of the archaeal class Bathyarchaeia
Maria A. Khomyakova, Alexander Y. Merkel, Dana D. Mamiy, Alexandra A. Klyukina, Alexander I. Slobodkin
Frontiers in Microbiology.2023;[Epub] CrossRef -
Direct Electron Transfer between the
frhAGB
-Encoded Hydrogenase and Thioredoxin Reductase in the Nonmethanogenic Archaeon
Thermococcus onnurineus
NA1
Hae-Chang Jung, Jae Kyu Lim, Tae-Jun Yang, Sung Gyun Kang, Hyun Sook Lee, Haruyuki Atomi
Applied and Environmental Microbiology.2020;[Epub] CrossRef - A peroxiredoxin of Thermus thermophilus HB27: Biochemical characterization of a new player in the antioxidant defence
Gabriella Fiorentino, Patrizia Contursi, Giovanni Gallo, Simonetta Bartolucci, Danila Limauro
International Journal of Biological Macromolecules.2020; 153: 608. CrossRef - A Reexamination of Thioredoxin Reductase from Thermoplasma acidophilum, a Thermoacidophilic Euryarchaeon, Identifies It as an NADH-Dependent
Enzyme
Dwi Susanti, Usha Loganathan, Austin Compton, Biswarup Mukhopadhyay
ACS Omega.2017; 2(8): 4180. CrossRef - Redox regulation of SurR by protein disulfide oxidoreductase in Thermococcus onnurineus NA1
Jae Kyu Lim, Hae-Chang Jung, Sung Gyun Kang, Hyun Sook Lee
Extremophiles.2017; 21(3): 491. CrossRef - Exploring membrane respiratory chains
Bruno C. Marreiros, Filipa Calisto, Paulo J. Castro, Afonso M. Duarte, Filipa V. Sena, Andreia F. Silva, Filipe M. Sousa, Miguel Teixeira, Patrícia N. Refojo, Manuela M. Pereira
Biochimica et Biophysica Acta (BBA) - Bioenergetics.2016; 1857(8): 1039. CrossRef
|
MSK
