- The comparison of microbial communities in thyroid tissues from thyroid carcinoma patients
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Chen-Jian Liu , Si-Qian Chen , Si-Yao Zhang , Jia-Lun Wang , Xiao-Dan Tang , Kun-Xian Yang , Xiao-Ran Li
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J. Microbiol. 2021;59(11):988-1001. Published online October 6, 2021
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DOI: https://doi.org/10.1007/s12275-021-1271-9
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Thyroid carcinoma is a common endocrine organ cancer associated
with abnormal hormone secretion, leading to the
disorder of metabolism. The intestinal microbiota is vital to
maintain digestive and immunologic homeostasis. The relevant
information of the microbial community in the gut and
thyroid, including composition, structure, and relationship,
is unclear in thyroid carcinoma patients. A total of 93 samples
from 25 patients were included in this study. The results
showed that microbial communities existed in thyroid tissue;
gut and thyroid had high abundance of facultative anaerobes
from the Proteobacteria phyla. The microbial metabolism from
the thyroid and gut may be affected by the thyroid carcinoma
cells. The cooccurrence network showed that the margins of
different thyroid tissues were unique areas with more competition;
the stabilization of microcommunities from tissue
and stool may be maintained by several clusters of species
that may execute different vital metabolism processes dominantly
that are attributed to the microenvironment of cancer.
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Citations
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- Endophytic Fungi Diversity of Aquatic/Riparian Plants and Their Antifungal Activity In Vitro
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Hai-Yan Li , Chun-An Zhao , Chen-Jian Liu , Xiao-Fei Xu
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J. Microbiol. 2010;48(1):1-6. Published online March 11, 2010
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DOI: https://doi.org/10.1007/s12275-009-0163-1
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Two hundred and fourteen endophytic fungi were isolated from 500 segments of aquatic/riparian plants Ottelia acuminata, Myriophyllum verticillatum, Equisetum arvense, Cardamine multijuga, and Impatiens chinensis. They were identified to 31 taxa in which Cladosporium, Fusarium, and Geotrichum were the dominant genera.
Among all isolates, 169 (79%) were anamorphic fungi, 1 (0.5%) was an teleomorphic ascomycete and 44 (21%) were sterile mycelia. There were significant differences in the colonization frequency of endophytes between the five plant species (X~2=51.128, P<0.001, Chi-square test). The riparian plants harboured more
endophytes than the submerged plants. The antifungal activity of these isolates against Fusarium solani and Phytophthora nicotianae in vitro were tested and 28 (13.1%) isolates showed antifungal activities with more than 30% growth inhibition rate against the two pathogens.
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