- Volume 50(5); October 2012
-
Review
- REVIEW] The Role of Type III Secretion System 2 in Vibrio parahaemolyticus Pathogenicity
-
Hyeilin Ham , Kim Orth
-
J. Microbiol. 2012;50(5):719-725. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2550-2
-
-
169
View
-
0
Download
-
47
Crossref
-
Abstract
-
Vibrio parahaemolyticus, a Gram-negative marine bacterial pathogen, is emerging as a major cause of food-borne illnesses worldwide due to the consumption of raw seafood leading to diseases including gastroenteritis, wound infection, and septicemia. The bacteria utilize toxins and type III secretion system (T3SS) to trigger virulence. T3SS is a multi-subunit needle-like apparatus used to deliver bacterial proteins, termed effectors, into the host cytoplasm which then target various eukaryotic signaling pathways. V. parahaemolyticus carries two T3SSs in each of its two chromosomes, named T3SS1 and T3SS2, both of which play crucial yet distinct roles during infection: T3SS1 causes cytotoxicity whereas T3SS2 is mainly associated with enterotoxicity. Each T3SS secretes a unique set of effectors that contribute to virulence by acting on different host targets and serving different functions. Emerging studies on T3SS2 of V. parahaemolyticus, reveal its regulation, translocation, discovery, characterization of its effectors, and development of animal models to understand the enterotoxicity. This review on recent findings for T3SS2 of V. parahaemolyticus highlights a novel mechanism of invasion that appears to be conserved by other marine bacteria.
-
Citations
Citations to this article as recorded by

-
The CueR-regulated transporters CopA and CusFABC coordinate copper detoxification in
Vibrio parahaemolyticus
Chengkun Zheng, Yimeng Zhai, Mengxian Wang, Zhengzhong Xu, Yunzeng Zhang, Xiaohui Zhou, Xiang Chen, Xinan Jiao
Virulence.2025;[Epub] CrossRef - Untargeted ¹H NMR Metabolomics of Elephantopus Scaber Reveals Correlation with Anti-Vibrio Activity
Azizul Isha, Noraznita Sharifuddin, Mazni Abu Zarin, Yaya Rukayadi, Ahmad Faizal Abdull Razis
Journal of Pharmaceutical Innovation.2025;[Epub] CrossRef -
Role of the TPR family protein VPA1365 in regulating type III secretion system 2 and virulence in
Vibrio parahaemolyticus
Wenliang Yin, Mengyan Wan, Youkun Zhang, Hongmei Meng, Zhiming Pan, Xinan Jiao, Dan Gu, Edward G. Dudley
Applied and Environmental Microbiology.2025;[Epub] CrossRef - Engineering non-pathogenic bacteria for auto-transporter-driven secretion of functional interferon
May Tfilin Samuel, Irina Rostovsky, Alona Kuzmina, Ran Taube, Neta Sal-Man
Gut Microbes.2025;[Epub] CrossRef - Global phylogeography and genomic characterization of Vibrio parahaemolyticus infections in Jilin province, China (2016–2022)
Jingying Zheng, Ben Shi, Jingyu Sun, Yang Pan, Yukun Ding, Xuening Shi, Jing Zhang, Huiling Zhang, Jingtong He, Kunlun Zhang, Jianyang Shi, Yang Bai, Wei Zhao, Juan Wang
International Journal of Food Microbiology.2025; 428: 110993. CrossRef - Contribution of the Type III Secretion System (T3SS2) of Vibrio parahaemolyticus in Mitochondrial Stress in Human Intestinal Cells
Nicolás Plaza, Diliana Pérez-Reytor, Gino Corsini, Katherine García, Ítalo M. Urrutia
Microorganisms.2024; 12(4): 813. CrossRef - Correlation analysis of whole genome sequencing of a pathogenic Escherichia coli strain of Inner Mongolian origin
Yan Jia, Kai Zhang, Jinshan Cao, Wei Mao
Scientific Reports.2024;[Epub] CrossRef - Mitigation of T3SS-mediated virulence in waterborne pathogenic bacteria by multi-electrode cylindrical-DBD plasma-generated nitric oxide water
Shweta B. Borkar, Manorma Negi, Tirtha Raj Acharya, Prajwal Lamichhane, Neha Kaushik, Eun Ha Choi, Nagendra Kumar Kaushik
Chemosphere.2024; 350: 140997. CrossRef - Characterization and genomic analysis of a broad-spectrum lytic phage PG288: A potential natural therapy candidate for Vibrio infections
Chen Zhang, Xixi Li, Shen'ao Li, Han Yin, Zhe Zhao
Virus Research.2024; 341: 199320. CrossRef - Pathology and pathogenesis of Vibrio infection in fish: A review
Tilusha Manchanayake, Annas Salleh, Mohammad Noor Azmai Amal, Ina Salwany Md Yasin, Mohd Zamri-Saad
Aquaculture Reports.2023; 28: 101459. CrossRef - Genome Analysis Identifies a Novel Type III Secretion System (T3SS) Category in Vibrio Species
Douaa Zakaria, Shigeaki Matsuda, Tetsuya Iida, Tetsuya Hayashi, Masanori Arita
Microorganisms.2023; 11(2): 290. CrossRef - Transcriptomic analysis reveals the antibiofilm mechanism of Lacticaseibacillus rhamnosus MS1 against Vibrio parahaemolyticus
Xingguo Zhang, Wendan Shangguan, Jie Wang, Zhenlin Liao, Xiang Fang, Qingping Zhong
LWT.2023; 176: 114529. CrossRef - Comparative genomic analysis reveals the potential transmission of Vibrio parahaemolyticus from freshwater food to humans
Mingzhu Li, Haiyan Xu, Yuqi Tian, Youkun Zhang, Xinan Jiao, Dan Gu
Food Microbiology.2023; 113: 104277. CrossRef - Enzymatic Specificity of Conserved Rho GTPase Deamidases Promotes Invasion of Vibrio parahaemolyticus at the Expense of Infection
Alexander E. Lafrance, Suneeta Chimalapati, Nalleli Garcia Rodriguez, Lisa N. Kinch, Karan Gautam Kaval, Kim Orth, Edward G. Ruby
mBio.2022;[Epub] CrossRef - Prevention of Vibriosis using whole cell microalgae on tiger shrimp hatcheries
Nurbaya, Ince Ayu K. Kadriah, Muharijadi Atmomarsono, Muliani, Hilal Anshary
IOP Conference Series: Earth and Environmental Science.2022; 1119(1): 012041. CrossRef - Genomic stability among O3:K6 V. parahaemolyticus pandemic strains isolated between 1996 to 2012 in American countries
Abraham Guerrero, Bruno Gomez-Gil, Marcial Leonardo Lizarraga-Partida
BMC Genomic Data.2021;[Epub] CrossRef - De Novo Sequencing Provides Insights Into the Pathogenicity of Foodborne Vibrio parahaemolyticus
Jianfei Liu, Kewei Qin, Chenglin Wu, Kaifei Fu, Xiaojie Yu, Lijun Zhou
Frontiers in Cellular and Infection Microbiology.2021;[Epub] CrossRef - Secretion Systems in Gram-Negative Bacterial Fish Pathogens
Sophanit Mekasha, Dirk Linke
Frontiers in Microbiology.2021;[Epub] CrossRef - Genotypic Diversity and Pathogenic Potential of Clinical and Environmental Vibrio parahaemolyticus Isolates From Brazil
Leandro de O. Santos, Cristóvão A. de Lanna, Anna Carolina da C. Arcanjo, Paulo M. Bisch, Wanda M. A. von Krüger
Frontiers in Microbiology.2021;[Epub] CrossRef - T3SEpp: an Integrated Prediction Pipeline for Bacterial Type III Secreted Effectors
Xinjie Hui, Zewei Chen, Mingxiong Lin, Junya Zhang, Yueming Hu, Yingying Zeng, Xi Cheng, Le Ou-Yang, Ming-an Sun, Aaron P. White, Yejun Wang, Lee Ann McCue
mSystems.2020;[Epub] CrossRef - Prevalence, Antibiotic-Resistance, and Virulence Characteristics of Vibrio parahaemolyticus in Restaurant Fish Tanks in Seoul, South Korea
Hyo-Won Jeong, Jin-ah Kim, Su-Jin Jeon, Seong-Seon Choi, Min-Kyeong Kim, Hye-Jin Yi, Seok-Ju Cho, Il-Young Kim, Jung-Whan Chon, Dong-Hyeon Kim, Dongryeoul Bae, Hyunsook Kim, Kun-Ho Seo
Foodborne Pathogens and Disease.2020; 17(3): 209. CrossRef - Comprehensive genome based analysis of Vibrio parahaemolyticus for identifying novel drug and vaccine molecules: Subtractive proteomics and vaccinomics approach
Mahmudul Hasan, Kazi Faizul Azim, Md. Abdus Shukur Imran, Ishtiak Malique Chowdhury, Shah Rucksana Akhter Urme, Md. Sorwer Alam Parvez, Md. Bashir Uddin, Syed Sayeem Uddin Ahmed, Mohammed Abdelfatah Mosa Alhoot
PLOS ONE.2020; 15(8): e0237181. CrossRef - Development and Evaluation of Polymorphic Locus Sequence Typing for Epidemiological Tracking of Vibrio parahaemolyticus
Tom Edlind, Gary P. Richards
Foodborne Pathogens and Disease.2019; 16(11): 752. CrossRef - Genetic diversity, virulence factors and farm-to-table spread pattern of Vibrio parahaemolyticus food-associated isolates
Chao Yang, Xianglilan Zhang, Hang Fan, Yinghui Li, Qinghua Hu, Ruifu Yang, Yujun Cui
Food Microbiology.2019; 84: 103270. CrossRef - Piper betel Compounds Piperidine, Eugenyl Acetate, and Chlorogenic Acid Are Broad-Spectrum Anti-Vibrio Compounds that Are Also Effective on MDR Strains of the Pathogen
Erika Acosta-Smith, Nidia Leon-Sicairos, Sandeep Tiwari, Hector Flores-Villaseñor, Adrian Canizalez-Roman, Ranjith Kumavath, Preetam Ghosh, Vasco Azevedo, Debmalya Barh
Pathogens.2019; 8(2): 64. CrossRef - Inhibition of V.parahaemolyticus infection using the commensal E.coli HS in a tissue culture infection model
Fitua Al-Saedi, Suhad Faisal Hatem Al-Mugdadi, Mayssaa E Abdalah
Journal of Physics: Conference Series.2019; 1294: 062051. CrossRef - The Fate of Bacteria in Human Digestive Fluids: A New Perspective Into the Pathogenesis of Vibrio parahaemolyticus
Siqi Wang, Zhaohuan Zhang, Pradeep K. Malakar, Yingjie Pan, Yong Zhao
Frontiers in Microbiology.2019;[Epub] CrossRef - The extracellular proteases produced by Vibrio parahaemolyticus
George Osei-Adjei, Xinxiang Huang, Yiquan Zhang
World Journal of Microbiology and Biotechnology.2018;[Epub] CrossRef - Regulation of Thermostable Direct Hemolysin and Biofilm Formation of Vibrio parahaemolyticus by Quorum-Sensing Genes luxM and luxS
Muhan Guo, Zhijia Fang, Lijun Sun, Dongfang Sun, Yaling Wang, Can Li, Rundong Wang, Yang Liu, Hanqiao Hu, Ying Liu, Defeng Xu, Ravi Gooneratne
Current Microbiology.2018; 75(9): 1190. CrossRef - The mechanisms that regulate Vibrio parahaemolyticus virulence gene expression differ between pathotypes
Nicholas Petronella, Jennifer Ronholm
Microbial Genomics
.2018;[Epub] CrossRef - Vibrio Parahaemolyticus: A Review on Distribution, Pathogenesis, Virulence Determinants and Epidemiology
Lubna Ghenem, Nasreldin Elhadi, Faisal Alzahrani, Mitsuaki Nishibuchi
Saudi Journal of Medicine & Medical Sciences.2017; 5(2): 93. CrossRef - Genotyping and distribution of virulence factors in V. parahaemolyticus from seafood and environmental sources, South-west coast of India
Reshma Silvester, Ajin Madhavan, Ally Antony, Deborah Alexander, Sudha Santha, Bini Francis, Mohamed Hatha
Regional Studies in Marine Science.2017; 12: 64. CrossRef - Bioluminescence Imaging to Track Bacteroides fragilis Inhibition of Vibrio parahaemolyticus Infection in Mice
Zhengchao Li, Huimin Deng, Yazhou Zhou, Yafang Tan, Xiaoyi Wang, Yanping Han, Yangyang Liu, Ye Wang, Ruifu Yang, Yujing Bi, Fachao Zhi
Frontiers in Cellular and Infection Microbiology.2017;[Epub] CrossRef - Quorum Sensing Regulators Are Required for Metabolic Fitness in Vibrio parahaemolyticus
Sai Siddarth Kalburge, Megan R. Carpenter, Sharon Rozovsky, E. Fidelma Boyd, Shelley M. Payne
Infection and Immunity.2017;[Epub] CrossRef - Genomic Features of Environmental and Clinical Vibrio parahaemolyticus Isolates Lacking Recognized Virulence Factors Are Dissimilar
J. Ronholm, N. Petronella, C. Chew Leung, A. W. Pightling, S. K. Banerjee, H. L. Drake
Applied and Environmental Microbiology.2016; 82(4): 1102. CrossRef - Complete genome of Vibrio parahaemolyticus FORC014 isolated from the toothfish
Sojin Ahn, Han Young Chung, Sooyeon Lim, Kwondo Kim, Suyeon Kim, Eun Jung Na, Kelsey Caetano-Anolles, Ju-Hoon Lee, Sangryeol Ryu, Sang Ho Choi, Heebal Kim
Gut Pathogens.2016;[Epub] CrossRef - Occurrence and molecular characterisation of Vibrio parahaemolyticus in crustaceans commercialised in Venice area, Italy
Greta Caburlotto, Elisabetta Suffredini, Marica Toson, Luca Fasolato, Paolo Antonetti, Michela Zambon, Amedeo Manfrin
International Journal of Food Microbiology.2016; 220: 39. CrossRef - Population Relationship ofVibrio parahaemolyticusIsolates Derived from Aquaculture Ponds, a Seafood Market, Restaurants, and Clinical Samples
Lei Gao, Yi qin Deng, Chang Chen, Chang wen Ke, Bo sheng Li, Yun ying Long, Zhu hong Liu, Lu Wei
Foodborne Pathogens and Disease.2016; 13(6): 333. CrossRef - Genomic evidence of adaptive evolution in emergent Vibrio parahaemolyticus ecotypes
Jeffrey W. Turner, Chris T. Berthiaume, Rhonda Morales, E. Virginia Armbrust, Mark S. Strom, Jody W. Deming, Erin Lipp
Elementa: Science of the Anthropocene.2016;[Epub] CrossRef - Insights into the environmental reservoir of pathogenic Vibrio parahaemolyticus using comparative genomics
Tracy H. Hazen, Patricia C. Lafon, Nancy M. Garrett, Tiffany M. Lowe, Daniel J. Silberger, Lori A. Rowe, Michael Frace, Michele B. Parsons, Cheryl A. Bopp, David A. Rasko, Patricia A. Sobecky
Frontiers in Microbiology.2015;[Epub] CrossRef - The small RNA Spot 42 regulates the expression of the type III secretion system 1 (T3SS1) chaperone protein VP1682 inVibrio parahaemolyticus
Tomotaka Tanabe, Katsushiro Miyamoto, Hiroshi Tsujibo, Shigeo Yamamoto, Tatsuya Funahashi, Olga Ozoline
FEMS Microbiology Letters.2015; 362(21): fnv173. CrossRef - Role of VcrD1 protein in expression and secretion of flagellar components in Vibrio parahaemolyticus
Hyeon Jin Noh, Sara Nagami, Min Jung Kim, Juri Kim, Na Kyung Lee, Kyu-Ho Lee, Soon-Jung Park
Archives of Microbiology.2015; 197(3): 397. CrossRef - The pathogenesis, detection, and prevention of Vibrio parahaemolyticus
Rongzhi Wang, Yanfang Zhong, Xiaosong Gu, Jun Yuan, Abdullah F. Saeed, Shihua Wang
Frontiers in Microbiology.2015;[Epub] CrossRef - VvpM, an extracellular metalloprotease of Vibrio vulnificus, induces apoptotic death of human cells
Mi-Ae Lee, Jeong-A Kim, Yu Jin Yang, Mee-Young Shin, Soon-Jung Park, Kyu-Ho Lee
Journal of Microbiology.2014; 52(12): 1036. CrossRef - Intracellular Vibrio parahaemolyticus Escapes the Vacuole and Establishes a Replicative Niche in the Cytosol of Epithelial Cells
Marcela de Souza Santos, Kim Orth, Jeff F. Miller
mBio.2014;[Epub] CrossRef - Effectors of animal and plant pathogens use a common domain to bind host phosphoinositides
Dor Salomon, Yirui Guo, Lisa N. Kinch, Nick V. Grishin, Kevin H. Gardner, Kim Orth
Nature Communications.2013;[Epub] CrossRef - Development of a Real-Time Resistance Measurement for Vibrio parahaemolyticus Detection by the Lecithin-Dependent Hemolysin Gene
Guiming Xiang, Xiaoyun Pu, Dongneng Jiang, Linlin Liu, Chang Liu, Xiaobo Liu, Richard C. Willson
PLoS ONE.2013; 8(8): e72342. CrossRef
Research Support, Non-U.S. Gov'ts
- Reliability of Non-Culturable Virus Monitoring by PCR-Based Detection Methods in Environmental Waters Containing Various Concentrations of Target RNA
-
Eung Seo Koo , Chang-Hoon Yoo , Youjin Na , Soo Young Park , Hey Rhyoung Lyoo , Yong Seok Jeong
-
J. Microbiol. 2012;50(5):726-734. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2279-y
-
-
175
View
-
0
Download
-
9
Scopus
-
Abstract
-
Owing to the lack of practical cell culture system for human noroviruses (HuNoV), various detection methods based on conventional reverse transcription-PCR (RT-PCR) and the quantitative real-time PCR have been major tools for monitoring environmental water safety. In this study, we showed that the proportion of water sample concentrates used for one-step RT-PCR significantly influences false-negative findings of the non-culturable viruses. In total, 59 archived samples of previously analyzed water concentrates were reexamined for HuNoV RNA by the one-step RT-PCR and semi-nested PCR. Using new aliquots for RNA extraction for every trial, up to 20 PCR trials were performed for each archive to determine whether the crosscheck results supported the previous determinations. We reconfirmed that 27.6% (8/29) of the samples were HuNoV-positive samples: 6.7% (1/15) from groundwater, 33.3% (3/9) from river water, and 80% (4/5) from treated sewage effluent (TSE). These results corresponded to the ratio of previously negative HuNoV samples now identified as positive (8/30): 6.7% (1/15) from groundwater, 20% (1/5) from river water, and 60% (6/10) from TSE. To elucidate the cause of these results, 16 different concentrations of murine norovirus (MNV) RNA (from 2×102 to 8×103 copies, divided into 10 tubes for each concentration) were subjected to one-step RT-PCR. The detection frequency and reproducibility decreased sharply when the number of MNV RNA copies fell below threshold levels. These observations suggest that the proportion of water concentrate used for PCR-based detection should be considered carefully when deciding viral presence in certain types of environmental water, particularly in regard with legal controls.
- Pyrosequencing Analysis of the Bacterial Communities in the Guts of Honey Bees Apis cerana and Apis mellifera in Korea
-
Jae-Hyung Ahn , In-Pyo Hong , Jeung-Im Bok , Byung-Yong Kim , Jaekyeong Song , Hang-Yeon Weon
-
J. Microbiol. 2012;50(5):735-745. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2188-0
-
-
201
View
-
0
Download
-
84
Crossref
-
Abstract
-
The bacterial communities in the guts of the adults and larvae of the Asian honey bee Apis cerana and the European honey bee Apis mellifera were surveyed by pyrosequencing the 16S rRNA genes. Most of the gut bacterial 16S rRNA gene sequences were highly similar to the known honey bee-specific ones and affiliated with Pasteurellaceae or lactic acid bacteria (LAB). The numbers of operational taxonomic units (OTUs, defined at 97% similarity) were lower in the larval guts (6 or 9) than in the adult guts (18 or 20), and the frequencies of Pasteurellaceae-related OTUs were higher in the larval guts while those of LAB-related OTUs in the adult guts. The frequencies of Lactococcus, Bartonella, Spiroplasma, Enterobacteriaceae, and Flavobacteriaceae-related OTUs were much higher in A. cerana guts while Bifidobacterium and Lachnospiraceae-related OTUs were more abundant in A. mellfera guts. The bacterial community structures in the midguts and hindguts of the adult honey bees were not different for A. cerana, but significantly different for A. mellifera. The above results substantiated the previous observation that honey bee guts are dominated by several specific bacterial groups, and also showed that the relative abundances of OTUs could be markedly changed depending on the developmental stage, the location within the gut, and the honey bee species. The possibility of using the gut bacterial community as an indicator of honey bee health was discussed.
-
Citations
Citations to this article as recorded by

- Characterization of gut microbiota in Apis cerana Across different altitudes in the Peninsular India
K. Hariprasath, M. Dhanvarsha, S. Mohankumar, M. Sudha, N. Saranya, V. R. Saminathan, S. Subramanian
BMC Ecology and Evolution.2025;[Epub] CrossRef - High abundance of lactobacilli in the gut microbiome of honey bees during winter
Gagandeep Brar, Lyna Ngor, Quinn S. McFrederick, Alex S. Torson, Arun Rajamohan, Joesph Rinehart, Preetpal Singh, Julia H. Bowsher
Scientific Reports.2025;[Epub] CrossRef - Host Plant Dependence of the Symbiotic Microbiome of the Gall-Inducing Wasp Trichagalma acutissimae
Yingnan Wang, Yuanchen Zhang, Ran Li, Yujian Li, Muha Cha, Xianfeng Yi
Insects.2025; 16(7): 652. CrossRef - Bacterial diversity in honey bee environment: Embu County, Kenya
James K. Njoroge, Moses Njire, Julianna Maina, Romano Mwirichia, Franklin N. Nyabuga, Julius Mugweru
Scientific African.2024; 23: e02036. CrossRef - Comprehensive analysis of the microbiome in Apis cerana honey highlights honey as a potential source for the isolation of beneficial bacterial strains
Pham T. Lanh, Bui T.T. Duong, Ha T. Thu, Nguyen T. Hoa, Dong Van Quyen
PeerJ.2024; 12: e17157. CrossRef -
Impacts of
Apis cerana
gut microbes on
Nosema ceranae
proliferation in
Apis mellifera
Zhihao Wu, Xiuxiu Wei, Lizhen Zhang, Zhijiang Zeng, Weiyu Yan, Qiang Huang
Journal of Apicultural Research.2024; 63(4): 694. CrossRef - Analyzing Gut Microbial Community in Varroa destructor-Infested Western Honeybee (Apis mellifera)
Minji Kim, Woo Jae Kim, Soo-Je Park
Journal of Microbiology and Biotechnology.2023; 33(11): 1495. CrossRef - Microbial Diversity in Bee Species and Bee Products: Pseudomonads Contribution to Bee Well-Being and the Biological Activity Exerted by Honey Bee Products: A Narrative Review
Christina Tsadila, Chiara Amoroso, Dimitris Mossialos
Diversity.2023; 15(10): 1088. CrossRef - Infestation of Apis mellifera workers and larvae with Varroa destructor affects gut bacterial diversity
F.F. Abuldahab, M.F. Abd-ElAziz, Y.A. El-Sayed, M.S. Abdallah, S.H. Mahmoud
Journal of Entomological and Acarological Research.2022;[Epub] CrossRef - Toward global integration of biodiversity big data: a harmonized metabarcode data generation module for terrestrial arthropods
Paula Arribas, Carmelo Andújar, Kristine Bohmann, Jeremy R deWaard, Evan P Economo, Vasco Elbrecht, Stefan Geisen, Marta Goberna, Henrik Krehenwinkel, Vojtech Novotny, Lucie Zinger, Thomas J Creedy, Emmanouil Meramveliotakis, Víctor Noguerales, Isaac Over
GigaScience.2022;[Epub] CrossRef - Isolation, Identification, and Analysis of Potential Functions of Culturable Bacteria Associated with an Invasive Gall Wasp, Leptocybe invasa
Yipeng Liu, Letian Xu, Zhouqiong Zhang, Zongyou Huang, Dongxue Fang, Xialin Zheng, Zhende Yang, Min Lu
Microbial Ecology.2022; 83(1): 151. CrossRef - Gut Bacterial Flora of Open Nested Honeybee, Apis florea
D. N. Ganeshprasad, Jafar K. Lone, Kunal Jani, Yogesh S. Shouche, Khalid Ali Khan, Samy Sayed, Mustafa Shukry, Showket A. Dar, Muntazir Mushtaq, A. H. Sneharani
Frontiers in Ecology and Evolution.2022;[Epub] CrossRef - Potensi Probiotik Bakteri Asam Laktat Asal Madu dari Tiga Jenis Lebah yang Berbeda
Iffa Illiyya Fatma, Lilis Nuraida, Didah Nur Faridah
Jurnal Teknologi dan Industri Pangan.2022; 33(2): 189. CrossRef - Biodiversity of lactic acid bacteria of wild honey bee and Sumbawa horse milk by using RAPD-PCR
A Prastyowati, A Z Mustopa, M Faiz, A B Manguntungi, Fatimah, K A Fidien
IOP Conference Series: Earth and Environmental Science.2021; 762(1): 012001. CrossRef - Amplicon Sequencing of Variable 16S rRNA from Bacteria and ITS2 Regions from Fungi and Plants, Reveals Honeybee Susceptibility to Diseases Results from Their Forage Availability under Anthropogenic Landscapes
Aneta A. Ptaszyńska, Przemyslaw Latoch, Paul J. Hurd, Andrew Polaszek, Joanna Michalska-Madej, Łukasz Grochowalski, Dominik Strapagiel, Sebastian Gnat, Daniel Załuski, Marek Gancarz, Robert Rusinek, Patcharin Krutmuang, Raquel Martín Hernández, Mariano Hi
Pathogens.2021; 10(3): 381. CrossRef - Gut Microbiome of Two Different Honeybee Workers Subspecies In Saudi Arabia.
Marfat Alatawy, Sanaa G. Al-Attas, Ahmad I. Assagaf, Rashad R. Al-Hindi, Khalid M. Alghamdi, Jazem A. Mahyoub, Alshehri D, Al-Amrah H, Alatawi H, Edris S, Ahmed Bahieldin
Biosciences Biotechnology Research Asia.2021; 17(4): 659. CrossRef - Foodomics in bee product research: a systematic literature review
Ioannis Kafantaris, Grigoris D. Amoutzias, Dimitris Mossialos
European Food Research and Technology.2021; 247(2): 309. CrossRef - Honeybee Exposure to Veterinary Drugs: How Is the Gut Microbiota Affected?
Loredana Baffoni, Daniele Alberoni, Francesca Gaggìa, Chiara Braglia, Catherine Stanton, Paul R. Ross, Diana Di Gioia, Christina A. Cuomo
Microbiology Spectrum.2021;[Epub] CrossRef - Bacterial diversity of Leptocybe invasa Fisher & La Salle (Hymenoptera: Eulophidae) from different geographical conditions in China
Chunhui Guo, Xin Peng, Hantang Wang, Xialin Zheng, Ping Hu, Jing Zhou, Zhirou Ding, Xue Wang, Zhende Yang
Archives of Insect Biochemistry and Physiology.2021;[Epub] CrossRef - Gut Bacteria Associated With Monochamus saltuarius (Coleoptera: Cerambycidae) and Their Possible Roles in Host Plant Adaptations
Si-Xun Ge, Feng-Ming Shi, Jia-He Pei, Ze-Hai Hou, Shi-Xiang Zong, Li-Li Ren
Frontiers in Microbiology.2021;[Epub] CrossRef - Bombilactobacillus apium sp. nov., isolated from the gut of honeybee (Apis cerana)
Jong-Pyo Kang, Yue Huo, Van-An Hoang, Dong-Uk Yang, Deok-Chun Yang, Se-Chan Kang
Archives of Microbiology.2021; 203(5): 2193. CrossRef - Bacterial Communities Associated with the Pine Wilt Disease Insect Vector Monochamus alternatus (Coleoptera: Cerambycidae) during the Larvae and Pupae Stages
Hongjian Chen, Dejun Hao, Zhiqiang Wei, Lujie Wang, Tao Lin
Insects.2020; 11(6): 376. CrossRef - Impact of Sacbrood Virus on Larval Microbiome of Apis mellifera and Apis cerana
Rujipas Yongsawas, Veeranan Chaimanee, Jeffery S. Pettis, Humberto Freire Boncristiani Junior, Dawn Lopez, Ammarin In-on, Panuwan Chantawannakul, Terd Disayathanoowat
Insects.2020; 11(7): 439. CrossRef - Characterization of the Kenyan Honey Bee (Apis mellifera) Gut Microbiota: A First Look at Tropical and Sub-Saharan African Bee Associated Microbiomes
Yosef Hamba Tola, Jacqueline Wahura Waweru, Gregory D. D. Hurst, Bernard Slippers, Juan C. Paredes
Microorganisms.2020; 8(11): 1721. CrossRef - Comparison of bacterial diversity and abundance between sexes of Leptocybe invasa Fisher & La Salle (Hymenoptera: Eulophidae) from China
Chunhui Guo, Xin Peng, Xialin Zheng, Xiaoyun Wang, Ruirui Wang, Zongyou Huang, Zhende Yang
PeerJ.2020; 8: e8411. CrossRef - BAL ARILARINDA GASTROİNTESTİNAL BAKTERİYEL FLORA
Şengül Alpay Karaoğlu, Şeyma Suyabatmaz, Arif Bozdeveci
Uludağ Arıcılık Dergisi.2020; 20(1): 97. CrossRef - Comparative genomics of Lactobacillus species as bee symbionts and description of Lactobacillus bombintestini sp. nov., isolated from the gut of Bombus ignitus
Jun Heo, Soo-Jin Kim, Jeong-Seon Kim, Seung-Beom Hong, Soon-Wo Kwon
Journal of Microbiology.2020; 58(6): 445. CrossRef - Different Dynamics of Bacterial and Fungal Communities in Hive-Stored Bee Bread and Their Possible Roles: A Case Study from Two Commercial Honey Bees in China
Terd Disayathanoowat, HuanYuan Li, Natapon Supapimon, Nakarin Suwannarach, Saisamorn Lumyong, Panuwan Chantawannakul, Jun Guo
Microorganisms.2020; 8(2): 264. CrossRef - Honeybee gut microbiota dysbiosis in pesticide/parasite co-exposures is mainly induced by Nosema ceranae
Laurianne Paris, Elodie Peghaire, Anne Moné, Marie Diogon, Didier Debroas, Frédéric Delbac, Hicham El Alaoui
Journal of Invertebrate Pathology.2020; 172: 107348. CrossRef - Structural diversity and functional variability of gut microbial communities associated with honey bees
Khalid Ali Khan, Ahmad A. Al-Ghamdi, Hamed A. Ghramh, Mohammad Javed Ansari, Habib Ali, Saad A. Alamri, Saad Naser Al- Kahtani, Nuru Adgaba, Muhammad Qasim, Muhammad Hafeez
Microbial Pathogenesis.2020; 138: 103793. CrossRef - In Vitro Antagonistic Effect of Gut Bacteriota Isolated from Indigenous Honey Bees and Essential Oils against Paenibacillus Larvae
Miroslava Kačániová, Margarita Terentjeva, Jana Žiarovská, Przemysław Łukasz Kowalczewski
International Journal of Molecular Sciences.2020; 21(18): 6736. CrossRef - Microbial Diversity Associated with the Pollen Stores of Captive-Bred Bumble Bee Colonies
Prarthana S. Dharampal, Luis Diaz-Garcia, Max A. B. Haase, Juan Zalapa, Cameron R. Currie, Chris Todd Hittinger, Shawn A. Steffan
Insects.2020; 11(4): 250. CrossRef - Investigation of the gut microbiome of Apis cerana honeybees from Vietnam
Bui Thi Thuy Duong, Nguyen Thi Kim Lien, Ha Thi Thu, Nguyen Thi Hoa, Pham Thi Lanh, Bo-Ram Yun, Mi-Sun Yoo, Yun Sang Cho, Dong Van Quyen
Biotechnology Letters.2020; 42(11): 2309. CrossRef - The honey bee gut microbiota: strategies for study and characterization
S. Romero, A. Nastasa, A. Chapman, W. K. Kwong, L. J. Foster
Insect Molecular Biology.2019; 28(4): 455. CrossRef - Effect of transient exposure to carbaryl wettable powder on the gut microbial community of honey bees
Kathyleen Nogrado, Seul Lee, Kyongmi Chon, Ji-Hoon Lee
Applied Biological Chemistry.2019;[Epub] CrossRef - In-hive variation of the gut microbial composition of honey bee larvae and pupae from the same oviposition time
Zuzana Hroncova, Jiri Killer, Josef Hakl, Dalibor Titera, Jaroslav Havlik
BMC Microbiology.2019;[Epub] CrossRef - The effect of Bt Cry9Ee toxin on honey bee brood and adults reared in vitro, Apis mellifera (Hymenoptera: Apidae)
Pingli Dai, Mengyue Wang, Lili Geng, Zhenxiong Yan, Yang Yang, Lin Guo, Shilong Ma, Qingyun Diao
Ecotoxicology and Environmental Safety.2019; 181: 381. CrossRef - Modulation of the honey bee queen microbiota: Effects of early social contact
J. Elijah Powell, Daren Eiri, Nancy A. Moran, Juliana Rangel, Daniel E. Rozen
PLOS ONE.2018; 13(7): e0200527. CrossRef - Genome Sequences of Apibacter spp., Gut Symbionts of Asian Honey Bees
Waldan K Kwong, Margaret I Steele, Nancy A Moran, Tal Dagan
Genome Biology and Evolution.2018; 10(4): 1174. CrossRef - The Antimicrobial Potential of Bacteria Isolated from Honey Samples Produced in the Apiaries Located in Pomeranian Voivodeship in Northern Poland
Magdalena Pajor, Randy W. Worobo, Sławomir Milewski, Piotr Szweda
International Journal of Environmental Research and Public Health.2018; 15(9): 2002. CrossRef - The Herbicide Glyphosate Negatively Affects Midgut Bacterial Communities and Survival of Honey Bee during Larvae Reared in Vitro
Pingli Dai, Zhenxiong Yan, Shilong Ma, Yang Yang, Qiang Wang, Chunsheng Hou, Yanyan Wu, Yongjun Liu, Qingyun Diao
Journal of Agricultural and Food Chemistry.2018; 66(29): 7786. CrossRef - Isolation of β-1,3-Glucanase-Producing Microorganisms from Poria cocos Cultivation Soil via Molecular Biology
Qiulan Wu, Xin Dou, Qi Wang, Zhengbing Guan, Yujie Cai, Xiangru Liao
Molecules.2018; 23(7): 1555. CrossRef - Characterization of gut bacterial flora of Apis mellifera from north-west Pakistan
Syed Ishtiaq Anjum, Abdul Haleem Shah, Muhammad Aurongzeb, Junaid Kori, M. Kamran Azim, Mohammad Javed Ansari, Li Bin
Saudi Journal of Biological Sciences.2018; 25(2): 388. CrossRef - Bacterial community composition in the salivary glands of triatomines (Hemiptera: Reduviidae)
Michele Souza Lima, Marinella Silva Laport, Elias Seixas Lorosa, José Jurberg, Kátia Regina Netto dos Santos, Mário Alberto Cardoso da Silva Neto, Caio Tavora Coelho da Costa Rachid, Georgia Correa Atella, Luciano Andrade Moreira
PLOS Neglected Tropical Diseases.2018; 12(9): e0006739. CrossRef -
Influence of Feeding Type and
Nosema ceranae
Infection on the Gut Microbiota of
Apis cerana
Workers
Shao K. Huang, Kun T. Ye, Wei F. Huang, Bi H. Ying, Xin Su, Li H. Lin, Jiang H. Li, Yan P. Chen, Ji L. Li, Xiu L. Bao, Jian Z. Hu, Ashley Shade
mSystems.2018;[Epub] CrossRef - Bacterial communities associated with honeybee food stores are correlated with land use
Philip Donkersley, Glenn Rhodes, Roger W. Pickup, Kevin C. Jones, Kenneth Wilson
Ecology and Evolution.2018; 8(10): 4743. CrossRef - Effects of diet type, developmental stage, and gut compartment in the gut bacterial communities of two Cerambycidae species (Coleoptera)
Jeong Myeong Kim, Min-Young Choi, Jae-Woo Kim, Shin Ae Lee, Jae-Hyung Ahn, Jaekyeong Song, Seong-Hyun Kim, Hang-Yeon Weon
Journal of Microbiology.2017; 55(1): 21. CrossRef - Investigation of gut microbial communities associated with indigenous honey bee ( Apis mellifera jemenitica ) from two different eco-regions of Saudi Arabia
Khalid Ali Khan, Mohammad Javed Ansari, Ahmad Al-Ghamdi, Adgaba Nuru, Steve Harakeh, Javaid Iqbal
Saudi Journal of Biological Sciences.2017; 24(5): 1061. CrossRef - Immune system stimulation by the gut symbiont Frischella perrara in the honey bee (Apis mellifera)
Olivier Emery, Konstantin Schmidt, Philipp Engel
Molecular Ecology.2017; 26(9): 2576. CrossRef - No effect of Bt Cry1Ie toxin on bacterial diversity in the midgut of the Chinese honey bees, Apis cerana cerana (Hymenoptera, Apidae)
Hui-Ru Jia, Ping-Li Dai, Li-Li Geng, Cameron J. Jack, Yun-He Li, Yan-Yan Wu, Qing-Yun Diao, James D. Ellis
Scientific Reports.2017;[Epub] CrossRef - Colony Collapse Disorder (CCD) and bee age impact honey bee pathophysiology
Dennis vanEngelsdorp, Kirsten S. Traynor, Michael Andree, Elinor M. Lichtenberg, Yanping Chen, Claude Saegerman, Diana L. Cox-Foster, Guy Smagghe
PLOS ONE.2017; 12(7): e0179535. CrossRef - Honey bee gut microbial communities are robust to the fungicide Pristine® consumed in pollen
Gloria DeGrandi-Hoffman, Vanessa Corby-Harris, Emily Watkins DeJong, Mona Chambers, Geoffrey Hidalgo
Apidologie.2017; 48(3): 340. CrossRef - Midgut bacterial communities in the giant Asian honeybee (Apis dorsata) across 4 developmental stages: A comparative study
Prakaimuk Saraithong, Yihong Li, Kanokporn Saenphet, Zhou Chen, Panuwan Chantawannakul
Insect Science.2017; 24(1): 81. CrossRef - The Microbial Community Dynamics during the Vitex Honey Ripening Process in the Honeycomb
Yaqin Wen, Lin Wang, Yue Jin, Jinzhen Zhang, Lei Su, Xiaoling Zhang, Jinhui Zhou, Yi Li
Frontiers in Microbiology.2017;[Epub] CrossRef - The Gut Microbiomes of Two Pachysoma MacLeay Desert Dung Beetle Species (Coleoptera: Scarabaeidae: Scarabaeinae) Feeding on Different Diets
Philippa Z. N. Franzini, Jean-Baptiste Ramond, Clarke H. Scholtz, Catherine L. Sole, Sandra Ronca, Don A. Cowan, Robert J Forster
PLOS ONE.2016; 11(8): e0161118. CrossRef - Soil pH and electrical conductivity are key edaphic factors shaping bacterial communities of greenhouse soils in Korea
Jeong Myeong Kim, An-Sung Roh, Seung-Chul Choi, Eun-Jeong Kim, Moon-Tae Choi, Byung-Koo Ahn, Sun-Kuk Kim, Young-Han Lee, Jae-Ho Joa, Seong-Soo Kang, Shin Ae Lee, Jae-Hyung Ahn, Jaekyeong Song, Hang-Yeon Weon
Journal of Microbiology.2016; 54(12): 838. CrossRef - The effects of Bt Cry1Ie toxin on bacterial diversity in the midgut of Apis mellifera ligustica (Hymenoptera: Apidae)
Hui-Ru Jia, Li-Li Geng, Yun-He Li, Qiang Wang, Qing-Yun Diao, Ting Zhou, Ping-Li Dai
Scientific Reports.2016;[Epub] CrossRef - Apibacter adventoris gen. nov., sp. nov., a member of the phylum Bacteroidetes isolated from honey bees
Waldan K. Kwong, Nancy A. Moran
International Journal of Systematic and Evolutionary Microbiology.2016; 66(3): 1323. CrossRef - Gut microbial communities of social bees
Waldan K. Kwong, Nancy A. Moran
Nature Reviews Microbiology.2016; 14(6): 374. CrossRef - Ecological Succession in the Honey Bee Gut: Shift in Lactobacillus Strain Dominance During Early Adult Development
Kirk E. Anderson, Pedro A. P. Rodrigues, Brendon M. Mott, Patrick Maes, Vanessa Corby-Harris
Microbial Ecology.2016; 71(4): 1008. CrossRef - Beyond 16S rRNA Community Profiling: Intra-Species Diversity in the Gut Microbiota
Kirsten M. Ellegaard, Philipp Engel
Frontiers in Microbiology.2016;[Epub] CrossRef - Dynamics of bacterial communities in rice field soils as affected by different long-term fertilization practices
Jae-Hyung Ahn, Shin Ae Lee, Jeong Myeong Kim, Myung-Sook Kim, Jaekyeong Song, Hang-Yeon Weon
Journal of Microbiology.2016; 54(11): 724. CrossRef - Bartonella apis sp. nov., a honey bee gut symbiont of the class Alphaproteobacteria
Lucie Kešnerová, Roxane Moritz, Philipp Engel
International Journal of Systematic and Evolutionary Microbiology.2016; 66(1): 414. CrossRef - Extensive intra-phylotype diversity in lactobacilli and bifidobacteria from the honeybee gut
Kirsten M Ellegaard, Daniel Tamarit, Emelie Javelind, Tobias C Olofsson, Siv GE Andersson, Alejandra Vásquez
BMC Genomics.2015;[Epub] CrossRef - Bacterial community structure in Apis florea larvae analyzed by denaturing gradient gel electrophoresis and 16S rRNA gene sequencing
Prakaimuk Saraithong, Yihong Li, Kanokporn Saenphet, Zhou Chen, Panuwan Chantawannakul
Insect Science.2015; 22(5): 606. CrossRef - Genomics of the honey bee microbiome
Nancy A Moran
Current Opinion in Insect Science.2015; 10: 22. CrossRef - Carpoglyphus lactis(Acari: Astigmata) from various dried fruits differed in associated micro-organisms
J. Hubert, M. Nesvorná, J. Kopecký, M. Ságová-Marečková, P. Poltronieri
Journal of Applied Microbiology.2015; 118(2): 470. CrossRef - Characterization of gut bacteria at different developmental stages of Asian honey bees, Apis cerana
Jun Guo, Jie Wu, Yanping Chen, Jay D. Evans, Rongguo Dai, Wenhua Luo, Jilian Li
Journal of Invertebrate Pathology.2015; 127: 110. CrossRef - Bacteria detected in the honeybee parasitic miteVarroa destructorcollected from beehive winter debris
J. Hubert, T. Erban, M. Kamler, J. Kopecky, M. Nesvorna, S. Hejdankova, D. Titera, J. Tyl, L. Zurek
Journal of Applied Microbiology.2015; 119(3): 640. CrossRef - The Bacterium Frischella perrara Causes Scab Formation in the Gut of its Honeybee Host
Philipp Engel, Kelsey D. Bartlett, Nancy A. Moran, Margaret J. McFall-Ngai
mBio.2015;[Epub] CrossRef - Detection of Spiroplasma melliferum in honey bee colonies in the US
Huo-Qing Zheng, Yan Ping Chen
Journal of Invertebrate Pathology.2014; 119: 47. CrossRef - The Bacterial Communities Associated with Honey Bee (Apis mellifera) Foragers
Vanessa Corby-Harris, Patrick Maes, Kirk E. Anderson, Nicole M. Gerardo
PLoS ONE.2014; 9(4): e95056. CrossRef - Deodorization of pig slurry and characterization of bacterial diversity using 16S rDNA sequence analysis
Ok-Hwa Hwang, Sebastian Raveendar, Young-Ju Kim, Ji-Hun Kim, Tae-Hun Kim, Dong-Yoon Choi, Che Ok Jeon, Sung-Back Cho, Kyung-Tai Lee
Journal of Microbiology.2014; 52(11): 918. CrossRef - Hive‐stored pollen of honey bees: many lines of evidence are consistent with pollen preservation, not nutrient conversion
Kirk E. Anderson, Mark J. Carroll, Tim Sheehan, Brendon M. Mott, Patrick Maes, Vanessa Corby‐Harris
Molecular Ecology.2014; 23(23): 5904. CrossRef - Host species and developmental stage, but not host social structure, affects bacterial community structure in socially polymorphic bees
Quinn S. McFrederick, William T. Wcislo, Michael C. Hout, Ulrich G. Mueller
FEMS Microbiology Ecology.2014; 88(2): 398. CrossRef - Acinetobacter apis sp. nov., isolated from the intestinal tract of a honey bee, Apis mellifera
Pil Soo Kim, Na-Ri Shin, Joon Yong Kim, Ji-Hyun Yun, Dong-Wook Hyun, Jin-Woo Bae
Journal of Microbiology.2014; 52(8): 639. CrossRef - Hidden Diversity in Honey Bee Gut Symbionts Detected by Single-Cell Genomics
Philipp Engel, Ramunas Stepanauskas, Nancy A. Moran, Paul M. Richardson
PLoS Genetics.2014; 10(9): e1004596. CrossRef - High-grain feeding alters caecal bacterial microbiota composition and fermentation and results in caecal mucosal injury in goats
Junhua Liu, Tingting Xu, Weiyun Zhu, Shengyong Mao
British Journal of Nutrition.2014; 112(3): 416. CrossRef - Routes of Acquisition of the Gut Microbiota of the Honey Bee Apis mellifera
J. Elijah Powell, Vincent G. Martinson, Katherine Urban-Mead, Nancy A. Moran, H. Goodrich-Blair
Applied and Environmental Microbiology.2014; 80(23): 7378. CrossRef - Cultivable microorganisms associated with honeys of different geographical and botanical origin
Milko Sinacori, Nicola Francesca, Antonio Alfonzo, Margherita Cruciata, Ciro Sannino, Luca Settanni, Giancarlo Moschetti
Food Microbiology.2014; 38: 284. CrossRef -
Interactions between fungi and bacteria influence microbial community structure in the
Megachile rotundata
larval gut
Quinn S. McFrederick, Ulrich G. Mueller, Rosalind R. James
Proceedings of the Royal Society B: Biological Sciences.2014; 281(1779): 20132653. CrossRef - Standard methods for research onApis melliferagut symbionts
Philipp Engel, Rosalind R James, Ryuichi Koga, Waldan K Kwong, Quinn S McFrederick, Nancy A Moran
Journal of Apicultural Research.2013; 52(4): 1. CrossRef - Comprehensive Bee Pathogen Screening in Belgium Reveals Crithidia mellificae as a New Contributory Factor to Winter Mortality
Jorgen Ravoet, Jafar Maharramov, Ivan Meeus, Lina De Smet, Tom Wenseleers, Guy Smagghe, Dirk C. de Graaf, Yi Li
PLoS ONE.2013; 8(8): e72443. CrossRef - Effects of PCR cycle number and DNA polymerase type on the 16S rRNA gene pyrosequencing analysis of bacterial communities
Jae-Hyung Ahn, Byung-Yong Kim, Jaekyeong Song, Hang-Yeon Weon
Journal of Microbiology.2012; 50(6): 1071. CrossRef
Journal Article
- Comparative Study of Olive Oil Mill Wastewater Treatment Using Free and Immobilized Coriolopsis polyzona and Pycnoporus coccineus
-
Mohamed Neifar , Atef Jaouani , María Jesús Martínez , Michel J. Penninckx
-
J. Microbiol. 2012;50(5):746-753. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2079-4
-
-
237
View
-
0
Download
-
6
Crossref
-
Abstract
-
The efficiency of the two white-rot fungi Pycnoporus coccineus and Coriolopsis polyzona in the Olive Oil Mill Wastewater (OOMW) treatment was investigated. Both fungi were active in the decolourisation and COD removal of OOMW at 50 g/L COD, but only the first fungus remains effective on the crude effluent (COD=100 g/L). Moreover P. coccineus was less affected by oxygen supplementation and exhibited a high tolerance to agitation in comparison to C. polyzona. However, it required a nitrogen supplementation to obtain faster and higher COD removal. To overcome the negative effect of agitation on fungi growth and efficiency, immobilisation of C. polyzona and P. coccineus in polyurethane foam was applied. The immobilized system showed better COD decreases during three consecutive batches without remarkable loss of performances. The results obtained in this study suggested that immobilized C. polyzona and especially immobilized P. coccineus might be applicable to a large scale for the removal colour and COD of OOMW.
-
Citations
Citations to this article as recorded by

- Microalgae-based bioremediation of olive mill wastewater: Technical and environmental evaluations using orange peel and orange peel-derived biochar
Martina Lenzuni, Francesca Demichelis, Juan Felipe Basbus, Antonio Barbucci, Francesco Savorani, Tonia Tommasi, Alessandro Alberto Casazza
Sustainable Materials and Technologies.2025; 43: e01338. CrossRef - Detection Methods for Pine Wilt Disease: A Comprehensive Review
Sana Tahir, Syed Shaheer Hassan, Lu Yang, Miaomiao Ma, Chenghao Li
Plants.2024; 13(20): 2876. CrossRef - Treatment of olive mill wastewater through employing sequencing batch reactor: performance and microbial diversity assessment
Fatma Arous, Chadlia Hamdi, Souhir Kmiha, Nadia Khammassi, Amani Ayari, Mohamed Neifar, Tahar Mechichi, Atef Jaouani
3 Biotech.2018;[Epub] CrossRef - Immobilization of white rot fungi to carbohydrate-rich corn cob as a basis for tertiary treatment of secondarily treated pulp and paper mill wastewater
Anlong Zhang, Guiqiu Wang, Guoli Gong, Jing Shen
Industrial Crops and Products.2017; 109: 538. CrossRef - Optimization of Anthraquinone Dyes Decolorization Conditions with Response Surface Methodology by Aspergillus
Yufeng Ge, Bin Wei, Siyu Wang, Zhiguo Guo, Xiaolin Xu
Korean Chemical Engineering Research.2015; 53(3): 327. CrossRef - Deodorization of pig slurry and characterization of bacterial diversity using 16S rDNA sequence analysis
Ok-Hwa Hwang, Sebastian Raveendar, Young-Ju Kim, Ji-Hun Kim, Tae-Hun Kim, Dong-Yoon Choi, Che Ok Jeon, Sung-Back Cho, Kyung-Tai Lee
Journal of Microbiology.2014; 52(11): 918. CrossRef
Research Support, Non-U.S. Gov'ts
- Characterization of the Bacterial and Archaeal Communities in Rice Field Soils Subjected to Long-Term Fertilization Practices
-
Jae-Hyung Ahn , Jaekyeong Song , Byung-Yong Kim , Myung-Sook Kim , Jae-Ho Joa , Hang-Yeon Weon
-
J. Microbiol. 2012;50(5):754-765. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2409-6
-
-
181
View
-
0
Download
-
115
Scopus
-
Abstract
-
The bacterial and archaeal communities in rice field soils subjected to different fertilization regimes for 57 years were investigated in two different seasons, a non-planted, drained season (April) and a rice-growing, flooded season (August), by performing soil dehydrogenase assay, real-time PCR assay and pyrosequencing analysis. All fertilization regimes increased the soil dehydrogenase activity while the abundances of bacteria and archaea increased in the plots receiving inorganic fertilizers plus compost and not in those receiving inorganic fertilizers only. Rice-growing and flooding decreased the soil dehydrogenase activity while they increased the bacterial diversity in rice field soils. The bacterial communities were dominated by Chloroflexi, Proteobacteria, and Actinobacteria and the archaeal communities by Crenarchaeota at the phylum level. In principal coordinates analysis based on the weighted Fast UniFrac metric, the bacterial and archaeal communities were separated primarily by season, and generally distributed along with soil pH, the variation of which had been caused by long-term fertilization. Variations in the relative abundance according to the season or soil pH were observed for many bacterial and archaeal groups. In conclusion, the microbial activity, prokaryotic abundance and diversity, and prokaryotic community structure in the rice field soils were changed by season and long-term fertilization.
- PyroTrimmer: a Software with GUI for Pre-Processing 454 Amplicon Sequences
-
Jeongsu Oh , Byung Kwon Kim , Wan-Sup Cho , Soon Gyu Hong , Kyung Mo Kim
-
J. Microbiol. 2012;50(5):766-769. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2494-6
-
-
242
View
-
0
Download
-
21
Crossref
-
Abstract
-
The ultimate goal of metagenome research projects is to understand the ecological roles and physiological functions of the microbial communities in a given natural environment. The 454 pyrosequencing platform produces the longest reads among the most widely used next generation sequencing platforms. Since the relatively longer reads of the 454 platform provide more information for identification of microbial sequences, this platform is dedicated to microbial community and population studies. In order to accurately perform the downstream analysis of the 454 multiplex datasets, it is necessary to remove artificially designed sequences located at either ends of individual reads and to correct lowquality sequences. We have developed a program called Pyro-Trimmer that removes the barcodes, linkers, and primers, trims sequence regions with low quality scores, and filters out low-quality sequence reads. Although these functions have previously been implemented in other programs as well, PyroTrimmer has novelty in terms of the following features: i) more sensitive primer detection using Levenstein distance and global pairwise alignment, ii) the first stand-alone software with a graphic user interface, and iii) various options for trimming and filtering out the low-quality sequence reads. PyroTrimmer, written in JAVA, is compatible with multiple operating systems and can be downloaded free at http://pyrotrimmer.kobic.re.kr.
-
Citations
Citations to this article as recorded by

- Music of metagenomics—a review of its applications, analysis pipeline, and associated tools
Bilal Wajid, Faria Anwar, Imran Wajid, Haseeb Nisar, Sharoze Meraj, Ali Zafar, Mustafa Kamal Al-Shawaqfeh, Ali Riza Ekti, Asia Khatoon, Jan S. Suchodolski
Functional & Integrative Genomics.2022; 22(1): 3. CrossRef - Microbiome in Cladonia squamosa Is Vertically Stratified According to Microclimatic Conditions
Hyun-Ju Noh, Yung Mi Lee, Chae Haeng Park, Hong Kum Lee, Jang-Cheon Cho, Soon Gyu Hong
Frontiers in Microbiology.2020;[Epub] CrossRef - DNA Sequencing Technologies
Ka-Chun Wong, Jiao Zhang, Shankai Yan, Xiangtao Li, Qiuzhen Lin, Sam Kwong, Cheng Liang
ACM Computing Surveys.2020; 52(5): 1. CrossRef - Genomic Insight Into the Predominance of Candidate Phylum Atribacteria JS1 Lineage in Marine Sediments
Yung Mi Lee, Kyuin Hwang, Jae Il Lee, Mincheol Kim, Chung Yeon Hwang, Hyun-Ju Noh, Hakkyum Choi, Hong Kum Lee, Jongsik Chun, Soon Gyu Hong, Seung Chul Shin
Frontiers in Microbiology.2018;[Epub] CrossRef - Biogeochemical evidence of anaerobic methane oxidation on active submarine mud volcanoes on the continental slope of the Canadian Beaufort Sea
Dong-Hun Lee, Jung-Hyun Kim, Yung Mi Lee, Alina Stadnitskaia, Young Keun Jin, Helge Niemann, Young-Gyun Kim, Kyung-Hoon Shin
Biogeosciences.2018; 15(24): 7419. CrossRef - Niche specialization of bacteria in permanently ice‐covered lakes of the McMurdo Dry Valleys, Antarctica
Miye Kwon, Mincheol Kim, Cristina Takacs‐Vesbach, Jaejin Lee, Soon Gyu Hong, Sang Jong Kim, John C Priscu, Ok‐Sun Kim
Environmental Microbiology.2017; 19(6): 2258. CrossRef - Geographical structure of endosymbiotic bacteria hosted by Bathymodiolus mussels at eastern Pacific hydrothermal vents
Phuong-Thao Ho, Eunji Park, Soon Gyu Hong, Eun-Hye Kim, Kangchon Kim, Sook-Jin Jang, Robert C. Vrijenhoek, Yong-Jin Won
BMC Evolutionary Biology.2017;[Epub] CrossRef - Succession of bacterial community structure during the early stage of biofilm development in the Antarctic marine environment
Yung Mi Lee, Kyung Hee Cho, Kyuin Hwang, Eun Hye Kim, Mincheol Kim, Soon Gyu Hong, Hong Kum Lee
The Korean Journal of Microbiology.2016; 52(1): 49. CrossRef - Aboveground Whitefly Infestation-Mediated Reshaping of the Root Microbiota
Hyun G. Kong, Byung K. Kim, Geun C. Song, Soohyun Lee, Choong-Min Ryu
Frontiers in Microbiology.2016;[Epub] CrossRef - CLUSTOM-CLOUD: In-Memory Data Grid-Based Software for Clustering 16S rRNA Sequence Data in the Cloud Environment
Jeongsu Oh, Chi-Hwan Choi, Min-Kyu Park, Byung Kwon Kim, Kyuin Hwang, Sang-Heon Lee, Soon Gyu Hong, Arshan Nasir, Wan-Sup Cho, Kyung Mo Kim, Christophe Antoniewski
PLOS ONE.2016; 11(3): e0151064. CrossRef - Bacterial communities in Antarctic lichens
Chae Haeng Park, Kyung Mo Kim, Ok-Sun Kim, Gajin Jeong, Soon Gyu Hong
Antarctic Science.2016; 28(6): 455. CrossRef - Soil development and bacterial community shifts along the chronosequence of the Midtre Lovénbreen glacier foreland in Svalbard
Hye Young Kwon, Ji Young Jung, Ok-Sun Kim, Dominique Laffly, Hyoun Soo Lim, Yoo Kyung Lee
Journal of Ecology and Environment.2015; 38(4): 461. CrossRef - Improved pipeline for reducing erroneous identification by 16S rRNA sequences using the Illumina MiSeq platform
Yoon-Seong Jeon, Sang-Cheol Park, Jeongmin Lim, Jongsik Chun, Bong-Soo Kim
Journal of Microbiology.2015; 53(1): 60. CrossRef - Highly Heterogeneous Soil Bacterial Communities around Terra Nova Bay of Northern Victoria Land, Antarctica
Mincheol Kim, Ahnna Cho, Hyoun Soo Lim, Soon Gyu Hong, Ji Hee Kim, Joohan Lee, Taejin Choi, Tae Seok Ahn, Ok-Sun Kim, Jack Anthony Gilbert
PLOS ONE.2015; 10(3): e0119966. CrossRef - Algal and Fungal Diversity in Antarctic Lichens
Chae Haeng Park, Kyung Mo Kim, Arve Elvebakk, Ok‐Sun Kim, Gajin Jeong, Soon Gyu Hong
Journal of Eukaryotic Microbiology.2015; 62(2): 196. CrossRef - Bacterial community of sediments from the Australian-Antarctic ridge
Yung Mi Lee, Doshik Hahm, You-Jung Jung, Sung Hyun Park, Jongsik Chun, Soon Gyu Hong
Polar Biology.2014; 37(4): 587. CrossRef - Deodorization of pig slurry and characterization of bacterial diversity using 16S rDNA sequence analysis
Ok-Hwa Hwang, Sebastian Raveendar, Young-Ju Kim, Ji-Hun Kim, Tae-Hun Kim, Dong-Yoon Choi, Che Ok Jeon, Sung-Back Cho, Kyung-Tai Lee
Journal of Microbiology.2014; 52(11): 918. CrossRef - Effect of long-term different fertilization on bacterial community structures and diversity in citrus orchard soil of volcanic ash
Jae Ho Joa, Hang Yeon Weon, Hae Nam Hyun, Young Chull Jeun, Sang Wook Koh
Journal of Microbiology.2014; 52(12): 995. CrossRef - A metagenomics‐based approach to the top‐down effect on the detritivore food web: a salamanders influence on fungal communities within a deciduous forest
Donald M. Walker, Brandy R. Lawrence, Dakota Esterline, Sean P. Graham, Michael A. Edelbrock, Jessica A. Wooten
Ecology and Evolution.2014; 4(21): 4106. CrossRef - Differences in Gastric Mucosal Microbiota Profiling in Patients with Chronic Gastritis, Intestinal Metaplasia, and Gastric Cancer Using Pyrosequencing Methods
Chang Soo Eun, Byung Kwon Kim, Dong Soo Han, Seon Young Kim, Kyung Mo Kim, Bo Youl Choi, Kyu Sang Song, Yong Sung Kim, Jihyun F. Kim
Helicobacter.2014; 19(6): 407. CrossRef - Bacterial diversity in ornithogenic soils compared to mineral soils on King George Island, Antarctica
Ok-Sun Kim, Namyi Chae, Hyun Soo Lim, Ahnna Cho, Jeong Hoon Kim, Soon Gyu Hong, Jeongsu Oh
Journal of Microbiology.2012; 50(6): 1081. CrossRef
- Functional Characterization of the Genes tauO, tauK, and tauI in the Biosynthesis of Tautomycetin
-
Fen Wang , Rixiang Kong , Bo Liu , Jing Zhao , Rongguo Qiu , Li Tang
-
J. Microbiol. 2012;50(5):770-776. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2154-x
-
-
283
View
-
0
Download
-
4
Crossref
-
Abstract
-
Tautomycetin is a specific protein phosphatase I inhibitor. In an effort to elucidate the biosynthetic mechanism of tautomycetin, we inactivated genes of the tautomycetin biosynthetic gene cluster, tauI, tauO, and tauK, which encode for putative P450 oxidase, citryl-CoA lyase, and esterase enzymes, respectively. The mutant STQ0606 (ΔtauO) did not produce any detectable amount of tautomycetin intermediates but could convert dialkylmaleic anhydride to tautomycetin, strongly indicating that TauO was involved in dialkylmaleic anhydride biosynthesis. STQ1211 (ΔtauK) accumulated dialkylmaleic anhydride, whereas the cofermentation of STQ1211 (ΔtauK) and STQ0606 (ΔtauO) restored the production of tautomycetin. Together, these results suggest that TauK was responsible for the conjugation of dialkylmaleic anhydride and the polyketide moiety in tautomycetin biosynthesis. The disruption of tauI resulted in the accumulation of 5-des-ketotautomycetin, revealing that TauI was responsible for the oxidation at C5 as the last step. Although the shunt pathways were involved in the biosynthesis of tautomycetin, the main post-polyketide synthase tailoring steps were dehydration, decarboxylation and oxidation, taking place consecutively. This study allowed us to predict the biosynthesis of tautomycetin more accurately and provided novel insights into the mechanism of the biosynthesis of tautomycetin.
-
Citations
Citations to this article as recorded by

- Biocatalytic role of cytochrome P450s to produce antibiotics: A review
Anup Adhikari, Sajan Shakya, Shreesti Shrestha, Dipa Aryal, Kavi Prasad Timalsina, Dipesh Dhakal, Yogan Khatri, Niranjan Parajuli
Biotechnology and Bioengineering.2023; 120(12): 3465. CrossRef - Biosynthesis, regulation, and engineering of a linear polyketide tautomycetin: a novel immunosuppressant in Streptomyces sp. CK4412
Si-Sun Choi, Hee-Ju Nah, Hye-rim Pyeon, Eung-Soo Kim
Journal of Industrial Microbiology and Biotechnology.2017; 44(4-5): 555. CrossRef - Optimized transformation of Streptomyces sp. ATCC 39366 producing leptomycin by electroporation
Yong-Qiang Fan, Hong-Jian Liu, Li Yan, Yu-Shi Luan, Hai-Meng Zhou, Jun-Mo Yang, Shang-Jun Yin, Yu-Long Wang
Journal of Microbiology.2013; 51(3): 318. CrossRef - A Novel Alkaloid from Marine-Derived Actinomycete Streptomyces xinghaiensis with Broad-Spectrum Antibacterial and Cytotoxic Activities
Wence Jiao, Fenghua Zhang, Xinqing Zhao, Jiehan Hu, Joo-Won Suh, Marie-Joelle Virolle
PLoS ONE.2013; 8(10): e75994. CrossRef
- Identification and Characterization of an Autolysin Gene, atlA, from Streptococcus criceti
-
Haruki Tamura , Arisa Yamada , Hirohisa Kato
-
J. Microbiol. 2012;50(5):777-784. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2187-1
-
-
191
View
-
0
Download
-
1
Scopus
-
Abstract
-
AtlA of Streptococcus mutans is a major autolysin and belongs to glycoside hydrolase family 25 with cellosyl of Streptomyces coelicolor. The autolysin gene (atlA) encoding AtlA was identified from S. criceti. AtlA of S. criceti comprises the signal sequence in the N-terminus, the putative cell-wallbinding domain in the middle, and the catalytic domain in the C-terminus. Homology modeling analysis of the catalytic domain of AtlA showed the resemblance of the spatial arrangement of five amino acids around the predicted catalytic cavity to that of cellosyl. Recombinant AtlA and its four point mutants, D655A, D747A, W831A, and D849A, were evaluated on zymogram of S. criceti cells. Lytic activity was destroyed in the mutants D655A and D747A and diminished in the mutants W831A and D849A. These results suggest that Asp655 and Asp747 residues are critical for lytic activity and Trp831 and Asp849 residues are also associated with enzymatic activity.
- Genome-Wide Enrichment Screening Reveals Multiple Targets and Resistance Genes for Triclosan in Escherichia coli
-
Byung Jo Yu , Jung Ae Kim , Hyun Mok Ju , Soo-Kyung Choi , Seung Jin Hwang , Sungyoo Park , EuiJoong Kim , Jae-Gu Pan
-
J. Microbiol. 2012;50(5):785-791. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2439-0
-
-
186
View
-
0
Download
-
17
Crossref
-
Abstract
-
Triclosan is a widely used biocide effective against different microorganisms. At bactericidal concentrations, triclosan appears to affect multiple targets, while at bacteriostatic concentrations, triclosan targets FabI. The site-specific antibioticlike mode-of-action and a widespread use of triclosan in household products claimed to possibly induce cross-resistance to other antibiotics. Thus, we set out to define more systematically the genes conferring resistance to triclosan; A genomic library of Escherichia coli strain W3110 was constructed and enriched in a selective medium containing a lethal concentration of triclosan. The genes enabling growth in the presence of triclosan were identified by using a DNA microarray and confirmed consequently by ASKA clones overexpressing the selected 62 candidate genes. Among these, forty-seven genes were further confirmed to enhance the resistance to triclosan; these genes, including the FabI target, were involved in inner or outer membrane synthesis, cellsurface material synthesis, transcriptional activation, sugar phosphotransferase (PTS) systems, various transporter systems, cell division, and ATPase and reductase/dehydrogenase reactions. In particular, overexpression of pgsA, rcsA, or gapC conferred to E. coli cells a similar level of triclosan resistance induced by fabI overexpression. These results indicate that triclosan may have multiple targets other than well-known FabI and that there are several undefined novel mechanisms for the resistance development to triclosan, thus probably inducing cross antibiotic resistance.
-
Citations
Citations to this article as recorded by

- Environmental endocrine disruptors and pregnane X receptor action: A review
Yuan Liang, Yiyao Gong, Qiuyan Jiang, Yifan Yu, Jie Zhang
Food and Chemical Toxicology.2023; 179: 113976. CrossRef - Family Sphingomonadaceae as the key executor of triclosan degradation in both nitrification and denitrification systems
Huihui Dai, Jingfeng Gao, Dingchang Li, Zhiqi Wang, Yingchao Cui, Yifan Zhao
Chemical Engineering Journal.2022; 442: 136202. CrossRef - Metagenomics combined with DNA-based stable isotope probing provide comprehensive insights of active triclosan-degrading bacteria in wastewater treatment
Huihui Dai, Jingfeng Gao, Dingchang Li, Zhiqi Wang, Wanjun Duan
Journal of Hazardous Materials.2021; 404: 124192. CrossRef - The food-grade antimicrobial xanthorrhizol targets the enoyl-ACP reductase (FabI) in Escherichia coli
Yogiara, Elena A. Mordukhova, Dooil Kim, Won-Gon Kim, Jae-Kwan Hwang, Jae-Gu Pan
Bioorganic & Medicinal Chemistry Letters.2020; 30(24): 127651. CrossRef - The key active degrader, metabolic pathway and microbial ecology of triclosan biodegradation in an anoxic/oxic system
Huihui Dai, Jingfeng Gao, Shijie Wang, Dingchang Li, Zhiqi Wang
Bioresource Technology.2020; 317: 124014. CrossRef -
Biocide Exposure Induces Changes in Susceptibility, Pathogenicity, and Biofilm Formation in Uropathogenic
Escherichia coli
E. L. Henly, J. A. R. Dowling, J. B. Maingay, M. M. Lacey, T. J. Smith, S. Forbes
Antimicrobial Agents and Chemotherapy.2019;[Epub] CrossRef - Yeast: a microbe with macro-implications to antimicrobial drug discovery
Carl J. Balibar, Terry Roemer
Briefings in Functional Genomics.2016; 15(2): 147. CrossRef - Use of a predictive protocol to measure the antimicrobial resistance risks associated with biocidal product usage
Rebecca Wesgate, Pierre Grasha, Jean-Yves Maillard
American Journal of Infection Control.2016; 44(4): 458. CrossRef - Multiple adaptive routes of Salmonella enterica Typhimurium to biocide and antibiotic exposure
Tânia Curiao, Emmanuela Marchi, Denis Grandgirard, Ricardo León-Sampedro, Carlo Viti, Stephen L. Leib, Fernando Baquero, Marco R. Oggioni, José Luis Martinez, Teresa M. Coque
BMC Genomics.2016;[Epub] CrossRef - Bacterial genome engineering and synthetic biology: combating pathogens
Malathy Krishnamurthy, Richard T. Moore, Sathish Rajamani, Rekha G. Panchal
BMC Microbiology.2016;[Epub] CrossRef - Escherichia coli ASKA Clone Library Harboring tRNA-Specific Adenosine Deaminase (tadA) Reveals Resistance towards Xanthorrhizol
Yogiara, Dooil Kim, Jae-Kwan Hwang, Jae-Gu Pan
Molecules.2015; 20(9): 16290. CrossRef - Development of a Protocol for Predicting Bacterial Resistance to Microbicides
Laura Knapp, Alejandro Amézquita, Peter McClure, Sara Stewart, Jean-Yves Maillard, G. T. Macfarlane
Applied and Environmental Microbiology.2015; 81(8): 2652. CrossRef - Mutations upstream of fabI in triclosan resistant Staphylococcus aureus strains are associated with elevated fabI gene expression
Denis Grandgirard, Leonardo Furi, Maria Laura Ciusa, Lucilla Baldassarri, Daniel R Knight, Ian Morrissey, Carlo R Largiadèr, Stephen L Leib, Marco R Oggioni
BMC Genomics.2015;[Epub] CrossRef - Polymorphic Variation in Susceptibility and Metabolism of Triclosan-Resistant Mutants of Escherichia coli and Klebsiella pneumoniae Clinical Strains Obtained after Exposure to Biocides and Antibiotics
Tânia Curiao, Emmanuela Marchi, Carlo Viti, Marco R. Oggioni, Fernando Baquero, José Luis Martinez, Teresa M. Coque
Antimicrobial Agents and Chemotherapy.2015; 59(6): 3413. CrossRef - The impact of triclosan on the spread of antibiotic resistance in the environment
Daniel E. Carey, Patrick J. McNamara
Frontiers in Microbiology.2015;[Epub] CrossRef - Triclosan-Induced Aminoglycoside-Tolerant Listeria monocytogenes Isolates Can Appear as Small-Colony Variants
Vicky G. Kastbjerg, Line Hein-Kristensen, Lone Gram
Antimicrobial Agents and Chemotherapy.2014; 58(6): 3124. CrossRef - Recent advances in the potential interconnection between antimicrobial resistance to biocides and antibiotics
Marco R Oggioni, Leonardo Furi, Joana R Coelho, Jean-Yves Maillard, José L Martínez
Expert Review of Anti-infective Therapy.2013; 11(4): 363. CrossRef
- Characterization of Thermostable Deblocking Aminopeptidases of Archaeon Thermococcus onnurineus NA1 by Proteomic and Biochemical Approaches
-
Yeol Gyun Lee , Sun-Hee Leem , Young-Ho Chung , Seung Il Kim
-
J. Microbiol. 2012;50(5):792-797. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2461-2
-
-
262
View
-
0
Download
-
2
Crossref
-
Abstract
-
Thermococcus onnurineus NA1 is a hyperthermophilic archaeon that grows optimally at >80°C. The deblocking aminopeptidase (DAP) (TNA1-DAP1) encoded in Ton_1032 of T. onnurineus NA1 is considered a major DAP. However, four genes encoding putative DAP have been identified from a genomic analysis of T. onnurineus NA1. A proteomic analysis revealed that all four DAPs were differentially induced in YPS culture medium and, particularly, two DAPs (TNA1-DAP1 and TNA1-DAP2) were dominantly expressed in T. onnurineus NA1. The biochemical properties and enzyme activity of DAPs induced in an E. coli expression system suggested that the two major DAPs play complementary roles in T. onnurineus NA1.
-
Citations
Citations to this article as recorded by

- Proteomic Insights into Sulfur Metabolism in the Hydrogen-Producing Hyperthermophilic Archaeon Thermococcus onnurineus NA1
Yoon-Jung Moon, Joseph Kwon, Sung-Ho Yun, Hye Lim, Jonghyun Kim, Soo Kim, Sung Kang, Jung-Hyun Lee, Seung Kim, Young-Ho Chung
International Journal of Molecular Sciences.2015; 16(5): 9167. CrossRef - Characterization of Streptococcus pneumoniae N-acetylglucosamine-6-phosphate deacetylase as a novel diagnostic marker
Chi-Won Choi, Hee-Young An, Yong Ju Lee, Yeol Gyun Lee, Sung Ho Yun, Edmond Changkyun Park, Yeonhee Hong, Gun-Hwa Kim, Jae-Eun Park, Sun Jong Baek, Hyun Sik Kim, Seung Il Kim
Journal of Microbiology.2013; 51(5): 659. CrossRef
- Selection of a Streptomyces Strain Able to Produce Cell Wall Degrading Enzymes and Active against Sclerotinia sclerotiorum
-
Adriana Fróes , Andrew Macrae , Juliana Rosa , Marcella Franco , Rodrigo Souza , Rosângela Soares , Rosalie Coelho
-
J. Microbiol. 2012;50(5):798-806. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2060-2
-
-
221
View
-
0
Download
-
16
Crossref
-
Abstract
-
Control of plant pathogen Sclerotinia sclerotiorum is an ongoing challenge because of its wide host range and the persistence of its sclerotia in soil. Fungicides are the most commonly used method to control this fungus but these can have ecotoxicity impacts. Chitinolytic Streptomyces strains isolated from Brazilian tropical soils were capable of inhibiting S. sclerotiorum growth in vitro, offering new possibilities for integrated pest management and biocontrol, with a new approach to dealing with an old problem. Strain Streptomyces sp. 80 was capable of irreversibly inhibiting fungal growth. Compared to other strains, its crude enzymes had the highest chitinolytic levels when measured at 25°C and strongly inhibited sclerotia from S. sclerotiorum. It produced four hydrolytic enzymes involved in fungal cell wall degradation when cultured in presence of the fungal mycelium. The best production, obtained after three days, was 0.75 U/ml for exochitinase, 0.9 U/ml for endochitinase, 0.16 U/ml for glucanase, and 1.78 U/ml for peptidase. Zymogram analysis confirmed two hydrolytic bands of chitinolytic activity with apparent molecular masses of 45.8 and 206.8 kDa. One glucanase activity with an apparent molecular mass of 55 kDa was also recorded, as well as seven bands of peptidase activity with apparent molecular masses ranging from 15.5 to 108.4 kDa. Differential interference contrast microscopy also showed alterations of hyphal morphology after co-culture. Streptomyces sp. 80 seems to be promising as a biocontrol agent against S. sclerotiorum, contributing to the development of new methods for controlling plant diseases and reducing the negative impact of using fungicides.
-
Citations
Citations to this article as recorded by

- Biocontrol Potential of Streptomyces Strain FY4 Against Heterobasidion Root Rot Pathogen In Vitro
Yilin Li, Xuehai Li, Li Geng, Shijie Li, Ziwen Gao, Lin Huang, Lu-Min Vaario, Hui Sun
Forests.2024; 15(12): 2124. CrossRef - Streptomyces spp. as Biocontrol Agents of Fusarium Basal Rot on Shallots
Eka Wijayanti, Abdjad Asih Nawangsih, Efi Toding Tondok
Jurnal Fitopatologi Indonesia.2024; 20(2): 57. CrossRef - Effects of sulfamethoxazole and copper on the natural microbial community from a fertilized soil
Alessandra Narciso, Paola Grenni, Francesca Spataro, Chiara De Carolis, Jasmin Rauseo, Luisa Patrolecco, Gian Luigi Garbini, Ludovica Rolando, Maria Adelaide Iannelli, Maria Angeles Bustamante, Cristina Alvarez-Alonso, Anna Barra Caracciolo
Applied Microbiology and Biotechnology.2024;[Epub] CrossRef - A comprehensive review on soft rot disease management in ginger (Zingiber officinale) for enhancing its pharmaceutical and industrial values
Divyanshu Yadav, Harshita Gaurav, Ramanand Yadav, Raza Waris, Kareena Afzal, Amritesh Chandra Shukla
Heliyon.2023; 9(7): e18337. CrossRef - Mechanistic insights into the role of actinobacteria as potential biocontrol candidates against fungal phytopathogens
Talwinder Kaur, Kanika Khanna, Sonika Sharma, Rajesh K. Manhas
Journal of Basic Microbiology.2023; 63(11): 1196. CrossRef - Exploring the Potentiality of Native Actinobacteria to Combat the Chilli Fruit Rot Pathogens under Post-Harvest Pathosystem
Rajamuthu Renuka, Kupusamy Prabakar, Rangasamy Anandham, Lakshmanan Pugalendhi, Lingam Rajendran, Thiruvengadam Raguchander, Gandhi Karthikeyan
Life.2023; 13(2): 426. CrossRef - Plant Growth Promoting Actinobacteria, the Most Promising Candidates as Bioinoculants?
Zineb Faiza Boukhatem, Chahinez Merabet, Hassini Tsaki
Frontiers in Agronomy.2022;[Epub] CrossRef - The Significance of Mycoparasitism by Streptomyces sp. MBCN152-1 for Its Biocontrol Activity against Alternaria brassicicola
Masafumi Shimizu, Hushna Ara Naznin, Ayaka Hieno
Microbes and Environments.2022; 37(3): n/a. CrossRef - Sensitive immunochromatographic assay for the detection of the dimethachlone fungicide in tomatoes and lettuces
Jingjing Yao, Xinxin Xu, Haiying Liu, Liguang Xu, Liqiang Liu, Hua Kuang, Chuanlai Xu
New Journal of Chemistry.2022; 46(18): 8592. CrossRef - A Rhizobacterium, Streptomyces albulus Z1-04-02, Displays Antifungal Activity against Sclerotium Rot in Mungbean
On-Uma Ruangwong, Kaewalin Kunasakdakul, Sompong Chankaew, Kitsada Pitija, Anurag Sunpapao
Plants.2022; 11(19): 2607. CrossRef - Tackling Control of a Cosmopolitan Phytopathogen: Sclerotinia
Cathryn A. O’Sullivan, Katharina Belt, Louise F. Thatcher
Frontiers in Plant Science.2021;[Epub] CrossRef - Yeasts and Bacillus spp. as potential biocontrol agents of Sclerotinia sclerotiorum in garlic
Vytória Piscitelli Cavalcanti, Neilton Antonio Fiusa Araújo, Natália Bernardes Machado, Paulo Sérgio Pedroso Costa Júnior, Moacir Pasqual, Eduardo Alves, Kátia Regina Freitas Schwan-Estrada, Joyce Dória
Scientia Horticulturae.2020; 261: 108931. CrossRef - Overexpression of OsPGIP2 confers Sclerotinia sclerotiorum resistance in Brassica napus through increased activation of defense mechanisms
Zhuanrong Wang, Lili Wan, Qiang Xin, Ye Chen, Xiaohui Zhang, Faming Dong, Dengfeng Hong, Guangsheng Yang
Journal of Experimental Botany.2018; 69(12): 3141. CrossRef - Characterization of Trichoderma spp. antagonistic to Phytophthora colocasiae associated with leaf blight of taro
Vishnu Sukumari Nath, Neetha Soma John, Indira Parameswaran Anjanadevi, Vinayaka Mahabaleswar Hegde, Muthulekshmi Lajapathy Jeeva, Raj Shekhar Misra, Syamala Swayamvaran Veena
Annals of Microbiology.2014; 64(4): 1513. CrossRef - Effects of actinobacteria on plant disease suppression and growth promotion
Sasikumar Arunachalam Palaniyandi, Seung Hwan Yang, Lixin Zhang, Joo-Won Suh
Applied Microbiology and Biotechnology.2013; 97(22): 9621. CrossRef - Streptomyces lunalinharesiiStrain 235 Shows the Potential to Inhibit Bacteria Involved in Biocorrosion Processes
Juliana Pacheco da Rosa, Elisa Korenblum, Marcella Novaes Franco-Cirigliano, Fernanda Abreu, Ulysses Lins, Rosângela M. A. Soares, Andrew Macrae, Lucy Seldin, Rosalie R. R. Coelho
BioMed Research International.2013; 2013: 1. CrossRef
- In Vitro Development and Transfer of Resistance to Chlortetracycline in Bacillus subtilis
-
Menghong Dai , Junjie Lu , Yulian Wang , Zhenli Liu , Zonghui Yuan
-
J. Microbiol. 2012;50(5):807-812. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-1454-5
-
-
184
View
-
0
Download
-
12
Crossref
-
Abstract
-
The present criteria and rules controlling the approval of the use of probiotics are limited to antibiotic resistance patterns and the presence of antibiotic resistance genes in bacteria. There is little information available in the literature regarding the risk of the usage of probiotics in the presence of antibiotic pressure. In this study we investigated the development and transfer of antibiotic resistance in Bacillus subtilis selected in vitro by chlortetracycline in a stepwise manner. Bacillus subtilis was exposed to increasing concentrations of chlortetracyclineto induce in vitro resistance to chlortetracycline, and the minimal inhibitory concentrations were determinedfor the mutants. Resistant B. subtilis were conjugated with Escherichia coli NK5449 and Enterococcus faecalis JH2-2 using the filter mating. Three B. subtilis tetracycline resistant mutants (namely, BS-1, BS-2, and BS-3) were derived in vitro. A tetracycline resistant gene, tet (K), was found in the plasmids of BS-1 and BS-2. Three conjugates (BS-1N, BS-2N, and BS-3N) were obtained when the resistant B. subtilis was conjugated with E. coli NK5449. The conjugation frequencies for the BS-1N, BS-2N, and BS-3N conjugates were 4.57×10-7, 1.4×10-7, and 1.3×10-8, respectively. The tet(K) gene was found only in the plasmids of BS-1N. These results indicate that long-term use of probiotics under antibiotic selection pressure could cause antibiotic resistance, and the resistance gene could be transferred to other bacteria. The risk arising from the use of probiotics under antibiotic pressure should be considered in the criteria and rules for the safety assessment of probiotics.
-
Citations
Citations to this article as recorded by

- Searching, identifying and characterizing antagonistic isolates to control Neofabraea representatives causing bull’s-eye rot in apples
Klaudia Zawadzka, Karolina Oszust, Michał Pylak, Agata Gryta, Jacek Panek, Tomasz Lipa, Magdalena Frąc
International Agrophysics.2025; 39(2): 145. CrossRef - Antibiotic Resistance Gene Expression in Veterinary Probiotics: Two Sides of the Coin
Ádám Kerek, István Román, Ábel Szabó, Nikolett Palkovicsné Pézsa, Ákos Jerzsele
Veterinary Sciences.2025; 12(3): 217. CrossRef - Probiyotiklerin Genel Özellikleri ve Sağlık Üzerine Etkileri
Batuhan Horasan, Nevzat Atalay Çelikyürek
Sağlık Akademisi Kastamonu.2024; 9(2): 345. CrossRef - Tetracyclines resistance in Mycoplasma and Ureaplasma urogenital isolates derived from human: a systematic review and meta-analysis
Xiaoyan Wen, Mojgan Sarabi Nobakht, Yue Yang, Ebrahim Kouhsari, Sara Hajilari, Matin Zafar Shakourzadeh, Khalil Azizian
Annals of Clinical Microbiology and Antimicrobials.2023;[Epub] CrossRef - Bacillus Species as Direct-Fed Microbial Antibiotic Alternatives for Monogastric Production
Shifa A. Bahaddad, Meshal H. K. Almalki, Othman A. Alghamdi, Sayed S. Sohrab, Muhammad Yasir, Esam I. Azhar, Hichem Chouayekh
Probiotics and Antimicrobial Proteins.2023; 15(1): 1. CrossRef - Bacillusspore-forming probiotics: benefits with concerns?
Svetoslav Dimitrov Todorov, Iskra Vitanova Ivanova, Igor Popov, Richard Weeks, Michael Leonidas Chikindas
Critical Reviews in Microbiology.2022; 48(4): 513. CrossRef - Exploring the persistence and spreading of antibiotic resistance from manure to biocompost, soils and vegetables
Chengjun Pu, Yao Yu, Jianxiong Diao, Xiaoyan Gong, Ji Li, Ying Sun
Science of The Total Environment.2019; 688: 262. CrossRef - Bacillusprobiotics: an alternative to antibiotics for livestock production
S. Mingmongkolchai, W. Panbangred
Journal of Applied Microbiology.2018; 124(6): 1334. CrossRef - Distinguishing Effects of Ultraviolet Exposure and Chlorination on the Horizontal Transfer of Antibiotic Resistance Genes in Municipal Wastewater
Mei-Ting Guo, Qing-Bin Yuan, Jian Yang
Environmental Science & Technology.2015; 49(9): 5771. CrossRef - Probiotics: an update
Yvan Vandenplas, Geert Huys, Georges Daube
Jornal de Pediatria (Versão em Português).2015; 91(1): 6. CrossRef - Probiotics: an update
Yvan Vandenplas, Geert Huys, Georges Daube
Jornal de Pediatria.2015; 91(1): 6. CrossRef - Probiotics and Prebiotics in Infants and Children
Y. Vandenplas, E. De Greef, T. Devreker, G. Veereman-Wauters, B. Hauser
Current Infectious Disease Reports.2013; 15(3): 251. CrossRef
- The Production and Immunogenicity of Human Papillomavirus Type 58 Virus-like Particles Produced in Saccharomyces cerevisiae
-
Hye-Lim Kwag , Hyoung Jin Kim , Don Yong Chang , Hong-Jin Kim
-
J. Microbiol. 2012;50(5):813-820. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2292-1
-
-
279
View
-
0
Download
-
14
Crossref
-
Abstract
-
Human papillomavirus (HPV) is the cause of most cases of cervical cancer. HPV type 58 (HPV58) is the second most frequent cause of cervical cancer and high-grade squamous intraepithelial lesions (HSIL) in Asia and South / Central America, respectively. However, there is no vaccine against HPV58, although there are commercially available vaccines against HPV16 and 18. In this study, we produced HPV58 L1 protein from Saccharomyces cerevisiae, and investigated its immunogenicity. We first determined the optimum period of culture for obtaining HPV58 L1. We found that a considerable portion of the HPV58 L1 resulting from 48 h culture cannot be recovered by purification, while the HPV58 L1 resulting from 144 h culture is recovered efficiently: the yield of HPV58 L1 finally recovered from 144 h culture was 2.3 times higher than that from 48 h culture, although the production level of L1 protein from 144 h culture was lower than that from 48 h culture. These results indicate that the proportion of functional L1 protein from 144 h-cultured cells is significantly higher than that of 48 h-cultured cells. The HPV58 L1 purified from the 144 h culture was correctly assembled into structures similar to naturally occurring HPV virions. Immunization with the HPV58 L1 efficiently elicited anti-HPV58 neutralizing antibodies and antigen-specific CD4+ and CD8+ T cell proliferations, without the need for adjuvant. Our findings provide a convenient method for obtaining substantial amounts of highly immunogenic HPV58 L1 from S. cerevisiae.
-
Citations
Citations to this article as recorded by

- Expression, purification, and immunogenicity study of human papillomavirus type 52 virus-like particles produced in Hansenula polymorpha
Sheila Chairunnisa, Apon Zaenal Mustopa, Budiman Bela, Rosyida Khusniatul Arifah, Rifqiyah Nur Umami, Moh Egy Rahman Firdaus, Nurlaili Ekawati, Herman Irawan, Shasmita Irawan, Maritsa Nurfatwa, Ai Hertati, Sri Swasthikawati, Ela Novianti, Arizah Kusumawat
Biologicals.2025; 90: 101831. CrossRef - Yeast and Virus-like Particles: A Perfect or Imperfect Couple?
Sara Brachelente, Alvaro Galli, Tiziana Cervelli
Applied Microbiology.2023; 3(3): 805. CrossRef - Yeast-Based Virus-like Particles as an Emerging Platform for Vaccine Development and Delivery
Vartika Srivastava, Kripa N. Nand, Aijaz Ahmad, Ravinder Kumar
Vaccines.2023; 11(2): 479. CrossRef - How far have we explored fungi to fight cancer?
Chee Wun How, Yong Sze Ong, Sze Shin Low, Ashok Pandey, Pau Loke Show, Jhi Biau Foo
Seminars in Cancer Biology.2022; 86: 976. CrossRef - Yeast-based vaccines: New perspective in vaccine development and application
Ravinder Kumar, Piyush Kumar
FEMS Yeast Research.2019;[Epub] CrossRef - Advances in Designing and Developing Vaccines, Drugs and Therapeutic Approaches to Counter Human Papilloma Virus
Maryam Dadar, Sandip Chakraborty, Kuldeep Dhama, Minakshi Prasad, Rekha Khandia, Sameer Hassan, Ashok Munjal, Ruchi Tiwari, Kumaragurubaran Karthik, Deepak Kumar, Hafiz M. N. Iqbal, Wanpen Chaicumpa
Frontiers in Immunology.2018;[Epub] CrossRef - The codon-optimized capsid gene of duck circovirus can be highly expressed in yeast and self-assemble into virus-like particles
Cui YANG, Yu XU, Ren-yong JIA, Si-yang LIU, Ming-shu WANG, De-kang ZHU, Shun CHEN, Ma-feng LIU, Xin-xin ZHAO, Kun-feng SUN, Bo JING, Zhong-qiong YIN, An-chun CHENG
Journal of Integrative Agriculture.2017; 16(7): 1601. CrossRef - A novel trivalent HPV 16/18/58 vaccine with anti-HPV 16 and 18 neutralizing antibody responses comparable to those induced by the Gardasil quadrivalent vaccine in rhesus macaque model
Fei Yin, Yajun Wang, Na Chen, Dunquan Jiang, Yefeng Qiu, Yan Wang, Mei Yan, Jianping Chen, Haijiang Zhang, Yongjiang Liu
Papillomavirus Research.2017; 3: 85. CrossRef - EV71 virus-like particles produced by co-expression of capsid proteins in yeast cells elicit humoral protective response against EV71 lethal challenge
Xiaowen Wang, Xiangqian Xiao, Miao Zhao, Wei Liu, Lin Pang, Xin Sun, Shan Cen, Burton B. Yang, Yuming Huang, Wang Sheng, Yi Zeng
BMC Research Notes.2016;[Epub] CrossRef - Therapeutic potential of an AcHERV-HPV L1 DNA vaccine
Hee-Jung Lee, Jong Kwang Yoon, Yoonki Heo, Hansam Cho, Yeondong Cho, Yongdae Gwon, Kang Chang Kim, Jiwon Choi, Jae Sung Lee, Yu-Kyoung Oh, Young Bong Kim
Journal of Microbiology.2015; 53(6): 415. CrossRef - Immunogenicity of a Trivalent Human Papillomavirus L1 DNA-Encapsidated, Non-Replicable Baculovirus Nanovaccine
Hansam Cho, Hee-Jung Lee, Yoon-Ki Heo, Yeondong Cho, Yong-Dae Gwon, Mi-Gyeong Kim, Ki Hoon Park, Yu-Kyoung Oh, Young Bong Kim, Shibo Jiang
PLoS ONE.2014; 9(4): e95961. CrossRef - The Concentration of Carbon Source in the Medium Affects the Quality of Virus-Like Particles of Human Papillomavirus Type 16 Produced in Saccharomyces cerevisiae
Hyoung Jin Kim, Yingji Jin, Hong-Jin Kim, Paulo Lee Ho
PLoS ONE.2014; 9(4): e94467. CrossRef - Panorámica de los receptores celulares del virus del papiloma humano y su repercusión en la purificación de partículas semejantes a virus
J.F. Beltrán-Lissabet
Vacunas.2014; 15(1-2): 29. CrossRef - Virus-like particles for enterovirus 71 produced from Saccharomyces cerevisiae potently elicits protective immune responses in mice
Hao-Yang Li, Jian-Feng Han, Cheng-Feng Qin, Rong Chen
Vaccine.2013; 31(32): 3281. CrossRef
- Establishment and Characterization of the Epithelioma Papulosum Cyprini (EPC) Cell Line Persistently Infected with Infectious Pancreatic Necrosis Virus (IPNV), an Aquabirnavirus
-
Hyoung Jun Kim , Jae-Kwon Cho , Hyung-Kyu Hwang , Myung-Joo Oh , Toyohiko Nishizawa
-
J. Microbiol. 2012;50(5):821-826. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2364-2
-
-
282
View
-
0
Download
-
8
Crossref
-
Abstract
-
Infectious pancreatic necrosis virus (IPNV), a type species of aquabirnaviruses in the family Birnaviridae, is an etiological agent of infectious pancreatic necrosis and has been isolated from epizootics of cultured salmonids. In the present study, an epithelioma papulosum cyprini (EPC) cell line persistently infected with IPNV (PI-EPC) was experimentally established by subculturing EPC cells surviving IPNV infection, and was characterized. PI-EPC cells were morphologically indistinguishable from EPC, but continued to grow and yield IPNV. PI-EPC cells showed no cytopathic effect due to IPNV inoculation, and susceptibility of PI-EPC cells against heterologous viruses was not different from that of EPC cells. Only one cell of 103.5 PI-EPC cells produced IPNV at approximately 100.5 50% tissue culture infectious dose (TCID50)/cell/day, which was approximately 1,000 times lower than that of normal EPC cells. PI-EPC cells that did not yield IPNV (N-PI-EPC) were screened. The IPNV genome was detected from both PI-EPC and N-PI-EPC cells, and the IPNV VP2 structural protein was detected from both cell lines, but no other IPNV proteins were observed by Western blot analysis with anti-IPNV serum. Thus, multiplication of IPNV in PI-EPC cells was regulated by some host cell factors, except interferon.
-
Citations
Citations to this article as recorded by

- Fish cells persistently infected with nervous necrosis virus produce a small-molecule substance for reducing cellular metabolism and suppressing viral multiplication
Han Sol Lee, Toyohiko Nishizawa
Scientific Reports.2025;[Epub] CrossRef - RNA-seq analysis of a zebrafish caudal fin cell line in response to infection with spring viraemia of carp virus
Wenji Huang, Ning Ji, Xin Zhao, Jiahong Guo, Jianhua Feng, Kangyong Chen, Yaxin Wu, Junya Wang, Jun Zou
Aquaculture and Fisheries.2024; 9(2): 181. CrossRef - Development and characterization of megalocytivirus persistently-infected cell cultures for high yield of virus
Woo Ju Kwon, Min Ji Yoon, Ji Woong Jin, Kwang Il Kim, Young Chul Kim, Suhee Hong, Joon Bum Jeong, Hyun Do Jeong
Tissue and Cell.2020; 66: 101387. CrossRef - Characterization of Persistent Infection of Megalocytivirus in PMF Cell Line Derived from the Fin of Red Sea Bream Pagrus major
Min-Gyeong JEONG, Woo-Ju KWON, Joon-Gyu MIN, Hyun-Do JEONG
JOURNAL OF FISHRIES AND MARINE SCIENCES EDUCATION.2019; 31(6): 1639. CrossRef - INFECTIOUS PANCREATIC NECROSIS OF SALMONID FISH - DISTRIBUTION AND LABORATORY METHODS FOR DIAGNOSIS
E. Mileva
Trakia Journal of Sciences.2019; 17(4): 401. CrossRef - Infectious Hematopoietic Necrosis
Toyohiko Nishizawa, Mamoru Yoshimizu
Fish Pathology.2016; 52(1): 1. CrossRef - Multiple Passages of Grunt Fin Cells Persistently Infected with Red Seabream Iridovirus (RSIV) at 15ºC or 30ºC to Yield Uninfected Cells
So-Young Oh, Toyohiko Nishizawa
Journal of Aquatic Animal Health.2016; 28(4): 214. CrossRef - A Novel Disorder of Cultured Juvenile Greater Amberjack Seriola dumerili Characterized by Renomegaly and Splenomegaly
Shinpei Wada, Osamu Kurata, Hitoshi Hatakeyama, Azumi Yamashita, Shusaku Takagi, Toyohiko Nishizawa, Hiroshi Yokoyama
Fish Pathology.2014; 49(1): 7. CrossRef
Journal Article
- Possible Translocation of Periodontal Pathogens into the Lymph Nodes Draining the Oral Cavity
-
G. Amodini Rajakaruna , Makoto Umeda , Keisuke Uchida , Asuka Furukawa , Bae Yuan , Yoshimi Suzuki , Ebe Noriko , Yuichi Izumi , Yoshinobu Eishi
-
J. Microbiol. 2012;50(5):827-836. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2030-8
-
-
215
View
-
0
Download
-
20
Crossref
-
Abstract
-
Numerous publications have reported the presence of periodontopathogenic bacteria in peripheral and central vascular lesions. However, it is unclear how this bacterial translocation occurs. The objective of this study was to investigate whether periodontopathic bacteria are translocated to lymph nodes proximal to the oral cavity. Obtaining lymph node samples is not ethically feasible unless they are excised as part of the surgical management of patients with cancer. This study analyzed formalin-fixed and paraffin-embedded lymph nodes, histologically negative for cancer cell invasion, that were excised from 66 patients with histories of head and neck cancer. Real-time PCR was performed to amplify the 16S ribosomal DNA fragments from Porphyromonas gingivalis, Treponema denticola, Aggregatibacter actinomycetemcomitans, Tannerella forsythia, and Prevotella intermedia. The relationship between bacterial detection and cancer severity, gender, and the use of anti-cancer therapy was examined by Fisher’s exact test. P. gingivalis, T. forsythia, and P. intermedia were present in 17%, 8%, and 8% of the samples of submandibular and submental lymph nodes, respectively. There were no significant relationships between bacterial detection and the cancer disease status, patient gender or use of anticancer therapy. According to these data, it appears that the translocation of periodontopathic bacteria may occur via lymphatic drainage, irrespective of the cancer disease status, gender or anticancer therapy.
-
Citations
Citations to this article as recorded by

- Upper gastrointestinal tract microbiota with oral origin in relation to oesophageal squamous cell carcinoma
Shegan Gao, Zichao Zhang, Kui Sun, Meng-Xiang Li, Yi-Jun Qi
Annals of Medicine.2023;[Epub] CrossRef - Porphyromonas gingivalis regulates atherosclerosis through an immune pathway
Qijun Ruan, Peng Guan, Weijuan Qi, Jiatong Li, Mengying Xi, Limin Xiao, Sulan Zhong, Dandan Ma, Jia Ni
Frontiers in Immunology.2023;[Epub] CrossRef - The preventive effects of perioperative oral care on surgical site infections after pancreatic cancer surgery: a retrospective study
Hiroshi Nobuhara, Yasuhiro Matsugu, Junko Tanaka, Tomoyuki Akita, Keiko Ito
Supportive Care in Cancer.2022; 30(4): 3337. CrossRef - 術前口腔環境の適正化
浩 延原, 康弘 眞次, 圭子 伊藤
The Japanese Journal of SURGICAL METABOLISM and NUTRITION.2021; 55(5): 166. CrossRef - Periodontal disease and cancer: Epidemiologic studies and possible mechanisms
Ngozi Nwizu, Jean Wactawski‐Wende, Robert J. Genco
Periodontology 2000.2020; 83(1): 213. CrossRef - Unculturable and culturable periodontal-related bacteria are associated with periodontal inflammation during pregnancy and with preterm low birth weight delivery
Changchang Ye, Zhongyi Xia, Jing Tang, Thatawee Khemwong, Yvonne Kapila, Ryutaro Kuraji, Ping Huang, Yafei Wu, Hiroaki Kobayashi
Scientific Reports.2020;[Epub] CrossRef - How the evolving epidemics of opioid misuse and HIV infection may be changing the risk of oral sexually transmitted infection risk through microbiome modulation
Wiley D. Jenkins, Lauren B. Beach, Christofer Rodriguez, Lesli Choat
Critical Reviews in Microbiology.2020; 46(1): 49. CrossRef - The periodontopathic bacteria in placenta, saliva and subgingival plaque of threatened preterm labor and preterm low birth weight cases: a longitudinal study in Japanese pregnant women
Changchang Ye, Sayaka Katagiri, Naoyuki Miyasaka, Hiroaki Kobayashi, Thatawee Khemwong, Toshiyuki Nagasawa, Yuichi Izumi
Clinical Oral Investigations.2020; 24(12): 4261. CrossRef - Fretibacterium sp. human oral taxon 360 is a novel biomarker for periodontitis screening in the Japanese population
Thatawee Khemwong, Hiroaki Kobayashi, Yuichi Ikeda, Takanori Matsuura, Takeaki Sudo, Chihiro Kano, Ryo Mikami, Yuichi Izumi, David M. Ojcius
PLOS ONE.2019; 14(6): e0218266. CrossRef - Eubacterium saphenum as a Novel Bacterial Biomarker for Periodontitis Screening
Thatawee KHEMWONG, Hiroaki KOBAYASHI, Yuichi IKEDA, Takeaki SUDO, Chihiro KANO, Takanori MATSUURA, Yuichi IZUMI
THE JOURNAL OF THE STOMATOLOGICAL SOCIETY,JAPAN.2018; 85(2): 62. CrossRef - Oral hygiene might prevent cancer
Oscar J. Cordero, Rubén Varela-Calviño
Heliyon.2018; 4(10): e00879. CrossRef - Localization and density of Porphyromonas gingivalis and Tannerella forsythia in gingival and subgingival granulation tissues affected by chronic or aggressive periodontitis
G. Amodini Rajakaruna, Mariko Negi, Keisuke Uchida, Masaki Sekine, Asuka Furukawa, Takashi Ito, Daisuke Kobayashi, Yoshimi Suzuki, Takumi Akashi, Makoto Umeda, Walter Meinzer, Yuichi Izumi, Yoshinobu Eishi
Scientific Reports.2018;[Epub] CrossRef - Periodontal Disease and Incident Cancer Risk among Postmenopausal Women: Results from the Women's Health Initiative Observational Cohort
Ngozi N. Nwizu, James R. Marshall, Kirsten Moysich, Robert J. Genco, Kathleen M. Hovey, Xiaodan Mai, Michael J. LaMonte, Jo L. Freudenheim, Jean Wactawski-Wende
Cancer Epidemiology, Biomarkers & Prevention.2017; 26(8): 1255. CrossRef - 周術期口腔ケアによる消化器外科術後の感染性合併症に対する予防効果
The Japanese Journal of SURGICAL METABOLISM and NUTRITION.2017; 51(4): 165. CrossRef - The oral cavity microbiota: between health, oral disease, and cancers of the aerodigestive tract
Pierre Le Bars, Sébastien Matamoros, Emmanuel Montassier, Françoise Le Vacon, Gilles Potel, Assem Soueidan, Fabienne Jordana, Marie-France de La Cochetière
Canadian Journal of Microbiology.2017; 63(6): 475. CrossRef - Gingipain‐dependent augmentation by Porphyromonas gingivalis of phagocytosis of Tannerella forsythia
Y.‐J. Jung, H.‐K. Jun, B.‐K. Choi
Molecular Oral Microbiology.2016; 31(6): 457. CrossRef - Inverse Association of Plasma IgG Antibody to Aggregatibacter actinomycetemcomitans and High C-Reactive Protein Levels in Patients with Metabolic Syndrome and Periodontitis
Supanee Thanakun, Suchaya Pornprasertsuk-Damrongsri, Misa Gokyu, Hiroaki Kobayashi, Yuichi Izumi, Özlem Yilmaz
PLOS ONE.2016; 11(2): e0148638. CrossRef - The inflammasome and danger molecule signaling: at the crossroads of inflammation and pathogen persistence in the oral cavity
Özlem Yilmaz, Kyu Lim Lee
Periodontology 2000.2015; 69(1): 83. CrossRef - Neck Masses in Children
Amy Eapen, Deepak Kamat
Clinical Pediatrics.2014; 53(11): 1027. CrossRef - Looking in the Porphyromonas gingivalis cabinet of curiosities: the microbium, the host and cancer association
K.R. Atanasova, Ö. Yilmaz
Molecular Oral Microbiology.2014; 29(2): 55. CrossRef
Research Support, Non-U.S. Gov'ts
- Intestinal Intraepithelial TCRγδ+ T Cells are Activated by Normal Commensal Bacteria
-
Sang Phil Jeong , Jung-Ah Kang , Sung-Gyoo Park
-
J. Microbiol. 2012;50(5):837-841. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2468-8
-
-
229
View
-
0
Download
-
9
Crossref
-
Abstract
-
TCRγδ+ T cells play a critical role in protecting the intestinal mucosa against pathogenic infection. In the absence of infection, TCRγδ+ T cell activation must be continuously regulated by T regulatory cells (Treg) to prevent the development of colitis. However, the activation of intestinal TCRγδ+ T cells under normal conditions has not been clearly resolved. In order to determine TCRγδ+ T cell activation in vivo, we designed an NF-κB based reporter system. Using the recombinant lentiviral method, we delivered the NF-κB reporter to isolated TCRγδ+ T cells, which were then adoptively transferred into normal mice. Our data indicate that the NF-κB activation level in TCRγδ+ T cells is higher in the intestinal intraepithelial layer than in the lamina propria region. In addition, the surface expression level of lymphocyte activation marker CD69 in TCRγδ+ T cells is also higher in the intestinal intraepithelial layer and this activation was reduced by Sulfatrim treatment which removes of commensal bacteria. Collectively, our data indicate that the TCRγδ+ T cell population attached to the intestinal lumen is constitutively activated even by normal commensal bacteria.
-
Citations
Citations to this article as recorded by

- Gamma-delta T cells suppress microbial metabolites that activate striatal neurons and induce repetitive/compulsive behavior in mice
Laura M. Cox, Bruna K. Tatematsu, Lydia Guo, Danielle S. LeServe, Julia Mayrink, Marilia G. Oliveira, Dustin Donnelly, Roberta C. Fonseca, Luisa Lemos, Toby B. Lanser, Ana C. Rosa, Juliana R. Lopes, Luke A. Schwerdtfeger, Gabriela F.C. Ribeiro, Eduardo L.
Brain, Behavior, and Immunity.2024; 117: 242. CrossRef - Gamma-delta T cells modulate the microbiota and fecal micro-RNAs to maintain mucosal tolerance
Rafael M. Rezende, Laura M. Cox, Thais G. Moreira, Shirong Liu, Selma Boulenouar, Fyonn Dhang, Danielle S. LeServe, Brenda N. Nakagaki, Juliana R. Lopes, Bruna K. Tatematsu, Luisa Lemos, Julia Mayrink, Eduardo L. C. Lobo, Lydia Guo, Marilia G. Oliveira, C
Microbiome.2023;[Epub] CrossRef - Oral tolerance: an updated review
Rafael M. Rezende, Howard L. Weiner
Immunology Letters.2022; 245: 29. CrossRef - Role of orally induced regulatory T cells in immunotherapy and tolerance
Thais B. Bertolini, Moanaro Biswas, Cox Terhorst, Henry Daniell, Roland W. Herzog, Annie R. Piñeros
Cellular Immunology.2021; 359: 104251. CrossRef - Mechanisms of Maintenance of Foot-and-Mouth Disease Virus Persistence Inferred From Genes Differentially Expressed in Nasopharyngeal Epithelia of Virus Carriers and Non-carriers
James J. Zhu, Carolina Stenfeldt, Elizabeth A. Bishop, Jessica A. Canter, Michael Eschbaumer, Luis L. Rodriguez, Jonathan Arzt
Frontiers in Veterinary Science.2020;[Epub] CrossRef - History and mechanisms of oral tolerance
Rafael M. Rezende, Howard L. Weiner
Seminars in Immunology.2017; 30: 3. CrossRef - γδ T Cells Coexpressing Gut Homing α4β7 and αE Integrins Define a Novel Subset Promoting Intestinal Inflammation
Jeong-su Do, Sohee Kim, Karen Keslar, Eunjung Jang, Emina Huang, Robert L Fairchild, Theresa T Pizarro, Booki Min
The Journal of Immunology.2017; 198(2): 908. CrossRef - CD69 Is the Crucial Regulator of Intestinal Inflammation: A New Target Molecule for IBD Treatment?
Katarina Radulovic, Jan Hendrik Niess
Journal of Immunology Research.2015; 2015: 1. CrossRef - Peroxisome-localized hepatitis Bx protein increases the invasion property of hepatocellular carcinoma cells
Jae-Min Han, Jung-Ah Kang, Min-Hee Han, Kyung-Hun Chung, Cho-Rong Lee, Woo-Keun Song, Youngsoo Jun, Sung-Gyoo Park
Archives of Virology.2014; 159(10): 2549. CrossRef
- Antifungal Activity of Leuconostoc citreum and Weissella confusa in Rice Cakes
-
Eunjong Baek , Hyojin Kim , Hyejung Choi , Sun Yoon , Jeongho Kim
-
J. Microbiol. 2012;50(5):842-848. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2153-y
-
-
235
View
-
0
Download
-
39
Crossref
-
Abstract
-
The antifungal activity of organic acids greatly improves the shelf life of bread and bakery products. However, little is known about the effect of lactic acid fermentation on fungal contamination in rice cakes. Here, we show that lactic acid fermentation in rice dough can greatly retard the growth of three fungal species when present in rice cakes, namely Cladosporium sp. YS1, Neurospora sp. YS3, and Penicillium crustosum YS2. The antifungal activity of the lactic acid bacteria against these fungi was much better than that of 0.3% calcium propionate. We found that organic acids including lactic and acetic acid, which are byproducts of lactic fermentation or can be artificially added, were the main antifungal substances. We also found that some Leuconostoc citreum and Weissella confusa strains could be good starter species for rice dough fermentation. These results imply that these lactic acid bacteria can be applicable to improve the preservation of rice cakes.
-
Citations
Citations to this article as recorded by

- Antifungal potential of Lactobacillus bioactive metabolites: synergistic interactions with food preservatives and molecular docking insights
Ahmed M. Emara, Diaa A. Marrez, Asmaa S. Ramadan, Ahmed A. El-Rashedy, Ahmed Noah Badr, Karolina Hoppe, Hongjun Li, Zhifei He
European Food Research and Technology.2025; 251(9): 2761. CrossRef - Lactic Acid Bacteria–Derived Secondary Metabolites: Emerging Natural Alternatives for Food Preservation
Riza Jane S. Banicod, Nazia Tabassum, Aqib Javaid, Young-Mog Kim, Fazlurrahman Khan
Probiotics and Antimicrobial Proteins.2025;[Epub] CrossRef - Antimicrobial Properties of Thermally Processed Oyster Shell Powder for Use as Calcium Supplement
Sungmo Ahn, Soohwan Lee, Seokwon Lim
Foods.2025; 14(15): 2579. CrossRef - Purification and structural characterization of APTs, a novel antifungal peptide produced by Lactobacillus paracasei ALAC-4, and its inhibitory effect on Candida albicans
Jing Dong, Lin Zhu, Ziyu Sun, Mandlaa, Zhongjun Chen
LWT.2024; 199: 116077. CrossRef - Optimization of pile-fermentation process, quality and microbial diversity analysis of dark hawk tea (Machilus rehderi)
Yongyi Yang, Juan Peng, Qingqing Li, Qinfei Song, Quentin Cronk, Biao Xiong
LWT.2024; 192: 115707. CrossRef - Potential of Lactic Acid Bacteria and Bacillus spp. in a Bio-Detoxification Strategy for Mycotoxin Contaminated Wheat Grains
Sandra Mischler, Amandine André, Susette Freimüller Leischtfeld, Nadina Müller, Irene Chetschik, Susanne Miescher Schwenninger
Applied Microbiology.2024; 4(1): 96. CrossRef - Changes in microbial community during the factory production of sweet dumplings from glutinous rice determined by high-throughput sequencing analysis
Biao Suo, Zijie Dong, Yangyang Huang, Peng Guan, Xiaojie Wang, Huiping Fan, Zhongmin Huang, Zhilu Ai
LWT.2023; 180: 114689. CrossRef - Evaluation of Antifungal Metabolites Produced by Lactic Acid Bacteria
Joanna Ivy Irorita Fugaban, Eun Sung Jung, Svetoslav Dimitrov Todorov, Wilhelm Heinrich Holzapfel
Probiotics and Antimicrobial Proteins.2023; 15(5): 1447. CrossRef - Evaluation of antifungal activity of lactic acid bacteria against fungi in simulated cheese matrix
Luana Virgínia Souza, Raiane Rodrigues da Silva, Andressa Falqueto, Andressa Fusieger, Evandro Martins, Cinzia Caggia, Cinzia Lucia Randazzo, Antonio Fernandes de Carvalho
LWT.2023; 182: 114773. CrossRef - Biocontrol of Rhizoctonia solani in basmati rice by the application of Lactobacillus and Weissella spp.
Maira Akhtar, Asia Nosheen, Rumana Keyani, Humaira Yasmin, Rabia Naz, Saqib Mumtaz, Muhammad Nadeem Hassan
Scientific Reports.2023;[Epub] CrossRef - Recent developments in antifungal lactic acid bacteria: Application, screening methods, separation, purification of antifungal compounds and antifungal mechanisms
Hong Chen, Xiaohai Yan, Gengan Du, Qi Guo, Yiheng Shi, Jiale Chang, Xiaoyu Wang, Yahong Yuan, Tianli Yue
Critical Reviews in Food Science and Nutrition.2023; 63(15): 2544. CrossRef - Removal of aflatoxin M1 from milk and aqueous medium by indigenously isolated strains of W. confusa H1 and L. plantarum S2
Himani J. Chaudhary, Ami R. Patel
Food Bioscience.2022; 45: 101468. CrossRef - Antifungal Preservation of Food by Lactic Acid Bacteria
Ahmad Nasrollahzadeh, Samira Mokhtari, Morteza Khomeiri, Per E. J. Saris
Foods.2022; 11(3): 395. CrossRef - Biological control for basal rot in yellow pitahaya fruits (Selenicereus megalanthus): Ex vivo trials
Luisa F. Lozada, Cristobal N. Aguilar, Claudia L. Vargas, Carolina M. Bedoya, Liliana Serna-Cock
Journal of King Saud University - Science.2022; 34(5): 102042. CrossRef - Microbial enrichment evaluation during the fermentation of ensiling pruned branches from tea plants
Shiqi Lin, Huihui Huang, Jinglei Zheng, Haiyu Lin, Yuefei Wang, Ping Xu
International Journal of Food Microbiology.2022; 374: 109742. CrossRef - Effects of hexanoic acid on microbial communities, fermentation, and hygienic quality of corn silages infested with toxigenic fungi
Wenbo Wang, Xin Yang, Junfeng Li, Zhihao Dong, Jie Zhao, Tao Shao, Xianjun Yuan
Journal of the Science of Food and Agriculture.2022; 102(9): 3522. CrossRef - Antipathogenic Action and Antibiotic Sensitivity Pattern of the Borhani-Associated Lactic Acid Bacterium Weissella confusa LAB-11
Tanim Jabid Hossain, Iqbal Hossain Nafiz, Halima Akter Mozumder, Ferdausi Ali, Nabila Rahman, Md. Sajib Khan
SSRN Electronic Journal .2022;[Epub] CrossRef - Biotechnological and Medical Aspects of Lactic Acid Bacteria Used for Plant Protection: A Comprehensive Review
Simon Bergsma, Gerrit Jan Willem Euverink, Nikolaos Charalampogiannis, Efthymios Poulios, Thierry K. S. Janssens, Spyridon Achinas
BioTech.2022; 11(3): 40. CrossRef - Antifungal activity of lactic acid bacteria isolated from kunu-zaki, a cereal-based Nigerian fermented beverage
Omotade Richard Ogunremi, Susette Freimüller Leischtfeld, Sandra Mischler, Susanne Miescher Schwenninger
Food Bioscience.2022; 49: 101648. CrossRef - Effect of Lactic Acid Bacteria on the Fermentation Quality and Mycotoxins Concentrations of Corn Silage Infested with Mycotoxigenic Fungi
Jinyang Li, Wenbo Wang, Sifan Chen, Tao Shao, Xuxiong Tao, Xianjun Yuan
Toxins.2021; 13(10): 699. CrossRef -
Broad‐spectrum antimicrobial efficacy of
Pediococcus acidilactici
LAB001 against food spoilage and toxigenic bacteria and fungi
Sucheta Das, Vivekananda Mandal, Narayan Chandra Mandal
Journal of Food Processing and Preservation.2021;[Epub] CrossRef - Multifunctional properties and safety evaluation of lactic acid bacteria and yeasts associated with fermented cereal doughs
Marcel Houngbédji, S. Wilfrid Padonou, Charles Parkouda, Pernille Greve Johansen, Mathias Hounsou, B. Pélagie Agbobatinkpo, Hagretou Sawadogo-Lingani, Lene Jespersen, D. Joseph Hounhouigan
World Journal of Microbiology and Biotechnology.2021;[Epub] CrossRef - Comparison of the antifungal effect of undissociated lactic and acetic acid in sourdough bread and in chemically acidified wheat bread
Els Debonne, Fien Van Schoors, Peter Maene, Filip Van Bockstaele, Pieter Vermeir, Jan Verwaeren, Mia Eeckhout, Frank Devlieghere
International Journal of Food Microbiology.2020; 321: 108551. CrossRef - Organic acids and 2,4-Di-tert-butylphenol: major compounds of Weissella confusa WM36 cell-free supernatant against growth, survival and virulence of Salmonella Typhi
Wattana Pelyuntha, Chaiyavat Chaiyasut, Duangporn Kantachote, Sasithorn Sirilun
PeerJ.2020; 8: e8410. CrossRef - All‐around management of a fungal isolate obtained from cheese spoilage as an environmental source: Direct approach from an undergrad student to a biotechnological characterization
Eugenia Guadalupe Ortiz Lechuga, Omar Eduardo Tovar Herrera, Katiushka Arévalo Niño
Biochemistry and Molecular Biology Education.2019; 47(6): 681. CrossRef - Novel approaches for chemical and microbiological shelf life extension of cereal crops
Marcus Schmidt, Emanuele Zannini, Kieran M. Lynch, Elke K. Arendt
Critical Reviews in Food Science and Nutrition.2019; 59(21): 3395. CrossRef - Antifungal Activity of Lactic Acid Bacteria Combinations in Dairy Mimicking Models and Their Potential as Bioprotective Cultures in Pilot Scale Applications
Marcia Leyva Salas, Anne Thierry, Mathilde Lemaître, Gilles Garric, Marielle Harel-Oger, Manon Chatel, Sébastien Lê, Jérôme Mounier, Florence Valence, Emmanuel Coton
Frontiers in Microbiology.2018;[Epub] CrossRef - Mold spoilage of bread and its biopreservation: A review of current strategies for bread shelf life extension
Claudia Axel, Emanuele Zannini, Elke K. Arendt
Critical Reviews in Food Science and Nutrition.2017; 57(16): 3528. CrossRef - Fate of Escherichia coli O157:H7 and bacterial diversity in corn silage contaminated with the pathogen and treated with chemical or microbial additives
I.M. Ogunade, Y. Jiang, D.H. Kim, A.A. Pech Cervantes, K.G. Arriola, D. Vyas, Z.G. Weinberg, K.C. Jeong, A.T. Adesogan
Journal of Dairy Science.2017; 100(3): 1780. CrossRef - Biocontrol potential of Lactobacillus strains isolated from corn silages against some plant pathogenic fungi
Zohreh Akhavan Kharazian, Gholamreza Salehi Jouzani, Mahnaz Aghdasi, Mohammad Khorvash, Majid Zamani, Hamid Mohammadzadeh
Biological Control.2017; 110: 33. CrossRef - Identification of antifungal peptides produced by Lactobacillus plantarum IS10 grown in the MRS broth
Belal J. Muhialdin, Zaiton Hassan, Fatimah Abu Bakar, Nazamid Saari
Food Control.2016; 59: 27. CrossRef - Antifungal-activity-producing lactic acid bacteria as biocontrol agents in plants
Milind H. Gajbhiye, Balu P. Kapadnis
Biocontrol Science and Technology.2016; 26(11): 1451. CrossRef - Appraisal of lactic acid bacteria as protective cultures
Kontham Kulangara Varsha, Kesavan Madhavan Nampoothiri
Food Control.2016; 69: 61. CrossRef - Screening for antimicrobial and proteolytic activities of lactic acid bacteria isolated from cow, buffalo and goat milk and cheeses marketed in the southeast region of Brazil
Fabricio L Tulini, Nolwenn Hymery, Thomas Haertlé, Gwenaelle Le Blay, Elaine C P De Martinis
Journal of Dairy Research.2016; 83(1): 115. CrossRef - Anoxia and anaerobic respiration are involved in “spawn-burning” syndrome for edible mushroom Pleurotus eryngii grown at high temperatures
Rui Ying Zhang, Dan Dan Hu, Yong Yue Zhang, Paul H. Goodwin, Chen Yang Huang, Qiang Chen, Wei Gao, Xiang Li Wu, Ya Jie Zou, Ji Bin Qu, Jin Xia Zhang
Scientia Horticulturae.2016; 199: 75. CrossRef - Isolation of antifungal activity of Leuconostoc mesenteroides TA from kimchi and characterization of its antifungal compounds
Seol Hwa Lee, Hae Choon Chang
Food Science and Biotechnology.2016; 25(1): 213. CrossRef - Current perspectives on antifungal lactic acid bacteria as natural bio-preservatives
Sarah Crowley, Jennifer Mahony, Douwe van Sinderen
Trends in Food Science & Technology.2013; 33(2): 93. CrossRef - Transcriptomic and morphological profiling of Aspergillus fumigatus Af293 in response to antifungal activity produced by Lactobacillus plantarum 16
Sarah Crowley, Jennifer Mahony, John P. Morrissey, Douwe van Sinderen
Microbiology
.2013; 159(Pt_10): 2014. CrossRef - Fermentation of rice flour with Weissella koreensis HO20 and Weissella kimchii HO22 isolated from kimchi and its use in the making of jeolpyeon
Hyejung Choi, Hwawon Lee, Sun Yoon
Korean journal of food and cookery science.2013; 29(3): 267. CrossRef
- NOTE] Antifungal Activity of Extracellular Hydrolases Produced by Autolysing Aspergillus nidulans Cultures
-
Melinda Szilágyi , Fruzsina Anton , Katalin Forgács , Jae-Hyuk Yu , István Pócsi , Tamás Emri
-
J. Microbiol. 2012;50(5):849-854. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2001-0
-
-
235
View
-
0
Download
-
8
Crossref
-
Abstract
-
Carbon-starving Aspergillus nidulans cultures produce high activities of versatile hydrolytic enzymes and, among these, ChiB endochitinase and EngA β-1,3-endoglucanase showed significant antifungal activity against various fungal species. Double deletion of engA and chiB diminished the antifungal activity of the fermentation broths and increased conidiogenesis and long-term viability of A. nidulans, but decreased the growth rate on culture media containing weak carbon sources. Production of ChiB and EngA can influence fungal communities either directly due to their antifungal properties or indirectly through their effects on vegetative growth. Our data suggest saprophytic fungi as promising future candidates to develop novel biocontrol technologies.
-
Citations
Citations to this article as recorded by

-
Application and antagonistic mechanisms of atoxigenic
Aspergillus
strains for the management of fungal plant diseases
Suyan Wang, Yanxia Wang, Xinchi Shi, Daniela D. Herrera-Balandrano, Xin Chen, Fengquan Liu, Pedro Laborda, Irina S. Druzhinina
Applied and Environmental Microbiology.2024;[Epub] CrossRef - Identification and evaluation of Aspergillus tubingensis as a potential biocontrol agent against grey mould on tomato
Juan Zhao, Weicheng Liu, Dewen Liu, Caige Lu, Dianpeng Zhang, Huiling Wu, Dan Dong, Lingling Meng
Journal of General Plant Pathology.2018; 84(2): 148. CrossRef - Autolytic enzymes are responsible for increased melanization of carbon stressed Aspergillus nidulans cultures
Melinda Szilágyi, Fruzsina Anton, István Pócsi, Tamás Emri
Journal of Basic Microbiology.2018; 58(5): 440. CrossRef - Tricking Arthrinium malaysianum into Producing Industrially Important Enzymes Under 2-Deoxy D-Glucose Treatment
Soumya Mukherjee, Mathu Malar Chandrababunaidu, Arijit Panda, Suman Khowala, Sucheta Tripathy
Frontiers in Microbiology.2016;[Epub] CrossRef - γ-Glutamyl transpeptidase (GgtA) of Aspergillus nidulans is not necessary for bulk degradation of glutathione
Zsolt Spitzmüller, Nak-Jung Kwon, Melinda Szilágyi, Judit Keserű, Viktória Tóth, Jae-Hyuk Yu, István Pócsi, Tamás Emri
Archives of Microbiology.2015; 197(2): 285. CrossRef - Investigating Aspergillus nidulans secretome during colonisation of cork cell walls
Isabel Martins, Helga Garcia, Adélia Varela, Oscar Núñez, Sébastien Planchon, Maria Teresa Galceran, Jenny Renaut, Luís P.N. Rebelo, Cristina Silva Pereira
Journal of Proteomics.2014; 98: 175. CrossRef - Transcriptome changes initiated by carbon starvation in Aspergillus nidulans
Melinda Szilágyi, Márton Miskei, Zsolt Karányi, Béla Lenkey, István Pócsi, Tamás Emri
Microbiology.2013; 159(Pt_1): 176. CrossRef - Interactions between naturally occurring antifungal agents
Viktória Tóth, Melinda Szilágyi, Fruzsina Anton, Éva Leiter, I. Pócsi, T. Emri
Acta Biologica Hungarica.2013; 64(4): 510. CrossRef
- NOTE] Burkholderia denitrificans sp. nov., Isolated from the Soil of Dokdo Island, Korea
-
Chang-Muk Lee Lee , Hang-Yeon Weon , Sang-Hong Yoon , Soo-Jin Kim , Bon-Sung Koo , Soon-Wo Kwon
-
J. Microbiol. 2012;50(5):855-859. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-1554-2
-
-
191
View
-
0
Download
-
9
Crossref
-
Abstract
-
A novel, Gram-negative, bacterial strain KIS30-44T was identified from wet forest soil collected on the Korean island of Dokdo. Growth of the strain was observed at 15–30°C, pH 5−9, 0–3% NaCl, and 950 mM KNO3. KIS30-44T reduced nitrate to nitrogen gas. Analysis of the 16S rRNA gene sequence showed that KIS30-44T was phylogenetically related to Burkholderia sacchari, Burkholderia mimosarum, and Burkholderia oxyphila (98.1%, 98.0%, and 98.0% sequence similarity, respectively). The genomic G+C content was 63.5 mol%. KIS30-44T exhibited less than 52% DNA-DNA relatedness with the type strains of 9 closely related Burkholderia species. The major isoprenoid quinone was Q-8. The polar lipid profile consisted of diphosphatidylglycerol, phosphatidylethanolamine, phosphatidylglycerol and two unknown aminolipids. The major fatty acids in KIS30-44T were C16:0, C18:1 ω7c and summed feature 3 (iso-C15:0 2-OH and C16:1 ω7c), and the strain contained half the amount of C17:0 cyclo found in the 9 closely related Burkholderia species. The results of these phenotypic, 16S rRNA gene sequence, DNA-DNA hybridization, and chemotaxonomic data indicate that KIS30-44T represents a novel species within the genus Burkholderia, for which the name Burkholderia denitrificans (Type strain KIS30-44T =KACC 12733T =DSM 24336T) is proposed.
-
Citations
Citations to this article as recorded by

- The history and distribution of nodulating Paraburkholderia, a potential inoculum for Fynbos forage species
Chrizelle W. Beukes, Stephanus N. Venter, Emma T. Steenkamp
Grass and Forage Science.2021; 76(1): 10. CrossRef -
Paraburkholderia madseniana sp. nov., a phenolic acid-degrading bacterium isolated from acidic forest soil
Roland C. Wilhelm, Sean J. L. Murphy, Nicole M. Feriancek, David C. Karasz, Christopher M. DeRito, Jeffrey D. Newman, Daniel H. Buckley
International Journal of Systematic and Evolutionary Microbiology
.2020; 70(3): 2137. CrossRef - Paraburkholderia lycopersici sp. nov., a nitrogen-fixing species isolated from rhizoplane of Lycopersicon esculentum Mill. var. Saladette in Mexico
Erika Yanet Tapia-García, Ivan Arroyo-Herrera, Fernando Uriel Rojas-Rojas, J. Antonio Ibarra, María Soledad Vásquez-Murrieta, Lourdes Martínez-Aguilar, Isabel M. López-Lara, William B. Whitman, Paulina Estrada de los Santos
Systematic and Applied Microbiology.2020; 43(6): 126133. CrossRef - Insights into the methanogenic degradation of N, N-dimethylformamide: The functional microorganisms and their ecological relationships
Zhe Kong, Lu Li, Jiang Wu, Tao Zhang, Yu-You Li
Bioresource Technology.2019; 271: 37. CrossRef - Paraburkholderia dokdonella sp. nov., isolated from a plant from the genus Campanula
Man-Young Jung, Myung-Suk Kang, Ki-Eun Lee, Eun-Young Lee, Soo-Je Park
Journal of Microbiology.2019; 57(2): 107. CrossRef - Burkholderia jirisanensis sp. nov., isolated from forest soil
Seil Kim, Gyeongtaek Gong, Han Min Woo, Yunje Kim, Youngsoon Um
International Journal of Systematic and Evolutionary Microbiology.2016; 66(3): 1260. CrossRef -
Burkholderia humisilvae sp. nov., Burkholderia solisilvae sp. nov. and Burkholderia rhizosphaerae sp. nov., isolated from forest soil and rhizosphere soil
Jae-Chan Lee, Kyung-Sook Whang
International Journal of Systematic and Evolutionary Microbiology
.2015; 65(Pt_9): 2986. CrossRef - Molecular signatures and phylogenomic analysis of the genus Burkholderia: proposal for division of this genus into the emended genus Burkholderia containing pathogenic organisms and a new genus Paraburkholderia gen. nov. harboring environmental species
Amandeep Sawana, Mobolaji Adeolu, Radhey S. Gupta
Frontiers in Genetics.2014;[Epub] CrossRef - List of new names and new combinations previously effectively, but not validly, published
International Journal of Systematic and Evolutionary Microbiology
.2013; 63(Pt_1): 1. CrossRef
- NOTE] Next-Generation Sequencing-Based Genome-Wide Mutation Analysis of L-Lysine-Producing Corynebacterium glutamicum ATCC 21300 Strain
-
Chang-Soo Lee , Jae-Young Nam , Eun-Suk Son , O-chul Kwon , Woorijarang Han , Jae-Yong Cho , Young-Jin Park
-
J. Microbiol. 2012;50(5):860-863. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2109-2
-
-
235
View
-
0
Download
-
9
Crossref
-
Abstract
-
In order to identify single nucleotide polymorphism and insertion/deletion mutations, we performed whole-genome re-sequencing of the enhanced L-lysine-producing Corynebacterium glutamicum ATCC 21300 strain. In total, 142 single nucleotide polymorphisms and 477 insertion/deletion mutations were identified in the ATCC 21300 strain when compared to 3,434 predicted genes of the wild-type C. glutamicum ATCC 13032 strain. Among them, 110 transitions and 29 transversions of single nucleotide polymorphisms were found from genes of the ATCC 21300 strain. In addition, 11 genes, involved in the L-lysine biosynthetic pathway and central carbohydrate metabolism, contained mutations including single nucleotide polymorphisms and insertions/deletions. Interestingly, RT-PCR analysis of these 11 genes indicated that they were normally expressed in the ATCC 21300 strain. This information of genome-wide gene-associated variations will be useful for genome breeding of C. glutamicum in order to develop an industrial amino acidproducing strain with minimal mutation.
-
Citations
Citations to this article as recorded by

- Review of the Proteomics and Metabolic Properties of Corynebacterium glutamicum
Juhwan Park, Sooa Lim
Microorganisms.2024; 12(8): 1681. CrossRef - Recent advances in the metabolic engineering and physiological opportunities for microbial synthesis of L-aspartic acid family amino acids: A review
Yusheng Wang, Yunlong Bai, Qi Zeng, Zeyuan Jiang, Yuzhe Liu, Xiyan Wang, Xiaoting Liu, Chunlei Liu, Weihong Min
International Journal of Biological Macromolecules.2023; 253: 126916. CrossRef - Obtaining a series of native gradient promoter-5′-UTR sequences in Corynebacterium glutamicum ATCC 13032
Ning Li, Weizhu Zeng, Sha Xu, Jingwen Zhou
Microbial Cell Factories.2020;[Epub] CrossRef - The BFK20 phage replication origin confers a phage-encoded resistance phenotype to the industrial strain Brevibacterium flavum
Gabriela Bukovska, Jana Ugorcakova, Nora Halgasova, Lucia Bocanova, Adela Tkacova
FEMS Microbiology Letters.2019;[Epub] CrossRef - L-lysine production improvement: a review of the state of the art and patent landscape focusing on strain development and fermentation technologies
Fernanda Karine do Carmo Félix, Luiz Alberto Junior Letti, Gilberto Vinícius de Melo Pereira, Pedro Gabriel Borges Bonfim, Vanete Thomaz Soccol, Carlos Ricardo Soccol
Critical Reviews in Biotechnology.2019; 39(8): 1031. CrossRef - Comparative analysis of Corynebacterium glutamicum genomes: a new perspective for the industrial production of amino acids
Junjie Yang, Sheng Yang
BMC Genomics.2017;[Epub] CrossRef - White biotechnology: State of the art strategies for the development of biocatalysts for biorefining
S. Heux, I. Meynial-Salles, M.J. O'Donohue, C. Dumon
Biotechnology Advances.2015; 33(8): 1653. CrossRef - Characterization of a Corynebacterium glutamicum dnaB mutant that shows temperature-sensitive growth and mini-cell formation
Makoto Uchida, Takashi Hirasawa, Masaaki Wachi
Archives of Microbiology.2014; 196(12): 871. CrossRef - Next-generation sequencing-based transcriptome analysis of l-lysine-producing Corynebacterium glutamicum ATCC 21300 strain
Hong-Il Kim, Jae-Young Nam, Jae-Yong Cho, Chang-Soo Lee, Young-Jin Park
Journal of Microbiology.2013; 51(6): 877. CrossRef
- NOTE] Caenimonas terrae sp. nov., Isolated from a Soil Sample in Korea, and Emended Description of the Genus Caenimonas Ryu et al. 2008
-
Soo-Jin Kim , Hang-Yeon Weon , Yi-Seul Kim , Ji Young Moon , Soon Ja Seok , Seung-Beom Hong , Soon-Wo Kwon
-
J. Microbiol. 2012;50(5):864-868. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-1587-6
-
-
184
View
-
0
Download
-
14
Scopus
-
Abstract
-
A white-coloured bacterium, SGM1-15T, was isolated from a paddy soil sample from Suwon, Republic of Korea. The cells were strictly aerobic, Gram-negative and curved rodshaped. A phylogenetic analysis based on 16S rRNA gene sequences revealed that strain SGM1-15T was closely related to Curvibacter delicatus LMG 4328T (97.6% similarity) and Caenimonas koreensis EMB320T (97.5% similarity). The major respiratory quinone system was Q-8 and the predominant cellular fatty acids were C16:0 (39.9%), summed feature 3 (C16:1 ω7c and/or iso-C15:0 2-OH; 24.3%) and C17:0 cyclo (22.7%). The major polar lipids were diphosphatidylglycerol, phosphatidylglycerol and phosphatidylethanolamine. The major polyamines were 2-hydroxypurescine, purescine and spermidine. The DNA G+C content was 68.7 mol%. On the basis of the phylogenetic, physiologicl and chemotaxonomic data, stain SGM1-15T represents a novel species of the genus Caenimonas, for which the name Caenimonas terrae sp. nov. is proposed. The type strain of Caenimonas terrae is SGM1-15T (=KACC 13365T =NBRC 106341T).
- NOTE] Envelope Diversity, Characteristics of V3 Region and Predicted Co-Receptor Usage of Human Immunodeficiency Viruses Infecting North Indians
-
Raiees Andrabi , Rajesh Kumar , Manju Bala , Ambili Nair , Prakash SS , Vandana Kushwaha , Kalpana Luthra
-
J. Microbiol. 2012;50(5):869-873. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2136-z
-
-
162
View
-
0
Download
-
9
Scopus
-
Abstract
-
Subtypes of human immunodeficiency virus type 1 circulating in 21 north Indian patients were characterized based on the partial sequence of the gp120 envelope protein. A majority of viruses (85.7%, 18/21) were subtype C, while 14.3% (3/21) were subtype A. Sequence analysis revealed that the V3 region was highly conserved compared with V4 and V5. The predicted use of co-receptors indicated exclusive usage of R5, except for two subtype A viruses (AIIMS279 and AIIMS281). Our results demonstrate conservation within the V3 loop of subtype C viruses, and suggest the emergence of non-clade C viruses in the north Indian population.
- NOTE] Construction and Characterisation of an Antifungal Recombinant Bacillus thuringiensis with an Expanded Host Spectrum
-
Qin Liu , Jong Yul Roh , Yong Wang , Jae Young Choi , Xue Ying Tao , Jae Su Kim , Yeon Ho Je
-
J. Microbiol. 2012;50(5):874-877. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2201-7
-
-
171
View
-
0
Download
-
6
Scopus
-
Abstract
-
A novel antifungal Bacillus thuringiensis strain 19–22, ssp. kurstaki (H3a3b3c), was characterised. This strain included cry1Aa, cry1Ab, cry1Ac, and cry1D, which have high insecticidal activities against lepidopteran larvae other than Spodoptera exigua. To expand the host spectrum, a cry1E gene whose product is active against S. exigua was introduced into the isolate. The transformant successfully expressed the Cry1E protein without any loss of its original antifungal activities. These results indicate that this recombinant strain exhibits dual activities and may be used as an integrated control agent to control plant diseases and insect pests.
- NOTE] Regulatory Characteristics of the Vibrio vulnificus rtxHCA Operon Encoding a MARTX Toxin
-
Jinseo Park , Seung Min Kim , Hee Gon Jeong , Sang Ho Choi
-
J. Microbiol. 2012;50(5):878-881. Published online September 21, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2479-5
-
-
193
View
-
0
Download
-
6
Crossref
-
Abstract
-
Vibrio vulnificus MARTX encoded by rtxA, an open reading frame of the rtxHCA operon, is essential for virulence in vitro and in mice. In this study, a primer extension analysis revealed that transcription of the rtxHCA operon begins at a single site, and is under the direction of a single promoter, PrtxHCA. PrtxHCA activity appeared at the beginning of growth and reached a maximum in mid-exponential phase. PrtxHCA activity was induced by exposure to INT-407 cells, and the membrane fraction of INT-407 cells was the most effective for the induction.
-
Citations
Citations to this article as recorded by

- Rifampicin‐resistant RpoB S522L Vibrio vulnificus exhibits disturbed stress response and hypervirulence traits
Laura Cutugno, Conor O'Byrne, Jan Pané‐Farré, Aoife Boyd
MicrobiologyOpen.2023;[Epub] CrossRef - Vibrio vulnificus PlpA facilitates necrotic host cell death induced by the pore forming MARTX toxin
Changyi Cho, Sanghyeon Choi, Myung Hee Kim, Byoung Sik Kim
Journal of Microbiology.2022; 60(2): 224. CrossRef -
A MARTX Toxin
rtxA
Gene Is Controlled by Host Environmental Signals through a CRP-Coordinated Regulatory Network in Vibrio vulnificus
Zee-Won Lee, Seung-Ho Hwang, Garam Choi, Kyung Ku Jang, Tae Hee Lee, Kyung Min Chung, Byoung Sik Kim, Sang Ho Choi, Caroline S. Harwood
mBio.2020;[Epub] CrossRef - Spatiotemporal Regulation of Vibrio Exotoxins by HlyU and Other Transcriptional Regulators
Byoung Sik Kim
Toxins.2020; 12(9): 544. CrossRef - Low cell density regulator AphA upregulates the expression of Vibrio vulnificus iscR gene encoding the Fe-S cluster regulator IscR
Jong Gyu Lim, Jin Hwan Park, Sang Ho Choi
Journal of Microbiology.2014; 52(5): 413. CrossRef - VvpM, an extracellular metalloprotease of Vibrio vulnificus, induces apoptotic death of human cells
Mi-Ae Lee, Jeong-A Kim, Yu Jin Yang, Mee-Young Shin, Soon-Jung Park, Kyu-Ho Lee
Journal of Microbiology.2014; 52(12): 1036. CrossRef
- NOTE] Identification of Chaperones in Freeze Tolerance in Saccharomyces cerevisiae
-
Mahendran Chinnamara Naicker , I Seul Jo , Hana Im
-
J. Microbiol. 2012;50(5):882-887. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2411-z
-
-
179
View
-
0
Download
-
10
Scopus
-
Abstract
-
Exposure to low temperatures reduces protein folding rates and induces the cold denaturation of proteins. Considering the roles played by chaperones in facilitating protein folding and preventing protein aggregation, chaperones must exist that confer tolerance to cold stress. Here, yeast strains lacking individual chaperones were screened for reduced freezing tolerance. In total, 19 of 82 chaperone-deleted strains tested were more sensitive to freeze-thaw treatment than wild-type cells. The reintroduction of the respective chaperone genes into the deletion mutants recovered the freeze tolerance. The freeze sensitivity of the chaperone-knockout strains was also retained in the presence of 20% glycerol.
Journal Article
- NOTE] Winogradskyella jejuensis sp. nov., a Marine Bacterium Isolated from a Brown Alga Carpopeltis affinis
-
Ji-Young Kim , Duck-Chul Oh
-
J. Microbiol. 2012;50(5):888-892. Published online November 4, 2012
-
DOI: https://doi.org/10.1007/s12275-012-2447-0
-
-
156
View
-
0
Download
-
13
Scopus
-
Abstract
-
A Gram-negative, orange-pigmented, rod-shaped bacterium, designated strain CP32T was isolated from a brown alga Carpopeltis affinis collected on the coast of Jeju Island, Republic of Korea. The isolate grew at 10–37°C (optimum 25°C) and at pH 6.5–9.5 (optimum pH 7.0). The 16S rRNA gene sequence of the isolate showed much similarity with the type strains of recognized species of the genus Winogradskyella (94.0–96.6%). The most closely related species were Winogradskyella echinorum KMM 6211T, Winogradskyella ulvae KMM 6390T, Winogradskyella thalassocola KMM 3907T, Winogradskyella poriferorum UST030701-295T, and Winogradskyella eximia KMM 3944T. The major respiratory quinone was menaquinone-6 (MK-6) and the predominant cellular fatty acids were iso-C15:1 G (24.8%), iso-C15:0 (23.4%), and iso-C17:0 3-OH (11.6 %). The DNA G+C content was 33.3 mol%. The polar lipid profile was composed of phosphatidylethanolamine, two aminolipids, and five unknown lipids. On the basis of phenotypic features, and the result of 16S rRNA gene sequence analysis, strain CP32T (=KCTC 23835T =JCM 18454T) represents a novel species of the genus Winogradskyella, for which the name Winogradskyella jejuensis sp. nov. is proposed.
- Erratum] Phycicoccus ochangensis sp. nov., Isolated from Soil of a Potato Cultivation Field
-
Hyangmi Kim , Hyun-Woo Oh , Doo-Sang Park , Kang Hyun Lee , Sung Uk Kim , Hee-Moon Park , Kyung Sook Bae Bae
-
J. Microbiol. 2012;50(5):893-893.
-
-
-
Abstract
-
In the article by Kim et al. that appears in the Journal of Microbiology 2012; 50, 349-353. KCTC number on page 349 (abstract line 19) and page 353 (left paragraph line 32) should read as KCTC 19695 not KCTC 19694, and on page 353 (left paragraph
line 33) should read as KCTC 19694 not KCTC 19695.