Journal of Microbiology

Production of a monoclonal antibody and ultrastructure of the sporozoite of cryptosporidium parvum: Choi, Young Sook , Lee, Sung Tae , Cho, Myung Hwan; J. Microbiol. 1996;34(4):379-383.

Abstract: Cryptosporidium Parvum causes a life-threatening diarrhea in acquired immunodeficiency syndrome (AIDS) patients. The sporozoite stage of C. parvum has been known to be a target in treating cryptosporidiosis in AIDS patients as it is an extracellular stage. A sporozoite was ultrastructurally observed. It has a crescent shape with a rounded posterior end and a tapering body. The compact nucleus was located at the posterior end. A monoclonal antibody was produced, which recognized a 43 kDa of sporozoite antigens in a western blot analysis and showed the surface labeling in immunofluorescence.

Search